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28 Cards in this Set

  • Front
  • Back
Which statement is correct about DIC?

a. It was once known as hemophilia A.

b. It’s both a bleeding and thrombotic disorder.

c. It’s a clinically insignificant syndrome.

d. It’s never a complication of another condition.
b. It’s both a bleeding and thrombotic disorder.
Proinflammatory cytokines released in DIC include

a. neutrophils
b. eosinophils
c. macrophages
d. tumor necrosis factor alpha
d. tumor necrosis factor alpha

*the other is interleukins
What is the action of proinflammatory cytokines?
Activate the clotting cascade and cause microclots to form within the capillaries
Fibrin degradation products are potent

a. anticoagulants
b. clotting factors
c. antilytic agents
d. procoagulants
a. anticoagulants
Which is associated with a chronic form of DIC?

a. arterial hypotension
b. cancer
c. hypoxemia
d. acidemia
b. cancer

*along with liver dysfunction, the other clinical conditions increase the risk of DIC
The first and most obvious sign of DIC often is

a. abdominal distension
b. bleeding
c. peripheral edema
d. abnormal breath sounds
b. bleeding
A less obvious sign of DIC is

a. thrombosis
b. polyuria
c. polydipsia
d. polyphagia
a. thrombosis
Thrombosis in DIC is most likely to affect

a. the common iliac artery
b. the subclavian artery
c. the descending aorta
d. cutaneous capillaries
d. cutaneous capillaries
Which lab finding is a strong indicator of DIC?

a. an elevated platelet count
b. an elevated D-dimer test
c. a normal prothrombin time
d. an elevated fibrinogen level
b. an elevated D-dimer test

**this indicates excessive fibrinolysis
What does an elevated D-dimer test indicate?
Excessive fibrinolysis, which is a strong indicator of DIC
Which contributes to DIC by diluting clotting factors and naturally occurring antithrombins?

a. multiple blood transfusions
b. hypotension
c. hypoxemia
d. acidosis
a. multiple blood transfusions
Cryoprecipitate is administered to

a. correct low platelet counts
b. replace severely depleted fibrinogen levels
c. restore oxygen-carrying capacity
d. replace acute massive blood losses
b. replace severely depleted fibrinogen levels
Packed red blood cells is administered to

a. correct low platelet counts
b. replace severely depleted fibrinogen levels
c. restore oxygen-carrying capacity
d. replace acute massive blood losses
c. restore oxygen-carrying capacity
Fresh frozen plasma is administered to

a. correct low platelet counts
b. replace severely depleted fibrinogen levels
c. restore oxygen-carrying capacity
d. replace depleted clotting factors
d. replace depleted clotting factors
Platelet transfusions is administered to

a. correct low platelet counts
b. replace severely depleted fibrinogen levels
c. restore oxygen-carrying capacity
d. replace acute massive blood losses
a. correct low platelet counts

(correct low platelet counts are due to thrombocytopenia from ongoing bleeding)
Which blood product is given to correct thrombocytopenia from ongoing bleeding?

a. PRBCs
b. fresh frozen plasma
c. platelet concentrate
d. whole blood
c. platelet concentrate
Which statement best describes heparin therapy in DIC?

a. It dissolves existing clots.
b. It’s absolutely contraindicated in DIC.
c. It’s a fibrinolytic agent.
d. It can help block new microclot formation.
d. It can help block new microclot formation.
Which drug can restore the normal physiologic anticoagulant pathway in DIC?

a. unfractionated heparin
b. epsilon-aminocaproic acid
c. recombinant human activated protein C
d. low-molecular-weight heparin
c. recombinant human activated protein C
To guide treatment in DIC, obtain repeat coagulation studies every

a. 4 hours
b. 8 hours
c. 24 hours
d. 72 hours
a. 4 hours
Which nursing intervention is most appropriate for a patient with DIC?

a. Regularly examine his skin for painful hematomas and ischemic changes
b. Use an automatic BP cuff
c. Draw blood specimens by direct venipuncture
d. Use high-level tracheal or oral suctioning
a. Regularly examine his skin for painful hematomas and ischemic changes
Fragmented red blood cells that were damaged while circulating through obstructed blood vessels are called

a. elliptocytes
b. spherocytes
c. stomatocytes
d. schistocytes
d. schistocytes
A normal D-dimer test result is

a. 12 seconds
b. less than 200 ng/ml
c. 150-400 mg/dl
d. 150,000-400,000/mm3
b. less than 200 ng/ml
Which lab result might you find in a patient with DIC?

a. antithrombin III of less than 80%
b. Factor V assay greater than 150%
c. fibrin degradation products less than 10 mcg/ml
d. fibrinogen greater than 150 mg/dl
a. antithrombin III of less than 80%

**the other lab results are normal
Secondary fibrinolysis in DIC leads to

a. systemic activation of coagulation
b. fibrin deposits in the microcirculation
c. ischemic tissue damage
d. diffuse bleeding
d. diffuse bleeding
A normal prothrombin time or international normalized ratio (INR) test result is

a. 12 seconds
b. less than 200 ng/ml
c. 150-400 mg/dl
d. 150,000-400,000/mm3
a. 12 seconds (INR, 1.0)
A normal platelet count test result is

a. 12 seconds
b. less than 200 ng/ml
c. 150-400 mg/dl
d. 150,000-400,000/mm3
d. 150,000-400,000/mm3
A normal fibrinogen test result is

a. 12 seconds
b. less than 200 ng/ml
c. 150-400 mg/dl
d. 150,000-400,000/mm3
c. 150-400 mg/dl
What factors increases the risk of DIC?
1. Arterial hypotension
2. Acidemia
3. Liver dysfunction
4. Hypoxemia