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81 Cards in this Set

  • Front
  • Back
What is extremely low-birth-weight infants?
Infants whose birth weigh is 1000 grams or less
What problems may affect the respiratory systems of preterm infants?
1. Decreased number of functional alveoli
2. Deficient surfactant levels
3. Greater collapsibility or obstruction of respiratory passages
4. Insufficient calcification of the bony thorax
5. Weak or absent gag reflex
6. Immature and friable capillaries in the lungs
7. Greater distance between functional alveoli and the capillary bed
What is the normal respiratory rate of infants?
30 to 60 breaths/min
What are the early signs of respiratory distress?
Flaring of the nares and expiratory grunting
What indicates worsening respiratory distress?
Seesaw breathing patterns, retractions, flaring of the nares, expiratory grunting, and/or apneic spells
What is normal periodic breathing?
5- to 10-second respiratory pauses followed by 10 to 15 seconds of compensatory rapid respirations
What is apnea?
15- to 20-second cessation of respirations
What are symptoms of hypovolemia or shock?
Hypotension, slow capillary refill (>3 seconds), and continued respiratory distress despite provision of oxygen and ventilation
What factors place preterm infants at risk for temperature instability?
1. Large body surface area in relation to weight
2. Minimal insulating subQ fat
3. Limited stores of brown fat
4. Fragile capillaries
5. Decreased or absent reflex control of skin capillaries (shiver response)
6. Inadequate muscle mass activity (rendering the preterm infant unable to produce its own heat)
7. Poor muscle tone resulting in more body surface area being exposed to the cooling effects of the environment
8. An immature temperature regulation center in the brain
What are the signs of cold stress?
1. Skin temperature decreases before other signs
2. RR increases initially, then apneic spells occur
3. HR increases initially, then bradycardia occurs
4. Mottled skin color with acrocyanosis increasing to cyanosis
5. Increased physical activity in term infants without respiratory distress -or- Decreased physical activity in term infants with respiratory distress -or- Decreased physical activity in preterm infants
6. Unstable thermoregulatory control in premature infants
What problems cause the preterm infant's CNS to be susceptible to injury?
1. Birth trauma that includes damage to immature structures
2. Bleeding from fragile capillaries
3. An impaired coagulation process, including prolonged prothrombin time
4. Recurrent anoxic episodes
5. Predisposition to hypoglycemia
What disadvantages do preterm infants have regarding intake?
1. Weak or absent suck, swallow, gag reflexes
2. A small stomach capacity
3. Weak abdominal muscles
4. Compromised metabolic functions ==> limited store of nutrients, decreased ability to digest proteins or absorb nutrients, and immature enzyme systems
What is the preterm infant's immature renal system unable to do?
1. Adequately excrete metabolites and drugs
2. Concentrate urine
3. Maintain acid-base, fluid, or electrolyte balance
What hematologic problems are preterm infants predisposed to?
1. Increased capillary fragility
2. Increased tendency to bleed (prolonged PTT and partial thromboplastin time)
3. Slowed production of RBCs resulting from rapid decrease in erythropoiesis after birth
4. Loss of blood due to frequent blood sampling for lab tests
5. Decreased RBC survival r/t the relatively larger size of the RBC and its increased permeability to sodium and potassium
What are signs of anemia to look for in infants?
1. Decreased hemoglobin and hematocrit levels
2. Pale skin
3. Increased apnea
4. Lethargy
5. Tachycardia
6. Poor weight gain
Why are preterm infants at increased risk for infection?
1. They have a shortage of stored maternal immunoglobulins
2. They have an impaired ability to make antibodies
3. They have a compromised integumentary system
What is the single most important measure to prevent iatrogenic infections?
Handwashing
What is important to remember regarding growth and development of preterm infants?
The growth and developmental milestones are corrected for gestational age until the child is approximately 2.5 years old
What characteristics should the infant exhibit at discharge from the hospital?
1. Ability to raise head when prone and hold the head parallel with the body when tested for head-lag response

2. An ability to cry with vigor when hungry

3. An appropriate amount and pattern of weight gain according to a growth grid

4. Neurologic responses appropriate for corrected age
What environmental support measures are provided for preterm infants in NICU or ICU?
1. An incubator or radiant warmer placed over the infant to control body temperature
2. Oxygen administration, depending on the infant's cardiopulmonary and circulatory status
3. Electronic monitors as needed for the observation of respiratory and cardiac functions
4. Assistive devices for positioning the infant in neutral flexion and with boundaries
5. Clustering of care and minimization of stimulation according to infant cues
What are various metabolic measures provided in NICU and ICU?
1. Parenteral fluids to help support nutrition and maintain normal arterial blood gas (ABG) levels and acid-base balance

2. IV access to facilitate the administration of antibiotic therapy if sepsis is a concern

3. Blood work to monitor ABG levels, pH, blood glucose levels, electrolytes, and the status of blood cultures
What are the clinical criteria for identifying the need for oxygen?
1. Increased respiratory effort
2. Respiratory distress with apnea
3. Tachycardia
4. Bradycardia
5. Central cyanosis with or without hypotonia
What is the goal of weaning?
The withdrawal of all oxygen support. However, some infants do not achieve this before discharge from hospital and may require home oxygen therapy for several months
What is assessed during the weaning process?
Signs and symptoms indicating poor tolerance of the process, such as increased pulse, respiratory distress, or cyanosis, or a combination of these
What are the signs and symptoms indicating poor tolerance of the weaning process?
Increased pulse, respiratory distress, or cyanosis, or a combination of these
What are the benefits of nonnutritive sucking?
1. Improve oxygenation
2. May lead to decreased energy expenditure with less restless
3. Positive weight gain
4. Promote faster attachment to nipple when oral feedings are initiated
How soon can the suck-and-swallow reflex be coordinated?
As early as 32 weeks of gestation
Why should harsh lights not be used with preterm infants?
The retina of the immature infant has little protection from the nearly translucent eyelid
What are some stress cues of infants?
1. Increased metabolic rate
2. Increased oxygen and caloric use
3. Depression of the immune system
What body position is preferred for preterm infants in the nursery?
Side-lying or prone (compared to supine)
What encourages flexion of the extremities for the preterm infant?
1. Prone position
2. A sling or hip roll
What are the infant's clues to overstimulation?
1. Averting the gaze
2. Hiccuping
3. Gagging
4. Regurgitating food
What is indicative of a relaxed infant?
1. Stabilization of vital signs
2. Closed eyes
3. Relaxed posture
What is kangaroo care?
Skin-to-skin holding
What are the reported benefits of kangaroo care?
1. Increased breast milk output
2. Fewer feelings of helplessness r/t the experiences in the NICU
3. Infants maintain their temperatures and oxygenation levels better
4. Infants experience fewer episodes of crying, apnea, and periodic respirations
What is respiratory distress syndrome (RDS)?
A lung disorder usually affecting preterm infants
What causes RDS?
1. Lack of pulmonary surfactant
2. Progressive atelectasis
3. Loss of functional residual capacity
4. A ventilation/perfusion imbalance with an uneven distribution of ventilation
What causes surfactant deficiency?
1. Insufficient surfactant production
2. Abnormal composition and function
3. Disruption of surfactant production
4. Weak respiratory muscles and an overly compliant chest wall
5. Combination of the above factors
What causes further compromised lung capacity?
The presence of proteinaceous material and epithelial debris in the airways. The resulting decreased oxygenation, cyanosis, and metabolic and respiratory acidosis can cause the pulmonary vascular resistance (PVR) to be increased. This increased PVR can lead to right-to-left shunting and a reopening of the ductus arteriosus and foramen ovale.
What can an increased PVR lead to?
A right-to-left shunting and a reopening of the ductus arteriosus and foramen ovale
What are the clinical signs of RDS?
1. Tachypnea
2. Grunting
3. Flaring
4. Retractions
5. Cyanosis
6. Increased work of breathing
7. Hypercapnia
8. Respiratory or mixed acidosis
9. Hypotension and shock
What is the treatment of RDS?
Supportive - adequate ventilation and oxygenation must be established and maintained in an attempt to prevent ventilation/perfusion mismatch and atelectasis. Exogenous surfactant may be administered.
What complications are associated with mechanical ventilation?
1. Pulmonary interstitial emphysema
2. Pneumothorax
3. Pneumomediastinum
4. Pneumopericardium
How is acid-base evaluated in the preterm infant?
By monitoring the ABG values
What does frequent blood sampling require?
Arterial access either by umbilical artery catheterization or by a peripheral arterial line
How are trends in ventilation and oxygenation documented?
With pulse oximetry and transcutaneous carbon dioxide and oxygen monitors
What is evaluated to rule out neonatal pneumonia?
1. Sepsis evaluation
2. CBC with differential
3. Lumbar puncture
What is administered while the results of cultures are pending when trying to rule out neonatal pneumonia?
Broad-spectrum antibiotics
What is the function of capillary blood gas values?
Indicate the pH and P-CO2 status in infants who are in more stable condition
What helps evaluate the infant's hydration status?
Daily monitoring of the electrolyte values, urinary output, specific gravity, and weight
What are the normal arterial blood gas values for neonates?
1. pH = 7.32 - 7.49

2. Arterial O2 pressure = 60-70 mmHg

3. CO2 pressure = 26-41 mmHg

4. Bicarbonate (HCO3) = 16-24 mEq/L

5. O2 Sat = 40% - 90%
What assessment tools have been developed to assess pain in neonates?
1. CRIES
2. Pain Assessment Tool (PAT)
3. Scale for Use in Newborns (SUN)
4. Behavioral Pain Score (BPS)
etc.
Do neonates remember pain?
Reports have indicated that infants remember painful events and that continual exposure to pain affects development, especially in response to human contact
What are some manifestations of acute pain in the neonate?
1. Increased HR
2. Increased BP
3. Rapid, shallow respirations
4. Decreased O2 sat
5. Crying, whimpering, groaning
6. Grimaces, brow furrowed, chin quivering, eyes tightly shut, mouth open and squarish
7.Limb withdrawal, thrashing, rigidity, flaccidity, fists clenched
What are some nonpharmacological measures to alleviate pain?
1. Repositioning
2. Swaddling
3. Containment
4. Cuddling
5. Rocking
6. Music
7. Reducing environmental stimulation
8. Tactile comfort measures
9. Nonnutritive sucking
10. Use of oral sucrose
What is the most common pharmacological measure to alleviate pain?
Morphine (with fentanyl as an effective alternative)
What are near-term infants?
Infants born between 34 and 37 weeks of gestation
What complications arise with near-term infants?
They experience temperature instability; hypoglycemia and poor feeding necessitating IV therapy; jaundice; evaluation for sepsis 3x more often than term infants, and need treatment with antibiotics
What is a postmature infant?
One that is born after 42 weeks of gestation
What complications occur with postmaturity?
Placental insufficiency, resulting in a fetus that has a wasted appearance (dysmaturity) at birth because of loss of subQ fat and muscle mass
What is dysmaturity?
Wrinkly, pruny appearance
What are postmature infants at risk for?
Meconium Aspiration Syndrome (MAS) because there is insufficient gas exchange in the postmature placenta, which can lead to hypoxia
What methods can be used to prevent Meconium Aspiration Syndrome (MAS)?
1. Amnioinfusion to thin out the meconium particles

2. Use of surfactant lavage immediately after birth

3. Suctioning of the hypopharynx after birth of the head and before birth of the shoulders
What is persistent pulmonary hypertension of the newborn (PPHN)?
Combined findings of pulmonary hypertension, right-to-left shunting, and a structurally normal heart
What is characteristic of PPHN?
It usually proceeds into a downward spiral of exacerbating hypoxia and pulmonary vascoconstriction
What do infants born with PPHN present with at birth?
Tachycardia and cyanosis
What are the physical characteristics of postmature infants?
1. Normal skull, but the reduced dimensions of the rest of the body make the head look disproportionately large

2. Dry, cracked, parchment-like skin at birth

3. Hard nails extending beyond the fingers

4. Profuse scalp hair

5. Depleted subQ fat layers, leaving the skin loose ("old and wrinkly")

6. Long and thin body

7. Absent vernix

8. Often presence of meconium staining or perinatal infection

9. May have alert, wide-eyed appearance symptomatic of intrauterine hypoxia
What problems commonly affect SGA and IUGR infants?
1. Perinatal asphyxia
2. Meconium aspiration
3. Hypoglycemia
4. Polycythemia
5. Heat loss
What are the symptoms of hypoglycemia?
1. Poor feeding
2. Hypothermia
3. Diaphoresis
4. Tremors and jitterness
5. Weak cry
6. Lethargy
7. Floppy posture
8. Convulsions or coma
What is polycythemia?
Hyperviscosity of the blood (thick blood)
What causes polycythemia?
Fetal hypoxia and intrauterine stress that forces the body to produce more RBCs in an attempt to provide oxygen to the developing fetus
What increases the susceptibility of SGA infants to heat loss?
1. Less muscle mass
2. Less brown fat
3. Less heat-preserving subQ fat
4. Little ability to control skin capillaries
What complications may be experienced by LGA infants?
1. Transposition of the great vessel
2. Beckwith-Wiedemann syndrome
3. Birth trauma
4. Asphyxia or CNS injury, or both
5. Polycythemia???
What is apnea?
Cessation of respirations for MORE than 15 seconds associated with cyanosis
What is bronchopulmonary dysplasia (BPD)?
Pulmonary condition affecting preterm infants who have experienced respiratory failure and have been O2 dependent for more than 28 days
What is dysmaturity?
Fetal undergrowth of any cause


Also known as INTRAUTERINE GROWTH RESTRICTION (IUGR)
What is Transient Tachypnea of Newborn (TTN)?
1. Rapid and labored breathing in newborns that usually goes away after a few days (with treatment)

2. If not treated, insufficient O2 to the lungs will cause insufficient production of surfactant and can lead to respiratory distress
What is the best formula choice, and why -- 13, 20, or 24 calorie based formula?
20 because it is most similar in calories to breast milk
Like the preterm infant, the newborn with postmaturity is at high risk for cold stress due to what?
Decreased subcutaneous tissue
What is an early sign of sepsis is in newborns?
Tachycardia
What is the MAJOR concern for newborns with a high concentration of indirect bilirubin?
Neurotoxicity