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17 Cards in this Set

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how to take levothyroxine?

- 60 mins before breakfast


- or at bedtime (at least 3 hours after last meal)

what are available dose tablets for levothyroxine?

25, 50, 75, 88, 100, 112, 125, 137, 150, 175, 200, 300

what are the colors for levothyroxine?

Orangutans will vomit on you right before they become larger, proud giants


(orange, white, violet, olive, yellow, rose, brown, turquoise, blue, lilac, pink, green)


25, 50, 75, 88, 100, 112, 125, 137, 150, 175, 200, 300

most common cause for hypothyroidism?

Hashimoto's disease

most common cause for hyperthyroidism?

Grave's disease

drugs cause hypothyroidism?

- aluminum (antacids), calcium, mutivit,....


- estrogen, SSRIs


- beta blockers, amiodarone, sys steroids


- highly protein bound (99%), (heparin, phenytoin, NSAID)

drugs cause hyperthyroidism?

- iodines, amiodarone and interferons

what is treatment of choice for Grave's disease?

- RAI-131 (radio active iodine)

for hypothyroidism, if patient has CAD, what is the dose for levothyroxine?

start with 12.5 - 25 mcg daily

what is the iv to po ratio for levothyroxine?

iv to po ratio is 0.75 to 1

What are two drugs to treat hyperthyroid? (antithyroid)

- PTU (propylthiouracil) (prefer in thyroid storm)- use in 1st trimester


- Methimazole (Tapazole) - use in 2nd and 3rd trimester


- ADR: GI upset, hepatitis, agranulocytosis (low WBC, rare)


- can decrease the anticoagulant effect of warfarin

treatment for Thyroid Storm?

- PTU + SSKI + propranolol + dexamethasone + acetaminophen + cooling blanket

what is the full replacement starting dose of Synthroid?

88 mcg QD

generic for Cytomel ?

liothyronine (T3)

generic for Tapazole?

Methimazole

full replacement dose of levothyroxine by calculation?

1.6 mcg/kg/day for <50 yo


0.5 mcg/kg/day for elderly

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