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11 Cards in this Set

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  • Back
For GLAUCOMA. Acts on ciliary muscle which secondarily pulls on slceral spur and opens trabecular meshwork for increased aqueous outflow in patients with glaucoma. Also acts on sphincter muscle causing miosis
acts on nicotinic receptors in the sympathetic and parasympathetic nervous system. Only acts on postganglionic receptors in the parasympathetic system. AchE rapidly hydrolyzes this drug in the synaptic cleft
long-acting AchE agent was used in glaucoma treatment as a last resort because of high ocular and sytemic side effects including increased salivation, bradycardia, anorexia, cramps, vomiting and others.
acts on alpha 1 greater than alpha 2 (the radial muscle has alpha 1 receptors). Causes vasoconstriction used for nasal decongestant and pupil dilator.
Beta 1 selective (cardio-selective), Beta1 greater than Beta 2, inotropic (increases contractility). Used for CONGESTIVE HEART FAILURE AND SHOCK
acts on alpha 1 alpha 2, beta 1, beta 2 (limited effects on lung). Used for shock (but decreases renal profulsion) and hypotension
Acts on D1 and D2 (dopamine receptors) greater than beta receptors - and acts the least on alpha receptors. CAN NOT CROSS THE BLOOD BRAIN BARRIER. Primary clinical use is for shock and heart failure. Its derivitave L-Dopa can cross the BBB and is used to treat Parkinson's disease.
fermented from food products such as turkey and promotes serotonin release
similar to norepinephrine. Uses: Shock and acute hypotension, enhances cardiac activity and produces mild vasoconstriction
Prazosin, Terazosin, Doxazosin
alpha 1 selective receptor blockers. Clinical uses: HYPERTENSION AND BENIGN PROSTATIC HYPERTROPHY. Side effects: 1st dose orthostatic hypotension
Can act on both sympathetic and parasympathetic nervous systems. At low doses (cigarette smoking) acts as a stimulant, but at high doses it blocks receptors at the neuromuscular junction and can cause coma and death due to respiratory depression.