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154 Cards in this Set

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What is the #1 cause of mental change in the elderly?
bladder infection- they go un-noticed and cause urosepsis, which leads to delirium
Acute Confusion
R/T disturbance of cerebral metabolism secondary to (any of the medical causes) AEB abrupt onset of disorientation, restlessness, incoherence, fear.
Is severe memory loss a normal part of aging?
No, Memory loss that progresses and significantly interferes with functioning is a sign of dementia.
With Delirium, why is it important to fix the underlying problem?
Because delirium can become permanent --> brain damage
Dementia is characterized by...
progressive deterioration of the intellectual functioning, memory, and problem solving abilities. In addition, insight and judgment, and moral/ethical behavior decline as well.
Does delirium happen slowly or suddenly?
Suddenly
Primary causes of dementias include...
Alzheimer’s Disease, Multi-infarct dementia, Pick’s disease, Huntington’s disease, Creutzfeldt-Jakob disease, ansLewy Body Disease
Secondary causes of dementia include...
Tuberculosis & other infections of the brain, Trauma, Metal poisoning, Korsakoff’s syndrome, AIDs related dementia
Huntington’s Disease
Genetic, autosomal dominant. Avg lifespan 15 yrs after onset, Deterioration of basal ganglia- uncontrolled movements, hallucinations, and delusions. Low GABA and ACh. No cure, can be found with genetic testing.
Symptoms of Huntington's disease?
Imbalance of Dopa and Ach (excessive Dopa) causes excessive movement- opposite of Parkinson's, as well as dementia
How is Huntington's Disease transmitted?
genetically- only need to inherit 1 gene. 50% chance of children inheriting disease if 1 parent carries Huntington’s (H) gene.
What is the different effect between inheriting Huntington's from mother or father?
Father- earlier onset, shorter lifespan
About what age does Huntington's disease usually come on?
30-50 (after already had children, too late!! probably passed it on)
What big ethical question does Huntington's bring up?
Should there be genetic testing done before having children (in utero) and then making the decision to have the child with disease or terminating the pregnancy
Creutzfeldt-Jakob disease (CJD)
deadly w/in 1-2 yrs, Confusion, loss of coordination, become unable to speak or move, mutated prion protein, "spongy brain"
3 ways to get Creutzfeldt-Jakob disease (CJD)
Inherited- genetic predisposition,
Acquired- ingest infected brain matter (mad cow)
Spontaneous mutation- most common way (85%)
Pick’s Disease
microscopic structures- “Pick’s bodies” are found and neurons “balloon," cannot function. Changes in frontal and anterior temporal lobes. Death w/in 5 yrs
Symptoms of Pick's Disease
changes of behavior, personality (apathy, disregard for social norms, loss of functionality), language changes- Eventually person becomes mute.
What disease is often mistaken for Alzheimer's?
Pick's Disease
Lewy Body Disease
abnormal protein deposits (lewy bodies) that disrupt the brain's normal functioning. Death 5-7 yrs
Lewy Body Symptoms
cognitive changes similar to Alzheimer’s Disease, and Parkinson type movement problems.
Alzheimer’s Disease Cause
Cause is unknown
Alzheimer’s Disease accounts for ____% of dementias.
5060
Risk for Alzheimer’s disease increases every five years after age ____.
65
Risk factor for Alzheimer’s
Age, heredity, heat disease
Heart disease interacts with early Alzheimer’s changes to...
multiply damage to the brain
Alzheimer’s mechanism of destruction?
The brain experiences destruction in which neurofibrillary tangles and plaques develop.
The cardinal symptoms of Alzheimer’s are:
Aphasia, Apraxia, Agnosia, Memory (Mnemonic)impairment, Disturbances in executive functioning
Aphasia
loss of language ability- both expressive and receptive, reading included
Apraxia
loss of purposeful movement in the absence of motor or sensory impairment. Not paralysis just cannot purposefully make body do what “you want” even though those movements are physically possible
Agnosia
loss of sensory ability to recognize objects- cannot feel a marker and know what it is even though they can physically feel the marker. All senses are affected.
Memory (Mnemonic)impairment
gradual loss of both recent and remote memory
Disturbances in executive functioning
difficulty with planning, organizing, abstract thinking. Cannot remember to keep appointments, etc.
Other symptoms of Alzheimer's?
Confabulation, Perseveration, Agraphia, Hyperorality, Hypermetamorphosis, Avoiding answering questions
Confabulation
making up stories to cover gaps in the memory (not intentionally lying- to maintain self-esteem)
Perseveration
repetition of phrases or behaviors
Agraphia
inability to read or write
Hyperorality
the need to put everything in one’s mouth
Hypermetamorphosis
touching everything
Avoiding answering questions
a way to maintain self-esteem…client “covers up” inability to answer.
4 stages of Alzheimer's
Mild: Forgetfulness
Moderate: Confusion
Moderate to Severe: Ambulatory dementia
Late: End stage
Signs of Mild Alzheimer's
Losses in short-term memory
Loses things by putting them in odd places
Uses memory aids
Denial of problems common
Signs of Moderate Alzheimer's
Memory losses apparent – forgets address &/or date
ADL’s suffer
Problems managing money, legal affairs
Mood labile
Withdraw from activities
Needs day care or in-home assistance
Signs of Moderate to Severe Alzheimer's
Doesn’t recognize family or objects (agnosia)
Forgets how to do activities such as walking, eating (apraxia).
Loses control of bowel and bladder
Wandering
Needs total assistance for all ADLs
May need placement in skilled care facility
Signs of Late Alzheimer's
Exhibits hypermetamorphosis & hyperorality
Does not recognize self anymore
Forgets how to eat
Loses ability to talk & walk
Prone to complications of immobility
Needs complete care
With Alzheimer's The average time from diagnosis to death is __ years, although some people may live up to __.
10 years,

20
Common Nursing diagnoses for pts with dementia
Risk for Injury and Chronic Confusion (also Self-care deficit syndrome and Caregiver role strain.)
Caregiver role strain
R/T unrelenting or complex care requirements secondary to progressive dementia, AEB depressed feelings, anger, and chronic fatigue
Managing Alzheimer's
No cure, drugs used delay decline but not prevent it.
What type of drugs used for Alzheimer's pts in early to moderate stages?
Cholinesterase Inhibitors- Aricept, Exelon, and Razadyne- Prevent break down of Ach (needed for memory)- delays worsening of symptoms
What type of drug is used in Alzheimer's pts in moderate to severe stages?
Namenda- limits axn (blocks receptors) of glutamate which can be destructive in the brain- protects neurons from being bombarded
Alz meds- cholinesterase inhibitors
Aricept, exelon, razadyne- prevent breakdown of ACh- increasing ACH improves cognition and behavior
Echolalia
repeats everything said
Illusions
errors in perception of sensory stimuli
Sundowning
symptoms and problem behaviors that become more pronounced in the evening
Reminiscence therapy
treatment to assist dementia patients to remember and increase brain function
Vascular dementia
dementia caused by CVA
Formulate teaching plans for clients and their families to assist them in providing care and making decisions about the care of the client with dementia.
Give information about community facilities, worry about murder suicide with care takers, must be patient, have to know that they will not get better.
ETOH level 0.05
1-2 drinks, Changes in mood/ behavior
ETOH level 0.10
5-6 drinks, voluntary actions Clumsy
ETOH level 0.20
10-12 drinks, Staggering, emotions labile
ETOH level 0.30
15-18 drinks, Confusion, stupor
ETOH level 0.40
20-24 drinks, Coma
ETOH level 0.50
25-30 drinks, Death d/t respiratory failure
coping styles used by addicted individuals
a. Denial, projection, rationalization, all or nothing thinking, conflict minimization, selective inattention, manipulation
Describe the problem of relapse in the recovery of clients with addictions
Relapses common during recovery. Goal of relapse prevention is to help the client learn from relapse so that periods of sobriety can be lengthened over time- lapses/relapses are not viewed as total failure
Discuss three therapeutic modalities used with clients with substance abuse problems
Support and kindness, set limits, maintain consistency, provide 411 about addiction as a chronic disease, encourage family therapy, reinforce disease concept
Blackout
A blackout is a phenomenon caused by the intake of alcohol or other substance in which long term memory creation is impaired or there is a complete inability to recall the past.
Al-Anon
support group for spouses and friends of alcoholics
Alcoholics Anonymous
self help group for recovering alcoholics
Co-dependence
coping behavior prevents from taking care of own needs, preoccupation with thoughts and feelings of other persons
Denial
escaping unpleasant realities by ignoring existence
Detoxification
treatment for coming off addictive substances to remove physiological effects
Dual diagnosis
psychiatric illness with an addiction or substance abuse
Disulfiram
antiabuse drug used for treatment of alcoholism causes nausea and vomiting if alcohol is ingested
Enabling
helping an addict avoid consequences of addiction
Flashbacks
occasional reoccurrence of perceptual disturbances caused by prior hallucinogenic drug use when clean
Intoxication
abnormal behavior or psychiatric changes due to use of alcohol or drugs
Narcan
medication to counteract narcotic effects
Polysubstance abuse
use of more than one drug or substance
Relapse
reoccurrence of disorder after period of improvement or returning to addictive substances when clean
Substance abuse
excessive use of drugs
Synergistic effect
adding effect when more than one med is taken, potentiates effects of one
Tapering
gradually becoming smaller
Tolerance
physiological decrease in reaction to a drug with repeated administrations of same dose
Wernicke
Wernike= acute decrease in thiamin. Causes acute confusion, ataxia, and neuropathy.
Korsakoff’s
Korsakoff= chronic decrease in thiamin, causes brain damage which leads to retrograde (from a point backward) and anterograde (from a point forward) amnesia
Wernicke-Korsakoff’s syndrome
Wernicke and Korsakoff's are actually one syndrome
Withdrawal
negative physiological and psychological reactions that occur when a drug is taken for a long time and is decreased in dose or no longer taken
Normal process of reward circuit
“Reward Circuit”- pleasure= release of dopa, Hippocampus & amygdala “remember” the good feeling, “Control center” evaluates & decides whether to repeat axn
Process of addiction
Drugs trick reward circuit, strong release of Dopa with drug, depletes Dopa so that "normal" experiences no longer bring pleasure- need for drug then overrides everything due to strong sense of reward
Recovery is difficult because of the ______ _____ associated with the drug.
lasting memories (cues in environment stimulate strong cravings)
50% of individual variation in susceptibility to addiction is _______
hereditary
__________ not fully developed in adolescents
Pre-frontal lobe...= less judgment = more chance of addiction.
Pain tolerance in cocaine & opioid abusers
Find in general that general population is much more pain tolerant than abusers; not sure if the person started out pain intolerant or the addiction caused it.
Good pain tolerant mice
good analgesia and no reward response – they didn’t like to take opioids for pleasure = good opioid binding.
Poor pain tolerant mice
= poor analgesia but loved reward – took opioids happily = poor opioid binding.
How to ask client's questions about drug use
Start with the least threatening questions: 1. Use of prescription drugs, 2. Use of over-the-counter drugs, 3. Use of social drugs, 4. Use of recreational drugs
Why is abstinence from drugs an important response to explore?
Need to know why – religious convictions or is the client a recovering addict
Physical signs of addiction
dilated/constricted pupils, abnormal vital signs, needle marks, tremors, alcohol on breath, confusion, staggering
Signs a person is intoxicated by CNS depressants
slurred speech, incoordination, staggering, drowsiness, inhibitions lowered resulting in impulsive sex and aggression, impaired judgment, social and occupational problems.
Alcohol related problems (medical)
ulcers, cirrhosis, pancreatitis, esophageal varices, malabsorbtion of vitamins (folic acid, vitamin B1, vitamin B12), cardiomyopathy, myopathies
Alcohol dulls the “_____ _______” by blocking neurotransmission
awake centers
What is the legal level of intoxication in CA?
.08%
2 types of alcohol w/drawal
What is the legal level of intoxication in CA?
A condition seen in chronic alcoholism is _______ _____ ______
Wernicke-Korsakoff syndrome
Wernicke-Korsakoff syndrome
result of a thiamine deficiency- addicts choose to drinking over eating- malnourished, damage to CNS and PNS
Wernicke’s disease
paralysis of eye movements, ataxia (wide based stance and slow uncertain short stepped gait), acute confusion
The signs and symptoms of Korsakoff’s disease often appears as the _______ is resolving.
confusion
Korsakoff’s disease
Combo antegrade and retrograde amnesia, confabulation is profound- hippocampus damaged D/T long term thiamine deficiency
Wernicke-Korsakoff syndrome treatments?
Admin thiamine IV or IM, for the malnutrition give MgSO4, K, and multivites
DO people bounce back from Wernicke-Korsakoff syndrome?
Recovery from effects of Wernicke-Korsakoff syndrome vary:
Mortality is 10-20%
Full recovery of ocular function usually occurs but 60% may have a persistent, fine horizontal nystagmus
40% recover from ataxia
20% recover from amnestic deficit.
Alcohol withdrawal- W/in a few hrs after last drink?
Symptoms peak and disappear ...?
see symptoms

24-48 hours after last drink
What does alcohol withdrawal look like?
See anxiety, anorexia, insomnia, tremors (shakes), illusions, confusion, increased BP & pulse, seizures
What environment needs to be provided for alcohol withdrawal?
Client needs calm, quiet, reassuring atmosphere, frequent reorientation
For alcohol withdrawal medicate with long lasting __________ to prevent seizures and progression to delirium tremens.
benzodiazepines (Librium)
Clonidine
anti-hypertensive agent
Used to reduce blood pressure in withdrawal
Also used to reduce acuity of withdrawal symptoms
Naltrexone
reduces alcohol craving and blocks euphoric effects of opiates
Antabuse
causes strong reaction when alcohol ingested; used for people to promote abstinence. MUST AVOID ALL ALCOHOL PRODUCTS
CIWA-A Assessment
Tool developed to monitor withdrawal symptoms
CIWA-A Assessment areas?
nausea & vomiting, tremors, sweats, anxiety, agitation, tactile/auditory/visual disturbances. Headache, orientation
How often to use the CIWA-A?
Every 4 hours during withdrawal
Alcohol withdrawal Delirium comes on when?
Starts 2-3 days after last drink
When pts experience delirium during alcohol withdrawal, is it a medical emergency?
Yes- Medical emergency, 20% mortality
How do pts usually die from delirium during alcohol withdrawal
Death usually due to cardiac problems, aspiration pneumonia, or hyperpyrexia
Signs & symptoms of alcohol withdrawal delirium
delirium, disorientation, visual and tactile hallucinations, paranoid delusions, agitation, raised vital signs
S/S of intoxication of opiates- opium, morphine, heroin
constricted pupils, decreased respiration, decreased BP, drowsiness, slurred speech, impaired memory and judgment
Complications of intoxication of opiates
overdose produces death through depressed respirations, other complications due to impurities in mixture
Opiates withdrawal signs
“Flu” – runny nose, aches, chills, fever; cramps, diarrhea, insomnia, diaphoresis, irritability
Drugs used to treat opiate withdrawal
methadone, naltrexone, Subutex, Clonidine
Methadone
a synthetic drug chemically similar to morphine. Used as heroine replacement for those wanting to stop using heroine. Less sedating, pt can function and live productive life, only admin qday
Marijuana (MJ) active ingredient
THC which has mixed depressant and hallucinogenic properties.
INTOXICATION: increased appetite, red eyes
s/s of MJ intoxication
increased appetite, red eyes, detachment, relaxation, euphoria, apathy, impaired memory & judgment.
s/s of MJ OD
can cause panic reactions
s/s of MJ dependence
associated with with lethargy, anhedonial, difficulty concentrating, memory impairment. This creates problems for kids in school. Also mimics depression.
5 As of smoking cessation
Ask, Advise, Assess, Assist and Arrange
Addictive coping styles tend to be predictable - use ______ _______ to avoid feeling badly about themselves.
defense mechanisms
Coping styles
defense mechanisms, denial, rationalization, All or nothing thinking, selective inattention, conflict minimization, MANIPULATION
RATIONALIZATION
justifying illogical ideas, actions, or feelings by developing an acceptable explanation for unacceptable behavior.
ALL OR NOTHING THINKING
inability to deal with parts of a situation.
SELECTIVE INATTENTION
only paying attention to parts of a situation or conversation.
CONFLICT MINIMIZATION
reducing the importance of an issue
MANIPULATION
getting people to do what you want.
Addicts have trouble giving up these coping styles. This interferes with their _______. Old behaviors reinforce _____ ______.
recovery

addictive lifestyle
Nurses Need to examine feelings
may be intolerant, hardened, or overly involved.
CODEPENDENCE
Nurses often come from homes with substance abuse and develop a life style of “saving” others.
ENABLING
supporting or denying the seriousness of the client’s substance abuse
Treat addiction like an _______ not moral failure
illness
Treatment programs
12 step programs, residential therapeutic communities, Intensive outpatient programs, family/marital therapy, long term med treatment
RESIDENDTIAL THERAPEUTAIC COMMUNITIES
Betty Ford
INTENSIVE OUTPATIENT PROGRAMS
VA
FAMILY & MARITAL THERAPY
life is often very dysfunctional due to client’s drug use. Need to rebuild trust & learn to live together. Also must change codependence patterns in family
Long term medication treatment
Antabuse, Revia, Subutex
C.A.G.E.- (Alcohol)
Have you ever felt....
(like you should) Cut Down
Annoyed
Guilty
Eye opener (wake up in morning needing a drink b4 can function)