Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
343 Cards in this Set
- Front
- Back
|
What is the generic of Aricept
|
Donepezil
|
|
|
What is MOA of Aricept
|
Acetylcholineserase inhibitor (increase AcH by inhibiting its breakdown)
|
|
|
What is Donepezil approved for treatment of
|
MILD to SEVERE alzheimers dementia
ONLY one with indications for ALL types |
|
|
What is the generic of Zestril
|
Lisinopril
|
|
|
What is the generic of Prinivil
|
Lisinopril
|
|
|
What is the generic of Vasotec
|
Enalapril
|
|
|
What is the generic of Altace
|
Ramipril
|
|
|
What is the generic of Lotensin
|
Benazepril
|
|
|
What are contraindications for ACE inhibitors
|
Avoid is K >5
Avoid with angioedema (any pt) Bilateral artery renal stenosis Pregnancy D/C if Scr >0.3 |
|
|
What are counseling pts (SE)
|
Non-productive cough
Dizziness Avoid salt substitutes (since increase K |
|
|
What is Flomax
|
Tamsulosin
|
|
|
What is MOA of Flomax
|
Selective Alpha 1 antagoinst, in the prostate leads to relaxation of smooth muscle in the bladder neck, and prostate, which improved urinary flow
|
|
|
Couseling pt for patients on Tamsuloxin (Flomax)
|
May decrease BP, tell eye doctor, if getting cataract surgery
|
|
|
What is generic of Catapres
|
Clonidine
|
|
|
What is MOA of Catapres
|
Alpha 2 agoinst (stimulates alpha 2 receptors to DECREASE NE outflow (decrease PVR, HR)
|
|
|
Counseling points for Catapres
|
Risk of hypotension
avoid abrupt withdrawl |
|
|
What is the generic of Namenda
|
Memantine
|
|
|
What is MOA of Namenda
|
Blocking NMDA receptors (inhibits glutamate (an excitory NT)
|
|
|
Role of Namenda
|
moderate to SEVERE ALzheimers
|
|
|
What is generic of Lidoderm
|
Lidocaine
|
|
|
What is MOA of Lidoderm
|
inhbits depolarizations (decreases membrane permeability to sodium
|
|
|
SE of Lidoderm patch
|
mainly topical (ithcing depigmentation)
|
|
|
Couseling pts with Lidoderm
|
may use up to 3 patches on ONE area, leave on for up to 12 hours in any 24 hours period
|
|
|
Can you cut Lidoderm patch
|
YES, one of the few that can be cut!!
|
|
|
What is the generic of Diovan
|
Valsartan
|
|
|
What is MOA of Diovan
|
ARB (blocks ATII type 1 receptors, preventings vasoconstrtions, aldosterone release)
|
|
|
What is generic of Cozzar
|
Losartan
|
|
|
What is generic of Benicar
|
Olmesartan
|
|
|
What is generic of Avapro
|
Irbesartan
|
|
|
Contraindications of ARB's
|
same as ACE
Pregnancy Bilateral renal artery stenosis, Hyperkalemia |
|
|
Couseling pts of ARBs
|
hypotension, monitoring K, Scr, and avoid salt substitutes
|
|
|
What is generic of Lanoxin
|
Digoxin
|
|
|
What is MOA of Digoxin
|
increases intracelluar calcium to improve contractility
|
|
|
Diogoxin is narrow TI drug, what is recommend goal
|
0.5-0.8 for CHF
|
|
|
What are signs/symptoms of Digoxin toxicity
|
Halos around lights, N/V and EKG changes
|
|
|
What is the reversal agents to Lanoxin
|
Digibind
|
|
|
Do you dose adjust with Digoxin
|
YES--renally eliminated
|
|
|
What is generic of Amoxil, Trimox
|
Amoxicillin
|
|
|
What is MOA
|
Beta-Lactam inhbits bacteral cell wall syntheisis by inhibits transpeptidase
bacterialcidal |
|
|
Main uses of AMOXCILLIN
|
Otitis Media, Sinusitis dental procedures
|
|
|
Can you give amoxillin in pregnancy
|
YES, pregnancy B
|
|
|
What is generic of Augmentin
|
Amoxcillin/Clavulanate
|
|
|
Do you need Augmentin for Step infections
|
NO---Streptococcus do NOT make beta-lactamases
|
|
|
What is generic of Tylenol #3
|
APAP/Codeine
|
|
|
What is schedule of T3
|
Class III
or CV for solution |
|
|
What is MOA of T3
|
binds to mu-opioid reecptors
|
|
|
Why is T3 not a very potent anagesic
|
only 20-30% will get metabolized to morphine (codeine is pro-drug requring CYP2D6
|
|
|
The T3 corresponds to how many mg of codeine
|
30mg
|
|
|
What is T2
|
15 mg
|
|
|
What is T4
|
60 mg
for each number increase codeine doubles |
|
|
What is generic of Detrol LA
|
Tolerodine
|
|
|
What is MOA of Detrol LA
|
Anti-cholingeric
(atagonists urinary muscarinic recpetors that control muscle contraction |
|
|
What are se of Detrol LA
|
Anticholinerics SE
Burry visition, drug mouth, unirary rentention constipation |
|
|
What is the generic of Spirivia
|
Tiotropium
|
|
|
What is MOA of Spirivia
|
inhibits AcH resulting in broncodilation
|
|
|
Tiotropium is once daily, how often is ipratropium
|
4x
|
|
|
What is generic of Atrovent
|
Ipratropium
|
|
|
Max dose of Atrovent
|
12 puffs in 24 hrs
|
|
|
Should you avoid Tiotropium and Ipratropium
|
YES--both anticholingerics
|
|
|
What is MOA of Coumadi
|
inhibits activtion of vitamin K by VKOR (inhibit activton of 2, 7, 9, 10 and protein C and S
|
|
|
Coumadin is a narrow therpeutic index drug, what are the main ways it interacts with other drugs
|
inhibits CYP2C9
(Bactrim, Amiodarone) |
|
|
What pregnancy class is coumadin
|
X----very BAD
|
|
|
What is the generic of Neurontin
|
Gabapentin
|
|
|
What is MOA of Neurontin
|
Modulates activity of Na/Gaba
|
|
|
What is generic of Lyrica
|
pregabalin
|
|
|
What is controll status of Lyrica
|
CV
|
|
|
Gabapentin/Pregablin is renally adjusted
|
YES
|
|
|
What is generic of Lamictal
|
Lamotrigine
|
|
|
What is MOA of Lamotrigine
|
Blocks Na+
|
|
|
What is couseling pt with Lamotrigine
|
monitor for rash at least the first 8 wks of thearpy
|
|
|
What is MAJOR DI with lamotrigine
|
valproic acid
|
|
|
What is the generic of Wellbutrin
|
Bupropion
|
|
|
What is generic of Zyban
|
Buproprion (smoking cessation
|
|
|
What is MAJOR contraindication of Buproption
|
seizures and eating disotrders
|
|
|
What is MOA of Bupropion
|
inhibits reuptake of DA and NE (increases)
|
|
|
What Antidepressant does NOT cause sexual dysdunction
|
bupropion
|
|
|
What are the brand names of Albuterol
|
ProAir
Ventolin Proventil |
|
|
What is MOA of Albuterol
|
B2 agoinst (binds to recpetors on broncial smooth muscle causing relaxation
|
|
|
What is generic of Foasmax
|
Alendronate
|
|
|
What is MOA of Fosamax
|
Bisphophosnate
Inhibits osteoclast activity |
|
|
Why must Fosamax be taken with 8oz of water 30 minutes before food/drink and remain upright for 30 minutes
|
risk for esophagitits and poor absorption
|
|
|
What must also be supplemented with Fosamax
|
Calcium/Vitamin D
|
|
|
What CrCl should Bisphophnates be avoided in
|
CrCl <35
|
|
|
What is the generic of Zyloprim
|
Allopurinol
|
|
|
What is MOA of Allopurinol
|
Xanthine Oxidase inhibitor
(inhibits uric acid syntheisis) |
|
|
What is role of Allopurinol
|
only use for prevention of gout
|
|
|
What is a MAJOR DI with Allopurinol
|
Azathioprine
causes major bone marrow suppresion |
|
|
What do you monitor for with Allopuriol
|
skin rash/hypersenstivity
|
|
|
What is generic of Xanax
|
Alprazolam
|
|
|
What is MOA of Xanax (Alprazolam)
|
GABA agoinst
|
|
|
What length of time should Xanax no longer be abruptly discontinued
|
>3-4 weeks will cause withdrawl
|
|
|
What should you counsel to avoid use with
|
alcohol
|
|
|
What is pregnancy category of Xanax (Alprazolam)
|
Pregnancy D
|
|
|
What is generic of Elavil
|
Amitriptyline
|
|
|
What is MOA of Elavil
|
TCA (inhibits reuptake of 5HT and NE
|
|
|
What are common SE of Elavil
|
Anticholingeric (blurry vision, dry mouth, constipation, urinary retention)
|
|
|
Is Elavil a Beer's List medication
|
YES
|
|
|
What is generic of Norvasc and Class
|
Amlodipine (Dihydropyridine CCB)
|
|
|
What is MOA of Norvasc
|
Dihydropridine CCB (blocks Ca+ entry into vascular smooth muscle leading to vasodilation
|
|
|
What is the preferred CCB in ESRD/Dialysis
|
Amlopdine (nor renally elimiated)
|
|
|
What is generic of Lotrel
|
Amlodpine/Benazepril
|
|
|
What is MOA Lotrel (Amlodpine/Benazepril)
|
ACE I and CCB
|
|
|
What is generic of Abilify
|
Aripiprazole
|
|
|
What MOA of Abilify
|
Atypical antipsyychotic
Partial agoinst of D2, and 5HT receptors |
|
|
How is Abilify supplied
|
Tablet, ODT, oral solution, IM
|
|
|
What should you monitor for with Abilify
|
LIpids, Glucose, acathisia
|
|
|
What is generic of Tenormin
|
Atenolol
|
|
|
What is MOA of Tenormin
|
Selective Beta 1 Blocker
Blocks binding of NE to receptors in heart and Kindey, |
|
|
Is Tenormin FDA approved for HF
|
NO
|
|
|
What should you monitor for with Tenormin
|
BP, HR
|
|
|
Tenormin (Atenolol) is a hydrophilic beta blockers and thus
|
renally eliminated
|
|
|
What disease states should Beta blockers be used in caution with
|
PVD or claudicaiton
|
|
|
How much can Lipitor (Atrovastatin) lower LDL cholesterol
|
50-55%
|
|
|
What should you moinitor while on Lipitor
|
LFT (hold >3x ULN), S/S myopathy, Rhabo, Lipids
|
|
|
Drug intearctions with Lipitor
|
Drugs that inhibit CYP3A4 (Azoles, Ery-Tab, Clarthromiycin)
PI---ok in low dose 10mg |
|
|
What is Pregnancy Cateory of Lipitor
|
X
|
|
|
What is gneric of Zmax or Zithromax
|
Azithromycin
|
|
|
What is drug class of Aithromycin
|
Macrolide
Binds to 50S ribosomal subnits and inhibits protein synthesis |
|
|
How is Azithromycin supplied
|
Tablet, Suspension, IV
|
|
|
What is main role of Macrolides
|
Chalmydia, MAC, URI
|
|
|
Can you replace Zpak for clarithromycin in H Pylori
|
NO
|
|
|
Does ZPak have any drug interactions
|
NO---think Clarithromycin
|
|
|
What is generic of Suboxone
|
Buprenoprhine/Naloxone
|
|
|
What is control of Suboxone
|
CIII
|
|
|
Why is Suboxone formulated with Naloxone
|
so if try to use by IV, naloxone would antagoinst opioid receptors
|
|
|
How is Suboxone taken
|
sublingually
|
|
|
What is role of Suboxone
|
maintenance treatment of opioid dependence
|
|
|
Who can prescribed suboxone
|
only prescribeers with an X
|
|
|
What eye ointment is used on all babies at birth
|
Erythromycin
prevent opthalmia neonatorum |
|
|
What is generic of Soma
|
Carisoprodol
|
|
|
What is MOA of Soma
|
Skeletal muscle relaxant
|
|
|
What is generic of Coreg
|
Carvediolol
|
|
|
What is MOA of Coreg
|
Non-selective BB, and alpha 1 blocker
|
|
|
Carvediolol IR is dose BID, what CR is dosed
|
once daily
|
|
|
What is starting dose of Carvediolol for heart failure
|
3.125 mg BID, and tirtrate every 1-2 weeks to avoid causing decompensations
|
|
|
What is goal tirtation of Carvediolol in HF
|
25 mg BID
|
|
|
What should you mointor on Carvediolol
|
HR, BP
|
|
|
What is generic of Celebrex
|
Celecoxib
|
|
|
What is MOA of Celebrax
|
Selective COX-2 inhibitior
|
|
|
What allergy should Celebrex be avoided in
|
SULFA allergy
|
|
|
Who should Celebrex be used in caution with
|
CV disease, HF, HTN, GI or renal disease
|
|
|
Keflex is only available as
|
oral formulation
|
|
|
What is MOA/Drug class of Keflex
|
Beta-Lactam, 1st generation Cephalosporin
|
|
|
What is MOA of Cipo (Ciprofloxacin)
|
Floroquinolone
Inhibits DNA gyrase preventing DNA replication and repair |
|
|
What are 2 Floroquinolones that cover Pseduomonas
|
Levofloxacin, Ciprofloxacin
|
|
|
When do you renal dose Fluorquinolones
|
CrCl <50
|
|
|
What is major couseling point with floroquinolones
|
avoids di or tri-valent Cations (Ca+, Mg)
|
|
|
Should you avoid flouoquinolones in pregancy
|
YES, C
|
|
|
What is generic of Celexa
|
Citalopram
|
|
|
How long does Celexa take before efficacy
|
3-4 weeks
|
|
|
What SSRI has the least DI
|
Citalopram
|
|
|
Is sexual dysfunction a common problem with SSRI
|
YES
|
|
|
Should you avoid aburpt DC of all SSRI
|
YES
|
|
|
What is generic of Klonopin
|
Clonazepam
|
|
|
What is generic of Plavix
|
Clopidogrel
|
|
|
What is MOA of Plavix
|
Anti-platlet
Blocks ADP on prevetion, preventing platlet aggregation |
|
|
What is monitoring with Plavix
|
signs/symptoms of bleeding
|
|
|
Plavix is a pro-drug what is problems
|
DI---especially PPI (omeprazole/lansoprazole) or any drugs that inhibit CYP2C19
|
|
|
What should patient also get with getting stent in addition to Plavix
|
ASA (12 moths DES)
1 month for BMS |
|
|
How long should plavix be stopped prior to CABG
|
5 days becuase increase risk of bleeding
|
|
|
What is generic of Premarin
|
Conjugated Estrogen
|
|
|
What is role of Premarin
|
hot flash control, and symptoms of menopauses
|
|
|
Conjugated estrogens should be use at the lowest dose and shortest duration, what are contraindications
|
VTE, vascular disease, hx of breast cancer
|
|
|
Flexeril (Cyclobenzaprine) MOA
|
Skeletal muscle relaxant, ALSO inhibitts 5HT NE uptake
|
|
|
Cyclobenzabrine is sturucally similar to TCA, so increase risk for
|
serotonin syndrome
|
|
|
What are common SE of Cycloenzprine
|
Sedation, drowiness--avoid alcohol
|
|
|
What is generic of Adderall
|
Dextoamphetamine
|
|
|
WHat is MOA of Adderall
|
Stimulant (Blocks reuptake of NE/DA, and stimulates CNS
|
|
|
What is monitoring for Adderall
|
appetits, weight, BP, HR
|
|
|
What is the generic of Vibramycin?
|
Doxycycline
|
|
|
What is the generic of Doryx?
|
Doxycycline
|
|
|
WHat is MOA of Doxycycline
|
Tetracycline
inhbits 30S ribosome, inhibiting protein synthesis |
|
|
Can Doxycycline be used for MRSA infections
|
YES, outpatients
|
|
|
What age must children be to use tetracycline and why NOT used in pregnancy!
|
>8 yrs becuase causes yellowing of teeth
|
|
|
What are the MAJOR DI with Tetracycline
|
Chelate avoid taking with antacids, Ca, Ma, iron (decrease absoprtion)
|
|
|
What is generic of Yaz
|
Dorspirenone/EE
|
|
|
What drug class if YAZ
|
COC
|
|
|
Who should avoid Combined oral contraceptives
|
pts who smoke and >35, history of DVT, or hypercoagulale
|
|
|
WHat is Drospirenone derived from
|
Sprionolactone (anti-androgeneic) watch out for HyperKalemia
|
|
|
What is generic of Cymbalta
|
Duloxetine
|
|
|
WHat is MOA
|
SNRI
|
|
|
What are role of Cymbalta in treatment
|
GAD, Depression, neuropathic pain, fibromyalgia muscleskeltal pain
|
|
|
What is Monitoring of Cymbatla
|
BP (SNRI)
|
|
|
What are major DI with PPI
|
avoid with itraconazole, ketoconazole, and atazanavir
|
|
|
What is generic of Lunesta
|
Eszopiclone
|
|
|
What is drug class of Eszopicolone (Lunesta)
|
Gaba like agoinst
|
|
|
What is couseling points with Lunesta
|
unpleasant tase, avoid other CNS deperssants
|
|
|
What is generic of Zetia
|
Ezetimibe
|
|
|
What is MOA of Zetia
|
cholesterol absorption inhibitor
|
|
|
What is negative to using Zetia
|
no data available to support decreased mortaility
|
|
|
What are the brand names of Fenofibrate
|
Tricor, Triglide, Fenoglide, Lofibra
|
|
|
What is MOA of Fenofibrate
|
Fibric acid dervative or PPAR-alpha
|
|
|
What are CONS of Fenfibrate
|
NO mortality data supporting use
|
|
|
Does Fenofibrate have drug interactions with statins like gemfibrozil
|
NO
|
|
|
What is generic of Allegra
|
Fexofenadine
|
|
|
What is MOA of Allegra
|
H1 antagoinst (2nd generation)
does NOT cross the BBB, so minial sedation |
|
|
What is generic of Diflucan
|
Fluconazole
|
|
|
What is MOA of Diflucan
|
Inhbits Ergosterol synthesis
|
|
|
What is the main role if Diflucan
|
vaginal yeast infections (1x dose)
|
|
|
What are MAJOR DI with fluconazole
|
CYP2C9, and CYP3A4
|
|
|
What does Prozac a strong inhibitor of, and why problem
|
CYP2D6, avoid use with atomoxetine, tramadol, tamoxifen
|
|
|
What is generic of Flovent HFA
|
Fluticasone
|
|
|
What is improtant couseling point prior to use of Flonase (Fluticasone)
|
Clear Nasal passages before dose is given
|
|
|
What is generic of Advair
|
Fluticasone/Salmeterol
|
|
|
What is MOA/Drug Class
|
Inhaled Corticosteriod/LABA
|
|
|
What vitamin is Folic Acid
|
B9 (water soluble vitamin)
|
|
|
What is main role of folic acid
|
pregancy prevents spina bifida
|
|
|
What is MOA of Lasix
|
Inhibits Na/K+ symporter in the Loop of Henle
|
|
|
What do you monitor on Lasix
|
BP, Electrolytes (K, Mg, Ca, Na)
|
|
|
Does Gabapentin require renal dosage adjustment
|
YES
|
|
|
What is generic of Glynase or Diabetea, Micronase, PresTab
|
Glyburide
|
|
|
What is MOA of Glynase (Glybrudie)
|
Sulfonylurea (Binds to the Sulfonlurea receptor on pancreatic beta stimuates and stimulates glucose INDEPENDENT insulin secretion
|
|
|
What are adverse effect of Diabeta
|
hypoglycemia, weight gain
|
|
|
What CrCL should you avoid Glyburide
|
<50ml
|
|
|
What is generic of Cheratussin AC
|
Guaifensein/Codeine
|
|
|
What is Class/MOA
|
Expectorant/Cough Suppresant
|
|
|
Codeine plays the role as cough suppressant, what cough is it not recommended
|
productive
|
|
|
What is generic of Microzide or Esidrix
|
HCTZ
|
|
|
What is MOA of Microzide (HCTZ)
|
Inhibits Na/Cl symporter in DCT
|
|
|
Who should avoid be treated with HCTZ
|
patients with gout (increase uric acid levels)
|
|
|
What is generic of Lortab/Vicodin
|
Hydocodone/APAP
|
|
|
What control level is Vicodin
|
CIII
|
|
|
What is Hydrocodone metabolized to
|
Hydromorphone (Dilaudid)
|
|
|
What is generic of Ismo, MonoKet
|
Isosorbide Mononitrate
|
|
|
What is MOA of Imdur/Ismo
|
Vasodilator
relaxes smooth smooth (reduces preload) |
|
|
What formulation of Isosorbide is dosed BID
|
Mononitrate
|
|
|
What formulation is once daily
|
Imdur
|
|
|
SE of Isosorbide
|
Hypotension, HA, dizzines
|
|
|
WHat is MAJOR DI with Isosorbide
|
not to use with PDE-5 inhibitors because of profound risk for hypotension/shock
|
|
|
What is generic of Xalatan
|
Latanoprost
|
|
|
What is MOA of Xalatan
|
Antiglucoma/prostaglandin analog
|
|
|
Xalatan is eye drop applied once daily for glaucoma, what are SE
|
changes color of the eye, eyelid and/or eyelashes
|
|
|
What is generic of Synthroid, LEvoxyl
|
Levothyroxine
|
|
|
What is MOA of Levoxyl
|
Synthetic T4
|
|
|
What is monitoring of Levoxyl
|
TSH after 6-8 weeks after starting or DOSE change
|
|
|
Levoxyl is ideally taken once daily on empty stomach prior to breakfast, however what should they always avoid
|
Ca/Mg Ir, and binds
|
|
|
What is generic of Vynase
|
Lisdexafetamine
|
|
|
What is MOA of Vyvanse
|
Stimulate (stimulates release of NE and DA)
|
|
|
What is generic of Zestoretic
|
Lisinopril/HCTZ
|
|
|
What is generic of Ativan
|
Lorazepam
|
|
|
Ativan is benzodiazepine, what are role for treatment
|
Anxeity, status eplieticus, alcohol withdrawl
|
|
|
What is generic of Hyzaar
|
Lorsartan/HCTZ
|
|
|
What is generic of Mevacor
|
Lovastatin
|
|
|
What are the big drug interactions with Mevacor
|
major CYP3A4 substrate, interaction with inhibitors
Verapamil, amiodarone, PI, Azole/Ery-tab, Clarthromycin, |
|
|
What is generic of Antivert
|
Meclizine
|
|
|
What is MOA of Antivert
|
1st generic antihistamine/antimetic
|
|
|
What is role of meclizine
|
motion sickness, dizziness, morning sickness
|
|
|
What is generic of Mobic
|
Meloxicam
|
|
|
What MOA of Mobic
|
NSAID (more cox 2 selective)
|
|
|
How often is Mobic doses
|
ONCE daily
|
|
|
What do you monitor on Mobic
|
BP, Renal function, Gastritics,
|
|
|
Who should NOT take NSAID
|
prior ulcers, renal failure, HF, and uncontrolled HTN, pregancy (especially 3rd trimester)
|
|
|
What is generic of Glucophage, Fortamet
|
Metformin
|
|
|
What is MOA of Glucophage
|
Biguanide, inhibits hepatic glucose production, and improves insulin senstivity
|
|
|
What are contraindications of Glucophage
|
Cr 1.5 or greater in men and Cr 1.4 or greater in women, and IODINATED contrast
|
|
|
WHat is generic of Concerta
|
Methylphenidate
|
|
|
What is MOA of Concerta
|
Stimulate (increase DA/NE
|
|
|
What is generic of Medrol
|
Methylprednisolone
|
|
|
What are SE of Medrol
|
Edema, hyperglycemia, osteoprosis, cataracts, ulcers, impaired wound healing, CNS stimulation, avascular necrosis (bone breaking off )
|
|
|
What is generic of Toprol
|
Metoprolol Succinate
|
|
|
What is generic of Lopressor
|
Metoprolol Tartarte
|
|
|
What is generic of Nasonex
|
Mometasone
|
|
|
What is generic of Mobic
|
Meloxicam
|
|
|
What is MOA
|
NSAID (COX inhibitor) more seleective COX-2 inhibition
|
|
|
What is generic of Singulair
|
Montelukast
|
|
|
What is MOA of Singulair
|
Luekotriene receptor antagoinst
|
|
|
Singular comes in regular and chewable tablets
|
YES
|
|
|
What age can peds start Singulair
|
6 months, and 12 months
|
|
|
What is generic of Niaspan
|
Niacin
|
|
|
What is the major SE of Niaspan and how to treat
|
Flushing, decrease with taking 325 mg ASA 30 minutes before doase
|
|
|
What is Adverse Effects/Cautions with using Niaspan
|
Increases uric acid, and glucose levels, and monitor LFTs
|
|
|
What is generic of Zyprexa
|
Olanzapine
|
|
|
What is MOA of Zyprexa
|
Dopamine and 5HT antagonist, and also antagoinst activity on histamine
|
|
|
What are adverse effects of Zyprexa
|
WEIGHT, cardio-metabolic effect
|
|
|
What is generic of Benicar
|
Olmesartan
|
|
|
What is MOA of Benicar
|
ARB, inhbit ATII receptor 1
|
|
|
What is generic of Benicar HCT
|
Olmesartan/HCTZ (ACE/ARB)
|
|
|
What is the generic of Lovaza
|
Omega 3 fatty acid
|
|
|
What allegry should pts avoid Lovaza
|
Shellfish/fish
|
|
|
What is generic of Tamiflu
|
Oseltamivir
|
|
|
What is MOA of Oseltamivir
|
Antiviral (neurmainidase inhibitor)
|
|
|
Tamiflu treats both influenza A and B, and is effective for both treatment/prophylaxis if begun within - hours of onset/exposure
|
48 hours
|
|
|
Treatment of Tamiflu duration
|
5 days
|
|
|
What is prophylaxis of Tamiflu duration
|
10 days
|
|
|
What is generic of Oxycontin
|
Oxycodone ER (IN means extended release)
|
|
|
What is generic of Percocet
|
Oxycodone/APAP
|
|
|
What is controlled status of Percocet/Endocet/Tylox
|
CII
|
|
|
What generic of Paxil
|
Paroxetine
|
|
|
Paxil is a strong inhibitor of CYP2D6 so caution with the following medications
|
Atomoxetine, tramadol, and tamoxifen
|
|
|
What is the only SSRI that is preganacy category D
|
Paxil
|
|
|
What is generic of Actos
|
Pioglitazone
|
|
|
What is MOA of Actos
|
TZD (PPAR-Gamma)
|
|
|
What are cautions/adverse effects of Actos
|
Peripheral edema, weight gain, and containdicated in Class III/IV HF, and increase fracture risk
|
|
|
What is generic of Pravachol
|
Pravastatin
|
|
|
What is generic of Phenergan
|
Promethazine
|
|
|
What is drug class of Phenergan
|
Antiemetic/1st generic antihistamine
|
|
|
How can Phenergan be given
|
ORALLY (also elixir), IM, IV
NOT SUBQ |
|
|
What are SE of Phenergan
|
sedation/drowsiness, and CNS depression, pseduoparkinsonism, and anticholingeric SE
|
|
|
What is generic of Seroquel
|
Quetiapine
|
|
|
What is MOA of Seroquel
|
Atypical antipsychotic
antagoinism of 5HT/DA |
|
|
Role of Seroquel
|
Bipolar, SCZ, and ICU delirium
|
|
|
What is BBW of Seroquel as well as other antipsychotics
|
warning use in elderly with dementia increases mortality
|
|
|
What is generic of Aciphex
|
Rabeprazole
|
|
|
What is MOA of Aciphex
|
PPI (inhibits H/K_ ATPase pump0
|
|
|
What is generic of Evista
|
Raloxifene
|
|
|
What is MOA of Evista
|
Selective estrogen receptor modulators (agoinst of estrogen receptor on bones (ANTAGONIST on uterus/breast)
|
|
|
Raloxifene (Evista) can be used for osteoporosis, but also commonly used for what
|
decrease risk of invasive breast cancer
|
|
|
What are cautions/contraindications with use of Evista
|
History of VTE/Breast cancer
|
|
|
What is generic of Altace
|
Ramipril
|
|
|
What is generic of Zantac and MOA
|
Rantidine H2 antagonist
|
|
|
What happends during M phase.
|
M phase (cell division), mitosis and cytokinesis occur, producing two daughter cells.
|
|
|
What is generic of Actonel
|
Risdronate
|
|
|
What is MOA Actonel
|
Biphosphonate
Inhibits osteoclast activity |
|
|
What is generic of Crestor
|
Rousvastatin
|
|
|
What is generic of Sertraline
|
Zoloft
|
|
|
What is generic of Vigara
|
Sildenafil
|
|
|
What is MOA of Viagra
|
PDE 5 inhibits
|
|
|
Viagra is contraidicted in with what other day
|
nitrates!!
|
|
|
What is generic of Zocor
|
Simvastatin
|
|
|
What is MOA of Zocor
|
HMG co reductase inhibit
|
|
|
Zocor should be avoided with what other drug
|
PI, verampil, amiodarone, gemfibrozil, Azoles, Ery, Clarithromycin
|
|
|
What is generic of Vytorin
|
Simvastatin/Ezetimibe
|
|
|
What is generic of Januvia
|
Sitagliptin
|
|
|
WHat is MOA Januvia
|
DDP-IV inhibitor
|
|
|
Bactrim MOA
|
Inhibits folic acid synthesis, and DHFR
|
|
|
Bactrim is DOC in what type if HIV pts
|
PCP
|
|
|
Should Bactrim be avoided in pts with G6PD
|
YES can cause hemolysis and jaundice, fatigue
|
|
|
What is generic of Cilalis
|
Tadalafil
|
|
|
What PDE-5 inhibitor has a long-half life
|
Cilais/Tadalfil
|
|
|
What is generic of Ultram
|
Tramadol
|
|
|
Should tramadol be avoided in pts with seizures?
|
YES
|
|
|
What is MOA Trazadone
|
Serotoin reuptake inhibtior
|
|
|
What is generic of Maxzide/DYazide
|
Triamterene/HCTZ
|
|
|
What is MOA Maxzide/Dyazide
|
Thiazide and K+ sparring diuretic
|
|
|
What is generic of Valtrex
|
Valacyclovir
|
|
|
What is MOA Valtrex
|
inhibit viral DNA synthesis
|
|
|
Valtrex is a progdrug of
|
Acyclovir
|
|
|
What is generic of Diovan HCT
|
Valsartan/HCTZ
|
|
|
What is generic of Calan SR
|
Verapamil
|
|
|
What is MOA of Calan SR
|
CCB (NON-dihydropyridine)
|
|
|
Why is Verapamil contraindicated in HF
|
decrease inotropy
|
|
|
What are SE of Verapamil
|
constipation, peripheral edema
|
|
|
Are there drug interaction with Verapamil, why
|
substrate and inhibitor of CYP3A4
|
