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41 Cards in this Set

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323. What are the SIX red rashes of childhood (acute, febrile exanthema illnesses)?
(Clue1: maculopapular rash; off-white lesions on buccal mucosa, MMRV vaccine prevents)
(Clue2: maculopapular rash starting on face moving to foot; MMRV prevents)
(Clue3: scarlatina rash post pharyngitis)
(Clue4: vesicular rash, moderate pain)
(Clue5: maculopapular “slapped face” appearance in a young child)
(Clue6: maculopapular rash and systemic Dz in immunocompromised pt)
Measles
Rubella
Scarlet fever (GAS)
Chicken pox (VZV)
Parvovirus B19
HHV-6
324. Worldwide rubella infection, with only human reservoirs known this infectious agent is a
RNA togavirus
325. >95% seropositive after MMRV if >12mos age and lifelong protection against rubella is conferred with?
Single dose
326. Cause of single or multiple scaly and/or crusted patches and/or plaques, affecting the scalp or beard area +/- inflammation.
Dermatophytes
327. KOH prep of scales from the scalp and plucked hairs from cutaneous mycoses may reveal?
hyphae and spores
328. Most common cause of cutaneous mycoses
Trichophyton spp.
329. Common cause of cutaneous mycosis with animal contact
Microsporum spp.
330. Oral DOC of cutaneous mycoses
itraconazole
331. Topical DOC of cutaneous mycoses
terbinafine
332. Dz w/ subcutaenous lesions w/ slow spread by lymphatic system producing nodules in a gardener, or from rose-thorn injury.
Sporotrichosis
333. Cause of subcutaenous lesions w/ slow spread by lymphatic system producing nodules in a gardener, or from rose-thorn injury.
Sporothrix schenckii
334. Dimorphic fungus that grows at 37°C as cigar-shaped yeast, and produces septate hyphae and conidia (in daisy arrangement) at 25°C is
Sporothrix schenckii
335. DOC of sporotrchosis
itraconazole.
336. Cause of deeper and wider lesions with interconnecting subcutaneous abscesses arising from infection of several neighboring hair follicles, in young children.
Staphylococcus aureus (Curbuncle)
337. Cause of superficial pustules progressing to erosions covered by honey-colored crusts, surrounded by erythematous halo, in young children.
Staphylococcus aureus >> Streptococcus pyogenes (non- bullous impetigo)
338. Dz characterized by bullae and denuded areas after the blisters rupture, covered by thin, varnish-like light brown crusts; regional lymphadenopathy, in children.
DOC if lab: gram stain and culture of pus or base of the lesions yields GPC in chains.
DOC if lab: gram stain and culture of pus or base of the lesions yields GPC in clusters.
Bullous impetigo
Penicillin G
Nafcillin
339. mecA (SCC) genes which encode PBP2a, w/ low affinity for β-lactams; confers resistance in Staphylococcus aureus against what?
Nafcillin
340. Cause of spreading (butterfly-wing) erythema on the face that responds to empirical penicillin.
Streptococcus pyogenes (Erysipelas)
341. Cause of severe pain on his knee w/ site of injury is tender and erythematous. Blood culture may yield?
Streptococcus pyogenes. (Cellulitis)
342. What is the microbial factor that promotes degradation of C3b by binding to factor H, the serum β globulin factor
M protein
343. Other epidemiologically linked or risk-associated causes of cellulitis are:
Clue1: cat/dog bite. What?
Clue2: Salt water exposure. What?
Clue3: Fresh water exposure. What?
Clue4: Neutropenia. What?
Clue5: Human bite. What?
Pasteurella multocida / Capnocytophaga canimorous
Vibrio vulnificus
Aeromonas hydrophila
Pseudomonas aeruginosa
Eikenella corrodens
344. Most likely cause of fever/chills/ night sweats, localizing pain/tenderness or swelling/erythema (lab: ↑ESR, ↑CRP; ↑WBC w/ left shift. Radiology: periosteal elevation.) is
Staphylococcus aureus (Osteomyelitis)
345. Major antiphagocytic virulence factor of drug-resistant organism that causes osteomyelitis is
protein A
346. Major neutrophil-damaging virulence factor of drug- resistant organism that causes osteomyelitis is
Penton-Valentine leukocydin
347. Cause of vertebral, sternoclavicular or pelvic bone infections (in pt w/ IVDU) or osteochondritis of foot (following penetrating injuries through tennis shoes)?
Pseudomonas aeruginosa
348. Cause of osteomyelitis in pt w/ underlying sickle cell Dz; blood culture +)?
Salmonella typhimurium
349. Cause of chronic, vertebral osteomyelitis (blood culture negative)?
Mycobacterium tuberculosis
350. Cause of osteomyelitis in pt. w/ hx of cat bites; GNSR; fastidious growth of wound culture?
Pasteurella multocida
351. Cause of fever, chills, malaise, joint pain, swelling. PE: tenderness, erythema, heat, swelling, decreased ROM. CBC: leukocytosis w/ neutrophils predominating; joint aspirate: no crystals.
Clue1: sexually active; BLCx (-); responds to ceftriaxone Think of other pathogens (BLCx negative):
Clue2: Rheumatoid arthritis?
Clue3: IVDU?
Clue4: Unpasteurized dairy products
Clue5: Diabetes
Septic arthritis
Neisseria gonorrhoeae
S. aureus
S. aureus, P. aeruginosa
Brucella spp.
S. agalactiae (GBS)
352. Dz is characterized by arthritis in up to 6 joints (especially knees, feet), low back pain/stiffness, irritable eyes w/ or w/o redness, conjunctivitis, iritis, malaise. TOW?
Caused by:
Clue1: sexually acquired
Clue2: non-sexually acquired
Reactive arthritis
C. trachomatis, N. gonorrhoeae
Campylobacter, Salmonella
353. Cause of bacteremia in neutopenic pts with central line or pts with prosthetic devices and catheters; blood culture (+)
Staphylococcus epidermidis
354. Cause of intraabdominal abscess w/ putrid pus; anaerobic bacteremia in pt with trauma or solid GI tumor?
Bacteroides fragilis.
355. A woman with obstetric infection has fever > 102oF, SBP < 90; diffuse sunburn-like rash or desquamation of palms and soles; multisystem Sx/Sns; vomiting, and diarrhea; BLCx (-). TOW?
Staphylococcal Toxic shock Syndrome
356. What is the toxin associated with staphylococcal toxic shock syndrome?
TSST-1 (a superantigen)
357. Cause of severe, watery diarrhea in a woman with toxic shock syndrome?
Enterotoxin (coregulated with TSST-1)
358. Cause of toxic shock syndrome, which responds to vancomycin and clindamycin?
MRSA
359. Hx of fever > 38.9oC, SBP < 90 ; diffuse sunburn-like rash or desquamation of palms and soles, in a man w/ necrotizing fasciitis or myositis; multisystem involvement; BLCx (+). TOW?
Streptococcal toxic shock syndrome
360. What is the toxin associated with streptococcal toxic shock syndrome?
SpeA (superantigen)
361. DOC for streptococcal toxic shock syndrome
PenG + clindamycin
362. Hx of fever, chills, and hypotension. Blood culture yields a GNR, oxidase (-), lactose fermenting organism on MacConkey agar. Immunological mediators of sepsis.
IL-1 and TNF
391. Hx of sudden fever ≥ 39°C , homogeneous vesiculo- pustular rash (unlike common viral exanthems) in multiple pts is caused by
Variolla major virus (small pox)