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40 Cards in this Set

  • Front
  • Back
What is the intentional use of viruses, bacteria, other microorganisms, or toxins derived from living organisms to cause death or disease in humans, animals, or plants?
Biological warfare.
How are biological warfare agents most effectively delivered?
As an aerosol.
What size aerosolized particles are most efficiently delivered to their target?
1 to 5 microns (μ) in diameter.
What is the target of a BW agent?
The air sacs of the lung.
How may aerosols be delivered?
Via point source (stationary release point, bomblets, or other devices equipped with sprayers) or from a line source (such as a moving vehicle or cruise missile releasing agent).
What destroys most pathogens and toxins?
Heat.
Are nuclear, biological, and chemical weapons/agents, and radiological dispersal devices classified as weapons of mass destruction (WMD)?
Yes.
What are most BW agents incubation periods?
Several days to weeks.
What are the mode of deliveries for BW agents?
Aerosal, food- or waterborne, vectorborne, or injection.
How do BW agents enter the body?
Via the "portals of entry" of naturally occurring infectious diseases.
Name portals of entry.
Respiratory tract, exposed mucosal surfaces, digestive tract, traumatic wounds, superficial abrasions and cuts.
What is the first indication that a BW attack has occurred?
Large numbers of patients simultaneously presenting with a similar disease.
What kind of of blood cultures should be collected to detect bacterial agents?
Aerobic and anaerobic cultures.
Where should cultures and impression smears be taken from?
Involved lymph nodes, sputum, pleural fluid, cerebrospinal fluid (CSF), tissues, or body fluids as clinically indicated.
How much acute serum should be collected for suspected infectious agents?
At least 3 milliliters.
How much acute serum should be collected for suspected intoxications?
At least 20 milliliters.
When should acute serum be collected?
As early as possible after onset of symptoms.
When should convalescent sera be collected from survivors and asymptomatic unit members?
3 to 4 weeks later.
How much postmortem blood should be obtained and submitted as serum and or cells?
Up to 20 milliliters.
Which organs should be sampled?
Lung, mediastinal lymph nodes, spleen, liver, and other tissues as clinically indicated.
How should tissue samples obtained at autopsy be collected?
In multiple aliquots; minimally, one (25-50 grams [gm]) to freeze for microbiology or toxicology testing and one in formalin for histopathology testing should be obtained.
What are the time frames for specimen collection following exposure?
Early post-exposure, clinical, and convalescent/terminal/ postmortem.
Specimens sent rapidly (less than 24 hours) to analytical laboratories require only?
Wet ice or refrigeration at 2° to 8° Celsius (C).
Who should be contacted if the time span increases beyond 24 hours for other shipping requirements such as shipment on dry ice or in liquid nitrogen?
Contact the US Army Medical Research Institute for Infectious Disease (USAMRIID).
Tiger-top tubes that have been centrifuged are preferred over?
Red-top clot tubes with serum removed from the clot.
Blood culture bottles are preferred over?
Citrated blood for bacterial cultures.
What form should be used to maintain a strict chain of custody for every sample/ specimen collected?
Department of the Army (DA) Form 4137 (Evidence/Property Custody Document) or Department of Defense (DD) Form 1911 (Materiel Courier Receipt).
What should be recorded with each change of custody?
Date and time of change.
What is the currently fielded chemical protective equipment used to provide protection against BW agents?
Military protective mask (MCU-2A/P and M40), battle dress overgarment (BDO), Joint service lightweight integrated suit technology (JSLIST), protective gloves, and overboots.
The mask should be worn until?
The "all clear" signal is given.
When may units be directed to conduct unmasking procedures?
If the trailing edge of the hazard area indicates the BW contamination has passed and there are no other indications of BW attacks (example: negative BIDS/LRBSDS results).
Infection control procedures should be reinforced for mass casualty situations with?
Undifferentiated febrile illness following a suspected BW attack.
What should be done with patients until plague and smallpox can be reasonably excluded?
Isolate patients and use respiratory droplet precautions, in addition to standard precautions.
Why should ground ambulances be used first in a contaminated environment?
They are easier to decontaminate than are air evacuation assets.Already contaminated ground and air evacuation assets should be used first. Only commit clean assets if they are required to meet the medical evacuation needs of the command.
What specific control measures must be applied for plague?
Do not evacuate across international borders unless authorized by the theater surgeon. Droplet precautions are added to standard precautions for patients with pneumonic plague until sputum cultures are negative.
What specific control measures must be applied for smallpox?
Do not evacuate across international borders unless authorized by the theater surgeon. Standard, contact, and airborne isolation precautions are to be observed.
What specific control measures must be applied for viral hemorrhagic fevers?
Do not evacuate hemorrhagic fever patients across international borders unless authorized by the theater surgeon. Patients may be evacuated using standard, contact, plus respiratory droplet isolation precautions.
Patient movements will require approval of the destination country, over-flight privileges, and approval of any country where the aircraft will land for servicing or where patients will remain overnight. Countries from which approval is sought are bound by?
Article 37 of the Geneva Conventions for the Amelioration of the Condition of the Wounded and Sick in Armed Forces in the Field of 12 August 1949 to ensure humanitarian treatment to wounded and sick.
What is Executive Order (EO) 13139?
On 30 September 1999, the President of the United States issued Executive Order (EO) 13139, Improving Health Protection of Military Personnel Participating in Particular Military Operations, which outlines the conditions under which investigational new drugs (IND) and off-label pharmaceuticals could be administered to US service members.
When may the President waive the informed consent requirement before IND administration and off-label use of products?
Upon request of the Secretary of Defense if—
Service member informed consent is not feasible. Informed consent is contrary to the best interest of the service member. Obtaining informed consent is not in the best interest of national security.