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100 Cards in this Set
- Front
- Back
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Gram +ves are generally... |
Staph
Strep Enterococcus Clostridium Listeria |
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Gram negatives are generally...
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not one of the gram positives...
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What are some hydrophilic Abx
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B lactams
AG Glycopeptides Daptomycin Colistin |
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What are some lipophilic abx
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FQ
macrolides rifampin linezolid tetracyclines chloramphenicol |
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Tx of sinusitis or otitis media
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S-FQ
OM- CTX IM both: Amoxicillin Augmentin Cephlosporins Zpak |
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When do u tx sinusitis
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>7 days of symptoms
face/tooth pain |
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what do you use to treat common cold and when do u use it
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only symptomatic relief...
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flu tx must be given...
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w/I 48 hours
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abx recommeneded for acute bronchitis
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usually viral so none
if >14 days its pertussis -Zpak -Bactrim -clarithromycin |
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tx for acute bacterial excasterbation chronic bronchitis
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if severe- inhaled anti-Ch bronchdilator
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name of pneumoccal conjugate vaccine and who must it be given too
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Prevnar 13
-childrs 2-23 months don't mix with adults |
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adult pneumococcal vaccine is called
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pneumovax
(has more stereotypes in it) |
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which b-lactams kill pseudomonas
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ceftazidime
cefepime pip/tazo doripenem meropenem imipenem |
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What determines tx of CAP
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severity of dx
outpt vs inpt comorbidities/ abx usage vs not regular bed vs ICU |
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TX of CAP
-outpt outpt complic -inpt uncompl -pseudomonas risk allergy |
Outpt- Macrolide or Doxycycline
Outpt comp/inpt uncomp -FQ or Blactam+macrolide pseudomonas risk -antiP blactam + FQ or AG + azithromycin allergy- add aztreonam |
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CAP tx length
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min 5 days
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HAP tx
<5 days or no reason to think resistant |
CTX
FQ Amp/Sul Ertapenem |
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Late HAP tx
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antipeudomonal Blactam
anti MRSA lung agent (vanco/linezolid) 2nd anti pseudomonal agent |
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TB is
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highly contagious
ha |
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Diag. TB with
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tb skin test
or xray I suppose |
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tx of latent tb
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INH 300mg daily 9 months
or Rifampin 600 mg for 4 months |
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tx active TB
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4 drugs - RIPE
Rifampine, Isoniazid, Pyrazionamide, Ethambutol add FQ if resistant to one |
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what to know about any tb tx
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daily dose recommended
directly observed therapy if possible especially if not on daily regimen |
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what is added to tb reg due to INH
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pyridoxine (AKA Vit B6)
also FYI INH can cause LUPUS LIKE SYNDROME |
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TB SE of Regimen
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flu like syndrome
hepatoxicity orange red fluids take on empty stomach--that doesn't seem like a SE...oh well |
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ethambutol SE
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optic neuritis
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pyrazinamide SE
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hepatotox
hyperuricemia |
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drug interactions
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rifampin- potent inducer
INH- inhibitor |
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dental procedure regimen drug and dose
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amoxicillin 2g
allergic -clindamycin 600mg azithromycin or clarithromycin 500mg |
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IE tx strept viridians
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Mostly PEN G or CTX, AG for synergy
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sTAPH
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naficillin and AG
Vanco if resistant + rifampin for prostetic |
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intraabdominal infections
primary peritonitis DOC |
CTX 5-7 days
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Cholecystitis tx
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usually just remove the gall bladder
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secondary peritonitis DOC severe dx
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carbapenems w/ P activity
or lower end ceph or FQ w/ metro |
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Rickeltsial Dxsss
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Rocky mountain spotty fever
lyme disease typhoid ehrlicheosis tyleremia -tx w/ doxycycline! |
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Non puruelent cellulitis DOC
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B lactam
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Purulent Cellulitis tx
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Lot of options (gram +ve target)
clinda Bactrim doxy mino linezolid 5-10 days |
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complicated SSTI tx
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vanco
linezolid dapto telavancin clinda 7-14 days |
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severe diabetic foot infection
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make sure anti psudomonal on board
7-14 days |
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UTI symptoms
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dysuria
urgency frequency burning nocturia suprapubic heaviness |
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+ve urinalysis when
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pyuria >10 WBC
bacteriuria >16 to the 5 bact / ml |
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UTI tx acute uncomplicated cystitis
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if <20% E coli resistat SMX-TMP
-use it! x 3 days phenaopyridine TID x 2 days to relieve symptoms |
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when proph for UTI
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> or equal 3 episodes a year
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acute uncomplicated pyelonephritis
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FQ or ceph if resistant
severe- FQ, AMP + gent |
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tx all bacteriauria in pregos
and what else |
avoid FQ, tetras and Bactrim(in the 3rd)
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Phenazopyridine notes
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w/ food
no more 2 days (mask symptoms) red range urine discoloration |
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C diff tx w/
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metro
vanco if high recurrence fidoxomicin |
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STIs--they don't even say STDs anymore these frickin tards
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FYI
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Syphilis tx
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Pen G benzathine (LA not CR)
2.4 mill units IM if latent IM x 3 over 3 wks |
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Gonorrhea tx
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CTX 2500mg IM x1
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Chlamydia tx
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Azithromycin 1g PO x1
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Bacterial Vaginosis tx
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metro or metro gel
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Fungals will be in part 2
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fyi
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MIC is
HEY IT WAS UNDERLINED OK |
lowest [] prevent visible growth
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breakpoint is
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when MIC deemed resistant or suseptable
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MBC is
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lower [] that kills botches
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which FQ doesn't get into urine
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Moxi
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which FQ gets lots of other places
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moxi! (ok more like anerobes but whatever)
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how do you max Blactam killing
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extend infusion time
time above MIC |
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which abx are bacteriostatic
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macrolides
clindamycin linezolid tertracylines streptogramins (usually) So if it isn't static its cidal |
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AG, how kills
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[] dependant w/ post abx effect
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ag SE
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BBW for neurotox
nephrotox also ototox |
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PCN, how work and kill type
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inhib wall syn
time dependant killing (x-enterococcus) |
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difference storage for amoxil and augmentin
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Augmentin MUST be refridgerated
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PenVK w/ or w/o food
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w/o food
and in fridge if susp |
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what is ampicillin compaditble with
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NS only
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which blactam is vesicant
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nafcillin
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whats PCN vs ceph crossensitivity for allergies
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<10%
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cefotetan notes
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NMTT side chain....
possible hypoprothrombeniemia and disulfuram like |
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Carbapenems used for
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ESBLs and pseudomonas (not erta)
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FQ BBW
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tendon inflame or rupture
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SE FQ
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photosensitive
glycemic changes (mostly hypo) QT prolong |
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Cipro/levo/Moxi dose
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MOXI has no renal adjust
cipro not lvl IV to PO |
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Azithromycin notes
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do not NOTTTT
refridgerate suspension ZMax |
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Clarithromycin notes
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take biaxin XL w/ food
do not refridge oral susp |
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erythromycin note
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must refridge granule susp and use in 10 days
powder susp is good room temp |
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sulfonamides ratio
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5:1
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Bactrim points
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protect from light
dilute with D5W!!! ccareful w/ warfarin |
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UTI tx w/ bactrom
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1 DS BID 3 days
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PCP proph
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1 DS or ss daily
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daptomycin compatible w/
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NS only
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Vancomycin SE
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nephrotox
ototox red man syndrome hypotension |
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how renal adjust vanco
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extend interval
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when use different agent besides vanco
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MIC > or equal to 2
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Linezolid SE
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MAOI
myelosuspress pancreatic enymzes increase diarrhea |
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synercid SE
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hyperbilirubinemia
phlebitis inflammation at inj site arthralgias myalgias |
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synercid compadible with
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D5W only!!!
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Telavancin (Vibativ)
what class |
lipoglycopeptide derivative
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minocycline names
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minocin
dynacin solody ximino f these guys |
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CA MRSA 1st
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Bactrim
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HA MRSA
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vacno
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VRE facalis
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PenG or amp
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VRE facium
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daptomycin
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ESBLs
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seriously
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acintobacter
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penems (not erta cuz it sucks)
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When airborne precautions nessesary
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rubella virus
variallo virus Mtuberculosis |
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when give surgical abx proph
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hour before
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surg prop what drugs
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cefazolin
cefuroxime vanco if allergic if bowel add metro or cefotetan or ctx |
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what to watch for meningitis
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classic triad
mental fever nuchal rigidity |
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tx acute meningitis
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cefotaxime or CTX or Mero
plus Deamethazone plus vancomycin |
