Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
100 Cards in this Set
- Front
- Back
Gram +ves are generally...
|
Staph
Strep Enterococcus Clostridium Listeria |
|
Gram negatives are generally...
|
not one of the gram positives...
|
|
What are some hydrophilic Abx
|
B lactams
AG Glycopeptides Daptomycin Colistin |
|
What are some lipophilic abx
|
FQ
macrolides rifampin linezolid tetracyclines chloramphenicol |
|
Tx of sinusitis or otitis media
|
S-FQ
OM- CTX IM both: Amoxicillin Augmentin Cephlosporins Zpak |
|
When do u tx sinusitis
|
>7 days of symptoms
face/tooth pain |
|
what do you use to treat common cold and when do u use it
|
only symptomatic relief...
|
|
flu tx must be given...
|
w/I 48 hours
|
|
abx recommeneded for acute bronchitis
|
usually viral so none
if >14 days its pertussis -Zpak -Bactrim -clarithromycin |
|
tx for acute bacterial excasterbation chronic bronchitis
|
if severe- inhaled anti-Ch bronchdilator
|
|
name of pneumoccal conjugate vaccine and who must it be given too
|
Prevnar 13
-childrs 2-23 months don't mix with adults |
|
adult pneumococcal vaccine is called
|
pneumovax
(has more stereotypes in it) |
|
which b-lactams kill pseudomonas
|
ceftazidime
cefepime pip/tazo doripenem meropenem imipenem |
|
What determines tx of CAP
|
severity of dx
outpt vs inpt comorbidities/ abx usage vs not regular bed vs ICU |
|
TX of CAP
-outpt outpt complic -inpt uncompl -pseudomonas risk allergy |
Outpt- Macrolide or Doxycycline
Outpt comp/inpt uncomp -FQ or Blactam+macrolide pseudomonas risk -antiP blactam + FQ or AG + azithromycin allergy- add aztreonam |
|
CAP tx length
|
min 5 days
|
|
HAP tx
<5 days or no reason to think resistant |
CTX
FQ Amp/Sul Ertapenem |
|
Late HAP tx
|
antipeudomonal Blactam
anti MRSA lung agent (vanco/linezolid) 2nd anti pseudomonal agent |
|
TB is
|
highly contagious
ha |
|
Diag. TB with
|
tb skin test
or xray I suppose |
|
tx of latent tb
|
INH 300mg daily 9 months
or Rifampin 600 mg for 4 months |
|
tx active TB
|
4 drugs - RIPE
Rifampine, Isoniazid, Pyrazionamide, Ethambutol add FQ if resistant to one |
|
what to know about any tb tx
|
daily dose recommended
directly observed therapy if possible especially if not on daily regimen |
|
what is added to tb reg due to INH
|
pyridoxine (AKA Vit B6)
also FYI INH can cause LUPUS LIKE SYNDROME |
|
TB SE of Regimen
|
flu like syndrome
hepatoxicity orange red fluids take on empty stomach--that doesn't seem like a SE...oh well |
|
ethambutol SE
|
optic neuritis
|
|
pyrazinamide SE
|
hepatotox
hyperuricemia |
|
drug interactions
|
rifampin- potent inducer
INH- inhibitor |
|
dental procedure regimen drug and dose
|
amoxicillin 2g
allergic -clindamycin 600mg azithromycin or clarithromycin 500mg |
|
IE tx strept viridians
|
Mostly PEN G or CTX, AG for synergy
|
|
sTAPH
|
naficillin and AG
Vanco if resistant + rifampin for prostetic |
|
intraabdominal infections
primary peritonitis DOC |
CTX 5-7 days
|
|
Cholecystitis tx
|
usually just remove the gall bladder
|
|
secondary peritonitis DOC severe dx
|
carbapenems w/ P activity
or lower end ceph or FQ w/ metro |
|
Rickeltsial Dxsss
|
Rocky mountain spotty fever
lyme disease typhoid ehrlicheosis tyleremia -tx w/ doxycycline! |
|
Non puruelent cellulitis DOC
|
B lactam
|
|
Purulent Cellulitis tx
|
Lot of options (gram +ve target)
clinda Bactrim doxy mino linezolid 5-10 days |
|
complicated SSTI tx
|
vanco
linezolid dapto telavancin clinda 7-14 days |
|
severe diabetic foot infection
|
make sure anti psudomonal on board
7-14 days |
|
UTI symptoms
|
dysuria
urgency frequency burning nocturia suprapubic heaviness |
|
+ve urinalysis when
|
pyuria >10 WBC
bacteriuria >16 to the 5 bact / ml |
|
UTI tx acute uncomplicated cystitis
|
if <20% E coli resistat SMX-TMP
-use it! x 3 days phenaopyridine TID x 2 days to relieve symptoms |
|
when proph for UTI
|
> or equal 3 episodes a year
|
|
acute uncomplicated pyelonephritis
|
FQ or ceph if resistant
severe- FQ, AMP + gent |
|
tx all bacteriauria in pregos
and what else |
avoid FQ, tetras and Bactrim(in the 3rd)
|
|
Phenazopyridine notes
|
w/ food
no more 2 days (mask symptoms) red range urine discoloration |
|
C diff tx w/
|
metro
vanco if high recurrence fidoxomicin |
|
STIs--they don't even say STDs anymore these frickin tards
|
FYI
|
|
Syphilis tx
|
Pen G benzathine (LA not CR)
2.4 mill units IM if latent IM x 3 over 3 wks |
|
Gonorrhea tx
|
CTX 2500mg IM x1
|
|
Chlamydia tx
|
Azithromycin 1g PO x1
|
|
Bacterial Vaginosis tx
|
metro or metro gel
|
|
Fungals will be in part 2
|
fyi
|
|
MIC is
HEY IT WAS UNDERLINED OK |
lowest [] prevent visible growth
|
|
breakpoint is
|
when MIC deemed resistant or suseptable
|
|
MBC is
|
lower [] that kills botches
|
|
which FQ doesn't get into urine
|
Moxi
|
|
which FQ gets lots of other places
|
moxi! (ok more like anerobes but whatever)
|
|
how do you max Blactam killing
|
extend infusion time
time above MIC |
|
which abx are bacteriostatic
|
macrolides
clindamycin linezolid tertracylines streptogramins (usually) So if it isn't static its cidal |
|
AG, how kills
|
[] dependant w/ post abx effect
|
|
ag SE
|
BBW for neurotox
nephrotox also ototox |
|
PCN, how work and kill type
|
inhib wall syn
time dependant killing (x-enterococcus) |
|
difference storage for amoxil and augmentin
|
Augmentin MUST be refridgerated
|
|
PenVK w/ or w/o food
|
w/o food
and in fridge if susp |
|
what is ampicillin compaditble with
|
NS only
|
|
which blactam is vesicant
|
nafcillin
|
|
whats PCN vs ceph crossensitivity for allergies
|
<10%
|
|
cefotetan notes
|
NMTT side chain....
possible hypoprothrombeniemia and disulfuram like |
|
Carbapenems used for
|
ESBLs and pseudomonas (not erta)
|
|
FQ BBW
|
tendon inflame or rupture
|
|
SE FQ
|
photosensitive
glycemic changes (mostly hypo) QT prolong |
|
Cipro/levo/Moxi dose
|
MOXI has no renal adjust
cipro not lvl IV to PO |
|
Azithromycin notes
|
do not NOTTTT
refridgerate suspension ZMax |
|
Clarithromycin notes
|
take biaxin XL w/ food
do not refridge oral susp |
|
erythromycin note
|
must refridge granule susp and use in 10 days
powder susp is good room temp |
|
sulfonamides ratio
|
5:1
|
|
Bactrim points
|
protect from light
dilute with D5W!!! ccareful w/ warfarin |
|
UTI tx w/ bactrom
|
1 DS BID 3 days
|
|
PCP proph
|
1 DS or ss daily
|
|
daptomycin compatible w/
|
NS only
|
|
Vancomycin SE
|
nephrotox
ototox red man syndrome hypotension |
|
how renal adjust vanco
|
extend interval
|
|
when use different agent besides vanco
|
MIC > or equal to 2
|
|
Linezolid SE
|
MAOI
myelosuspress pancreatic enymzes increase diarrhea |
|
synercid SE
|
hyperbilirubinemia
phlebitis inflammation at inj site arthralgias myalgias |
|
synercid compadible with
|
D5W only!!!
|
|
Telavancin (Vibativ)
what class |
lipoglycopeptide derivative
|
|
minocycline names
|
minocin
dynacin solody ximino f these guys |
|
CA MRSA 1st
|
Bactrim
|
|
HA MRSA
|
vacno
|
|
VRE facalis
|
PenG or amp
|
|
VRE facium
|
daptomycin
|
|
ESBLs
|
seriously
|
|
acintobacter
|
penems (not erta cuz it sucks)
|
|
When airborne precautions nessesary
|
rubella virus
variallo virus Mtuberculosis |
|
when give surgical abx proph
|
hour before
|
|
surg prop what drugs
|
cefazolin
cefuroxime vanco if allergic if bowel add metro or cefotetan or ctx |
|
what to watch for meningitis
|
classic triad
mental fever nuchal rigidity |
|
tx acute meningitis
|
cefotaxime or CTX or Mero
plus Deamethazone plus vancomycin |