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55 Cards in this Set

  • Front
  • Back
Common side effects of chemotherapy and radiation
Bone marrow suppression (what labs should we pay attention to???????????????)
Fatigue and muscle weakness (think about nursing implications!!!!!!!!!!!)
GI disturbances (Nutrition implications!!!!!!!!!)
Nausea, vomiting, diarrhea, constipation
Integumentary and mucosal reactions (Nutrition and body image!!!!!!!!!)
Stomatitis, hair loss
Pulmonary effects
Pulmonary fibrosis & pneumonitis
Reproductive effects
Cardiac effects
Arrhythmias, CHF, Cardiac toxicity
Hgb
used to determine the severity of anemia
mild anemia

moderate anemia

severe anemia
10-14g/dl

6-10g/dl

<6 g/dl
mild anemia sxs
May exist without symptoms
Possible symptoms
Palpitations, exertional dyspnea, diaphoresis
Moderate anemia
Increased cardiopulmonary symptoms
Dyspnea experienced at rest or during activity
Fatigue
severe anemia
Integument
Pallor
↓ Hemoglobin
↓ Blood flow to the skin
Jaundice
Hemolysis of of RBCs
↑ Concentration of serum bilirubin
Pruritus
↑ Serum and skin bile salt concentrations
severe
Severe = Hb <6 g/dl
Pulmonary
Tachypnea
Orthophea
Dyspnea at rest
Neurologic
Headache
Vertigo
Irritability
Depression
Gastrointestinal (GI)
Anorexia
Sore mouth
Musculoskeletal
Bone pain
General
Lethargy
Fatigue
Sensitivity to hot and cold
Iron-Deficiency Anemia Clinical Manifestations
Pallor is the most common finding
Ear lobes, palms, and conjuctiva
Glossitis is the second most common
Inflammation of the tongue
Pica
Dizziness
Fatigue shortness of breath
Cobalamin Deficiency Clinical Manifestations
Sore tongue
Anorexia
Nausea
Vomiting
Abdominal pain
Neuromuscular manifestations
Weakness
Paresthesias of the feet and hands
↓ Vibratory and position senses
Ataxia (gross lack of coordination of muscle movement)
Muscle weakness
Impaired thought process
Sickle Cell Disease Clinical Manifestations
Typical patient is asymptomatic except during sickling episodes
Symptoms can be (see fig 31-4 next page)
Pain and joint swelling
Pallor of mucous membranes
Fatigue
Jaundice
Irritability
Hemophilia Clinical Manifestations
Prolonged bleeding from small cuts or injuries
Delay of onset of bleeding after injury
subQ hematomas
GI bleeding
Hematuria
Pain due to compression of hematomas
Hemarthrosis (joint bleeding and swelling
DIC Clinical Manifestations
Nervous system
Vission changes
Dizziness
Headache
Irritability
Anxiety
Confusion
seizures
Integumentary
↓ skin temp
Pallor
Gums bleeding
Hematomas
GI
Abdominal pain
Abdominal dissention
Blood in stool
Respiratory
Dyspnea
Tachypnea
Orthopnea
Decreased breath sounds
Chest pain
Cardiovascular
Decreased pulses
Decreased capillary refill time
Tachycardia
Venous dissention
Genitouinary
Hematuria
oliguria
Musculoskeletal
Joint pain
Bone pain
weakness
Types of Angina:Chronic Stable Angina
Intermittent chest pain that occurs over a long period with the same pattern of onset, duration, and intensity of symptoms
Pain usually lasts 3 to 5 minutes
Subsides when the precipitating factor is relieved
Pain at rest is unusual
ECG reveals ST segment depression
Types of Angina:Prinzmetal’s Angina
Occurs at rest usually in response to spasm of major coronary artery
Seen in patients with a history of migraine headaches and Raynaud’s phenomenon
Spasm may occur in the absence of CAD
When spasm occurs
Chest pain
Marked, transient ST segment elevation
May occur during REM sleep
May be relieved by moderate exercise
Types of Angina Chronic Stable Angina
Intermittent chest pain that occurs over a long period with the same pattern of onset, duration, and intensity of symptoms
Pain usually lasts 3 to 5 minutes
Subsides when the precipitating factor is relieved
Pain at rest is unusual
ECG reveals ST segment depression
Clinical Manifestations of ACS Unstable Angina
Unstable angina
New in onset
Occurs at rest
Has a worsening pattern
UA is unpredictable and represents a medical emergency
Clinical Manifestations of ACS Myocardial Infarction (MI) #1
Result of sustained ischemia (>20 minutes), causing irreversible myocardial cell death (necrosis)
Necrosis of entire thickness of myocardium takes 4 to 6 hours
The degree of altered function depends on the area of the heart involved and the size of the infarct
Contractile function of the heart is disrupted in areas of myocardial necrosis
Most MIs involve the left ventricle (LV)
Clinical Manifestations of ACS MI #2
Fear and anxiety
Dyspnea
Sympathetic nervous system stimulation results in
Release of glycogen
Diaphoresis
Vasoconstriction of peripheral blood vessels
Skin: ashen, clammy, and/or cool to touch
Clinical Manifestations of ACS MI #3
Pain
Total occlusion → anaerobic metabolism and lactic acid accumulation → severe, immobilizing chest pain not relieved by rest, position change, or nitrate administration
Described as heaviness, constriction, tightness, burning, pressure, or crushing
Common locations: substernal, retrosternal, or epigastric areas; pain may radiate
Clinical Manifestations of ACS MI #4
Cardiovascular
Initially, ↑ HR and BP, then ↓ BP (secondary to ↓ in CO)
Crackles
Jugular venous distention
Abnormal heart sounds
S3 or S 4
New murmur
Nausea and vomiting
Can result from reflex stimulation of the vomiting center by the severe pain
Fever
Systemic manifestation of the inflammatory process caused by cell death
Sudden Cardiac Death : risk factors
Primary risk factors
Left ventricular dysfunction (EF 30%)
Ventricular dysrhythmias following MI
Other risk factors
Male gender (especially African American men)
Family history of premature atherosclerosis
Tobacco use
Diabetes mellitus
Hypercholesterolemia
Hypertension
Cardiomyopathy
Hypertension Clinical Manifestations
Fatigue, reduced activity tolerance
Dizziness
Palpitations, angina
Headaches
Weight gain
Edema
Muscle cramps
Blurred vision
Nocturia
Dyspnea
Hypertensive Crisis: s&sxs
Severe, abrupt increase in DBP (defined as >140 mm Hg)
Rate of increase in BP is more important than the absolute value (think trends)
Often occurs in patients with a history of HTN who have failed to comply with medications or who have been undermedicated
Heart Failure Presenting signs

LEFT
Alternating pulse strength
Tachycardia
Decrease in SaO2 & PaO2
Crackles
S3 and S4 heart sounds (gallop rhythm)
Restlessness and confusion
Cyanosis
Tachypnea
Pleural effusion (fluid between lung and chest wall)
Heart Failure Presenting signs

RIGHT
Murmurs
JVD (jugular venous distention) above clavicle when in sitting at 45 degree angle
Edema
Weight gain (Sudden weight gain of >3 lb (1.4 kg) in 2 days may indicate an exacerbation of HF)
Tachycardia
Hepatomegaly
Heart Failure Presenting symptoms RIGHT
Weakness and Fatigue
Anxiety an depression
Dependent bilateral edema
Right upper quadrant discomfort
Nausea
GI bloating
Heart Failure Presenting symptoms: LEFT
Weakness fatigue
Anxiety and depression
Dyspnea on exertion
Orthopnea (number of pillows)
Paroxymal nocturnal dyspnea (nightime attacks of breathlessness)
Nocturia
Dry hacking cough
Peripheral Arterial Disease Manifestations
PAD—intermittent claudication
Ischemic muscle ache or pain that is precipitated by a constant level of exercise
Resolves within 10 minutes or less with rest
Reproducible
Shooting or burning pain in extremity
Present near ulcerated areas
Produces loss of pressure and deep pain sensations
Injuries often go unnoticed by patient
Peripheral Arterial Disease Manifestations
#2
Thin, cool, shiny, and taut skin
Loss of hair on the lower legs
Diminished or absent pedal, popliteal, or femoral pulses
Pallor
Reactive hyperemia (increased blood flow after ischemia)
Pain at rest
Occurs in the forefoot or toes and is aggravated by limb elevation
Occurs from insufficient blood flow
Occurs more often at night
Aortic Aneurysm Manifestations:
THORACIC
Often asymptomatic with first sign being rupture
Main have pain in back, neck, substernal area when lying supine
May have dyphagia and dyspnea, stridor or cough when pressing on esophagus or largngeal nerve
Aortic Aneurysm Manifestations:
ABDOMINAL
“heartbeat” in abdomen when lying down
Pulsating abdominal mass
Abdominal or lumbar pain
Claudication
Cool or cyanotic extremities
Systolic bruit may be heard
Aortic Aneurysm Manifestations: DISSECTING
Sudden/severe/persistent “ripping” pain in anterior chest
Pain may extend to shoulder or abdomen
Pallor and sweating
Tachycardia
May have elevated BP and you may get different reading in the other arm
Syncope
Paralysis of lower extremities
Buerger’s Disease sxs
Bluish cast to toe or finger
“coldness” in affected limb
Nerve inflammation → severe pain
Blocked blood vessels → claudication as seen in PAD with accompanying symptoms
Ischemic ulcers and gangrene are common complications
Buerger’s Disease
nursing care
Nursing care
Smoking cessation
Vasodilators
calcium channel blockers for vasospasms
Monitor and treat pain
Provide emotional support
Raynaud’s Disease Manifestations
Triphasic color change after attack is triggered
Pallor
Cyanosis
Rubor
Pain
Skin thickening and nails become brittle
Raynaud’s Disease
nursing care
Keep hands warm (where gloves in cool environments)
Avoid stressful situations
Dissection of nerve fibers that allows vasoconstriction to relieve symptoms
Analgesics for pain
Vasodilators
Calcium channel blockers for vasospams
Thrombophlebitis Manifestations:

superficial
Palpable cordlike vein
Surrounding area warm, red, and tender
Edema
Arms (mostly like caused by IVs)
Legs (most likely a result of varicose veins
Thrombophlebitis Manifestations:
deep
Edema (location depends on what vein is occluded)
Pain
Warm skin
Homan’s sign (pain on dorsiflexion of foot)
PULMONARY EMBOLISM
SXS
Pink tinged sputum
Tachypnea
Tachycardia
SOB
Chest pain
Apprehension (feeling of impending doom)
Venous Insufficiency: manifestations
general
Edema of lower legs may extend to knees
Discoloration of skin (thick brown skin around ankles and feet)
Venous stasis ulcers
Venous Insufficiency: manifestations:
ARTERIAL
Skin is Pale
Minimal to no edema
Nails thick and brittle
Pain worse with elevation and exercise or even at rest
Pulses decreased or absence
Extremity temperature cool
Ulcers dry and necrotic
venous insufficiency:
VENOUS
Skin is ruddy cyanotic if dependent
Edema is present
Nails are normal
Pain is better with elevation and may increase throughout day
Pulses normal
Extremity temp is warm
Ulcers are moist
Infective Endocarditis : clin manifestations for BOTH acute and subacute
+ blood cultures
New cardiac murmur
Heart failure
Embolic complications
Roth spots (retinal hemorrhage)
Splinter hemorrhages
tiny lines that run vertically under nails
Embolic complications
Petechiae
Osler’s nodes
painful subcutaneous lesions in the distal fingers or toes
Janeway’s lesions
(painless hemorrhagic lesions on the palms and soles)
Infective Endocarditis : clin manifestations
ACUTE
Spiking fever and chills
Signs of heart failure
WBC elevation
Weakness
Infective Endocarditis : clin manifestations
SUBACUTE
Fever of unknown origin
Cough
Dyspnea
Anorexia
Malaise
Normal WBC
Anemia
Elevated ESR
Clubbing of fingers
Pericarditis Manifestations:
acute
Substernal pain radiating to the neck (sounds like angina!)
Dyspnea
Friction rub (scratchy high pitched sound on auscultation)
Elevated WBC
Fever/Malaise
ECG changes include ST and T wave elevations followed by inverted T waves when ST returns
Pericarditis Manifestations: chronic
Increasing dyspnea
Fatigue leading to progressive signs of heart failure
Mitral Valve Stenosis: sxs
Dyspnea
Occasionally accompanied by hemoptysis
Primary symptom because of reduced lung compliance
Palpitations from atrial fibrillation
Fatigue
Accentuated first heart sound (S1)
Low-pitched, rumbling diastolic murmur
Hoarseness
Chest pain
Seizures
Stroke
Mitral Valve Regurgitation:
SXS
Asymptomatic for years until development of some degree of left ventricular failure
Acute: Thready peripheral pulses and cool, clammy extremities
Initial symptoms include
Weakness
Fatigue
Palpitations
Dyspnea that gradually progresses to orthopnea, paroxysmal nocturnal dyspnea, and peripheral edema
Brisk carotid pulses
Auscultatory findings of accentuated left ventricular filling leading to audible S3
Murmur is loud pansystolic or holosystolic
Potassium: normal value
3.5-5.0
Calcium: norm value
8.4-10.2
NA sodium norm value
135-145
Mg+ magnesium norm value
2.5-4.5
Fe IRON norm value
65 - 150 mcg/dL
Chloride normal value
95 - 107
RBC normal value
4.6-5.5