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23 Cards in this Set
- Front
- Back
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Describe treatment guidelines by acne vulgaris type
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I - Benzoyl peroxide
II - Topic antibiotics and topical retinoids III - Topical therapy (benzoyl peroxide, retinoids, antibotics) + oral antibiotics IV - Can be treated with topical + oral therapy, but most often requires oral isotretinoin |
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What must all females of child bearing age taking oral isotretinoin therapy agree to?
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To use two forms of contraception during use - very teratogenic
***All patients, pharmacies, physicians, and wholesalers must register with the iPLEDGE program - FDA program designed to monitor and ecrease the risk of fetal exposure to isotretinoin*** |
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Name the three non-prescription acne agents
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Benzoyl peroxide
Sulfur Salicylic acid ***Excessive drying, photosensitivity, peeling, erythema*** |
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Name the topical antimicrobials (gel, lotion)
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Clindamycin (Cleocin)
Erythromycin (Theramycin) ***Burning, dryness, itching, irritation*** |
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Name the topical retinoids (gel, cream, lotion)
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Tretinoin (Retin-A)
Adapalene (Differin) Tazarotene (Tazorac) Alitretinoin (Panretin) ***Photosensitivity, burning, dryness, erythema, irritation*** |
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Name the 4 oral antibiotics
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Tetracycline (Achromycin)
Doxycyline (Vibramycin) Minocycline (Minocin) Erythromycin (Erythrocin) |
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Primary side effects of Tetracycline antibiotics
Medication pearl |
Rash
Photosensitivity GI upset Take 2 hours before or after meals and avoid calcium containing foods |
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Primary side effects of Erythromycin
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GI upset
Diarrhea Nausea/Vomiting Abdominal pain ***Significant drug interactions and GI side effects limit use*** |
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Isotretinoin (Accutane) primary side effects
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Cheilitis (inflammation of the lip)
Dry mouth, skin GI upset Headaches Hyperlipidemia (requires period lipid panel) Depression (rare) Contraindicated in pregnancy |
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Distinguish between the two types of psoriasis
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Type I - presents early in life in those with a family history
Type II - presents later in life, usually with no family history Both are a chronic inflammatory condition of the skin presenting with silvery scalelike lesions |
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What is psoriatic arthritis?
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Arthritis and joint pain secondary to psoriasis
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There is significant inter-patient variability in response to the available medications. What are you're options for initial treatment?
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Topical agents: Emollients, keratolytics (salicylic acid or sulfur), coal tar, antralin, calcipotriene, or retinoids
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Systemic options are used in severe cases. What systemic options do you have?
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Antimetabolite therapy (methotrexate, cyclosporine, tacrolimus), oral corticosteroids, psoralens, immunosuppressants, or retinoids
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Name the topical retinoids
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Tretinoin (Retin-A)
Adapalene (Differin) Tazarotene (Tazorac) Alitretinoin (Panretin |
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Name the only anthralin agent
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Dithranol
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Name Dithranol's primary side effects
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Discoloration of skin, hair, fabrics, irritation
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Calcipotriene (Dovonex) is contraindicated in
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Hypercalcemia
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What is the vitamin D analog?
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Calcitriol (Vectical)
***Topical product inlikely to cause drug interactions or serum abnormalities due to limited systemic absorption*** |
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Methotrexate is given once weekly. What is its primary side effects?
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Leukopenia
Hepatotoxicity Photosensitivity Nausea, Fatigue, Chills, Fever |
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What do you want to monitor in a patient taking methotrexate?
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CBC
Liver enzymes ***Pregnancy category X - must use contraception*** |
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Name the 4 immunosuppressants used in psoriasis
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Alefacept (Amevive)
Etanercept (Enbrel) Efalizumab (Raptiva) Ustekinumab (Stelara) |
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Which one of these agents is contraindicated if your CD4 count is less than 250 or you have HIV? Differentiate between these agents in terms of side effects
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Alefacept (Causes lymphopenia)
Etanercept causes neutropenia Efalizumab causes thrombocytopenia They all increase your risk of infection and should require a PPD before therapy initiation -Also do not give live vaccines |
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Name the oral (systemic) retinoid that can be used
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Acitretin (Soriatane)
***Law requires a medication guide to be given each time this is dispensed - pregnancy category X*** |
