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58 Cards in this Set

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  • Back
What are the signs of an atropine overdose?
-Atropine is and anticholinergic, antispasmodic, antidysrhythmic
<>Signs of overdose are:
Hot as a Hare (Increased temp)
Mad as a Hatter (confusion, delirium)
Red as a Beet (Flushed face)
Dry as a bone (Decrased secretions, thirsty)
What is the mechanism of action of Atropine?
<>It is an anticholinergic, antispasmodic and antidysrhythmic which works by:
-Inhibiting the action of acetylchline. Primary effects are on the heart, exocrine glands, smooth muscles, and eye.
What are the uses for Atropine?
-Anitdysrhythmic--increases heart rate
-Preoperative--decreases secretions, prevents bradycardia
-Relaxes smooth muscles--bronchi, bladder, GI tract
What are the side effects of atropine?
Dry mouth, tachycardia, blurred vision, urinary hesitancy.
What are the important nursing implications to know when giving atropine?
-Evaluate frequently for urinary retention, especially in elderly men with prostate problems
-Do not administer if client has tachycardia.
What type of drug is Phenazopyridine (Pyridium)?
Urinary Tract analgesic. It works by exerting topical analgesic effect on the urinary tract mucosa.
When is Phenazopyridine (Pyridium) used?
-Relief of pain, burning, urgency, frequency resulting from lower urinary tract mucosa irritation.
What are the side effect of Phenazopyridine (Pyridium)?
Bright orange colored urine.
What is important teaching instructions for a patient on Phenazopyridine (Pyridium)?
-Teach client how to avoid upper urinary tract infections.
-Take with meals
-Explain discoloration of urine (reddish orange).
-The drug may discolor contact lenses and stain underwear.
What is important nursing implications for Phenazopyridine (Pyridium)?
Do not crush, break, or chew tablet.
What is the use for Potassium Chloride?
Potassium deficiency. (Potassium deficiency or excess can cause deadly heart problems)
What is the mechanism of action of Potassium Chloride?
It is necessary for nerve impulse conduction; maintains electrical excitability of the heart and assists to regulate acid base balance.
What are the side effects of Potassium Chloride?
-Gastrointestinal discomfort--n/v
-Diarrhea and abdominal discomfort
-Hypoerkalemia--can lead to ventricular tachycardia.
What are important nursing implications for administering Potassium Chloride?
-Monitor serum potassium (3.5-5.5 mEq/L normal value)
-Watch for signs of renal insufficiency (increased creatinine, increased blood urea nitrogen)
-IV potassium must ALWAYS be diluted before administering. NEVER ADMINISTER POTASSIUM IV PUSH!!!
What are the signs of salicylate poisoning?
Initial symptoms: Tinnitus, sweating, headache and dizziness
Toxicity: Hyperthermia, sweating, and dehydration; respiratory depression, resulting in respiratory acidosis, stupor and coma
Severe toxicity: Metabolic acidosis, seizures
What is the treatment of salicylate poisoning?
-Gastric lavage with activated charcoal
-Oxygen or ventilation assistance as necessary
-Treat for hyperthermia (external cool down, tepid water sponge bath), dehydration (intravenous hydration, balance pH and electrolytes), and reverse acidosis (slow infusion of bicarbonate)
-Dialysis if necessary
What are the important teaching points for patients taking salicylate (aspirin) to avoid poisoning?
-Teach parents safe medication storage
-Teach parents not to administer aspirin to children who are suspected of having a viral infection, especially chicken pox or influenza
-If child complains of any tinnitus, aspirin should be discontinued; parents should have child evaluation
--Pretty sure children should not take aspirin at all??
What should a nurse do when evaluating a patient with salicylate toxicity?
Monitor respiratory status, blood gases and for progression of symptoms.
What is the toxic level of Salicylate for a 30lb child?
12 adult aspirin (325 mg) or 48 baby aspirin (81 mg)
What is the therapeutic and toxic level of Lithium?
Therapeutic: 0.8 to 1.4 mEq/L
Toxic: 2.0 mEq/L
What is the toxic level of Digoxin?
2.0 ng/ml
What is the toxic level of Theophylline?
20 mcg/ml
When should Lithium levels be drawn?
Drawn in the morning, 12 hours after the evening dose.
What is the most common cause of Lithium toxicity?
Sodium depletion causes lithium retention.
What are the side effects of lithium at therapeutic levels?
fine hand tremors, nausea, diarrhea, anorexia, fatigue, weakness, headache, polyuria, and thirst
What are the effects of lithium toxicity?
1.5-2.0: persistent GI problems (vomiting, diarrhea), course remors, hyperirritability, poor coordination
Above 2.0 mEq/L: ataxia, high output of dilute urine, ECG changes, tinnitus, blurred vision, severe hypotension, symptoms may progress to coma and death.
What is the optimal level of Digoxin? And what is the most common predisposing factor to toxicity?
0.5 to 0.8 ng/ml

Hypokalemia is the most common predisposing factor causing toxicity.
What are the S/S of digoxin toxicity
Anorexia, N/V, fatigue, DYSRHYTHMIAS.
What is the optimal level of Theophylline?
5 to 15 mcg/ml
What are the S?S of theophylline toxicity?
Too rapid intravenous infusion may cause hypotension, tachycardia, hyperventilation
-Severe dysrhythmias and seizures.
Why does Grapefruit juice effect the potency of many medications?
The juice inhibits intestinal enzymes and decreases drug metabolism.
When a patient is on what medications should they avoid drinking grapefruit juice?
-Calcium Channel Blockers (Felopdipine [Plendil], Nifedipine [Procardia], Amolodipine [Norvasc], Verapamil [Calan])
-Other drugs:
>Carbamazepine (Tegratol)
>Buspirone (Buspar)
>Lovastatin (Mevacor)
>Cyclosporine (Sandimmune)
>Saquinavir (Invirase)
-Benzodiazepines (Halcion, Valium)
What is the action of Lidocaine when being used as an emergency drug?
Slows conduction, reduces automaticity and increases repolarization of cardiac cycle.
What is the use of Lidocaine as an emergency drug?
IV preparation only for ventricular dysrhythmias (frequent premature ventricular beats, ventricular tachycardia)
What is the use of Epinephrine (Adrenalin) as an emergency drug?
Bronchodilation in clients with acute asthma; treatment of hypersensitivity, anaphylactic reactions, cardiac arrests, produces mydriasis for opthalmologic procedures.
What is the mechanism of action of epinephrine as an emergency medication?
Vasoconstirction, increases heart rate and blood pressure, bronchodilator. Treatment of choice for anaphylacitic reactions.
What is the action of Atropine as an emergency drug?
Selectively blocks cholinergic receptors; increases heart rate in bradycardia; decreases secretions.
What is the uses of atropine as an emergency drug?
Symptomatic bradycardia, decreases respiratory secretions, reverses effects of anticholinesterase medications.
What is the use of Naloxone (Narcan) as an emergency drug?
+Narcotic (opioid) antagonist
-Reversal of overdose by opioid analgesics (morphine, demerol, oxytocin); opioid-induced respiratory depression; may be used in neonates to counteract or treat effects from narcotics given to mother during labor.
What is the mechanism of action of Naloxone (Narcon) as an emergency drug?
Blocks narcotic effects; reverses opiate-induced sleep or dedication; increases respiratory rate and blood pressure.
What are the adverse reactions of cytotoxic anticancer drugs?
Bone marrow suppression, N/V, Anorexia, GI disturbances, Alopecia,
-It is important Avoid pregnancy
What is important about handing and administration of cytotoxic anticancer drugs?
Avoid direct contact with skin, eyes and mucous membranes when involved in the administration of the medication.
What are the various types of Cytotoxic anticancer drugs?
Alkylating agents, antimetabolites, antitumor antibiotics, mitotic inhibitors, platinum compounds, topoisomerase inhibitors.
What are common side effects for oral calcium supplements?
GI disturbances (N/V, constipation)
-Renal dysfunction (polyuria, stonres)
-CNS effects (lethargy, depression)
What are important nursing implications when administering calcium supplements?
-Encourage fluids with medications
-Increase fiber-containing foods to decrease constipation.
-Encourage client to check with health care provider regarding calcium and cardiac medications.
What type of medication is Timolol (Timoptic)?
Beta-adrenergic blocker used for open-angle and aphakic glaucoma. (usually in a gel or drops form)
What is the mechanism of action of Timolol (Timoptic)?
Most commonly used as ophthamlmic gel or drops to reduce production of aqueous humor to promote a decrease in intraocular pressure. When systemically absorbed, also causes blockade of beta-receptors producing effects on the heart and lungs.
What are important patient teaching points for a client taking Timolol (Timoptic)?
-Teach how to correctly administer eye drops
-Teach client to apply slight pressure at the inner canthus for one minute after instillation. This will help decrease the systemic absorption of the medicaiton.
-Client taking Timolol should not administer any OTC nasal decongestants or cold preparations.
What are important nursing implications when caring for a client taking Timolol (Timoptic)?
Assess client for systemic absorption of medication (bradycardia, hypotension)
What side effects should be watched for in a patient taking TImolol (Timoptic)?
Watch for: rash, dizziness, headache, ocular irritation
What type of medication is Naphazoline hydrochloride?
They are Topical vasoconstrictors, sympathomimetic (decongestant).
What are the uses of Naphazoline hydrochloride?
Topical Vasoconstrictor.
Used For:
Ophthalmic: relief of itching, congestion and minor irritations.
Intranasal: relief of nasal congestion as a result of common cold, acute or chronic rhinitis, hay fever, or allergies
What are the common side effects of Naphazoline?
Burning, stinging, and dry nasal passages.
What are the important nursing implications for a patient taking Naphazoline Hydrochloride?
-Too frequent use of topical agents may result in the rebound effect.
-Watch for pupil dilation, intraocular pressure, and rebound redness of the eyes.
What are important patient teaching points for a patient taking Naphazoline Hydrochloride?
-Instruct the client to use caution with activities that require visual acuity.
-Do not use formore than 3 days without a health care provider's direction.
-Caustion clients with hypertension to avoid use of OTC decongestants.
What are the two types of medications that effect the amount Pyridoxine (B6) vitamins and what are the used for?
-Isoniazid (INH)--increases the B6. Antituberculin Agent
-Levodopa: Lowers the B6. Antiparkinsonism.
What are the important patient teaching points for a client taking medications that affect the amount of Pyridoxine (Vitamin B6).
-Clients taking Isoniazid (INH) need an increased intake of Vitamin B6 to prevent deficiency.
-Clients taking levodopa need a decreased intake of vitamin B6 which reverses the effects of the levodopa.
=Teach client about dietary sources: meats and fish, especially organ meats; heavily fortified cereals and soy-based products.
What are important nursing implications for a client taking medications that affect the amount of pyridoxine (Vitamin B6)?
-Perform neurologic checks in the client with vitamin B6 issues.
-Deficiency most often occurs in combinations with deficiency of other B vitamins in alcoholic clients.