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40 Cards in this Set
- Front
- Back
1. What is the usual cause of death in myocardial infarction?
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a. Infarct-induced ectopic focus
b. Sends heart into fibrillation |
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2. What is a type I MI?
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a. Spontaneous syndrome
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3. What is a type II MI?
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a. Infarction secondary to ischemia
b. Due to increased oxygen demand or decreased supply |
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4. What is a type III MI?
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a. Sudden, unexpected cardiac death
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5. What are types 4a, 4b, and 5 MI?
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a. MI associated with various procedures
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6. What are the elements of an MI dx?
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a. **Rise and fall of biochemical markers indicative of myocardial necrosis AND 1 of the following:
b. → ST changes, new Q waves c. Chest pain characteristic of AMI d. Imaging evidence of myocardium loss or regional wall motion abnormality |
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7. What chest pain is characteristic of an MI?
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a. Discomfort in chest, epigastric region, arm, wrist, and jaw
b. Lasts at least 20 minutes, may be shorter c. May develop centrally and radiate |
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8. With what symptoms can MI chest pain be associated?
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a. Dyspnea
b. Diaphoresis c. Nausea d. Vomiting e. Lightheadedness |
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9. How can an MI present in females?
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a. Upper abdominal pain
b. Dyspnea c. Nausea d. Fatigue |
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10. What can be absent in an MI in diabetic patients?
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a. Chest pain
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11. What does hypoxia cause in the heart muscle during an MI?
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a. Cell death
b. Lysis c. Spillage of enzymes into circulation |
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12. What enzymes are assayed for an MI?
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a. CK
b. LD |
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13. What is the relationship between amount of serum enzymes and severity of MI?
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a. The greater the levels of enzymes, the greater the extent of myocardial damage
b. The higher the level of enzymes, the lower the chance of survival |
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14. What are the different subtypes of LD?
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a. LD1- HHHH
b. LD2- MHHH c. LD3- MMHH d. LD4- MMMH e. LD5 MMMM |
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15. Where are the different subtypes of LD found?
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a. 1- Heart, kidney, RBC
b. 2- Heart, kidney, RBC c. 3- Lung, spleen d. 4- Liver, kidney, brain, skeletal muscle e. 5- Skeletal muscle, liver |
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16. What LD subtypes are especially elevated in cardiac muscle?
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a. LD2 and LD1
b. LD2>LD1 |
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17. What is the LD1:LD2 proportion in normal serum?
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a. LD1>LD2
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18. When does LD peak after an MI?
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a. 2 days after onset of chest pain
b. Remains elevated for 10-14 days |
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19. What are the major types of CK?
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a. MM
b. MB c. BB |
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20. Where are the major types of CK found?
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a. MM- skeletal and cardiac muscle; major form
b. MB- cardiac muscle, trace in skeletal c. BB- brain; only isoform in CSF |
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21. When will CK be elevated in relationship to MI?
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a. 3 to 4 hours after onset of chest pain
b. 12-24 hours most sensitive and specific for MI |
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22. How do you calculate the CK index?
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a. (CK-MB)/total CK
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1. What does an elevated CK index indicate?
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a. CK-MB is probably cardiac as opposed to skeletal
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24. What does a high CK-MB with a low CK index indicate?
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a. Other muscular damage
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25. What is elevated in a subendocardial infarction?
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a. Large amounts of CK2 (MB) are released
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26. What leads to necrosis in a subendocardial infarction?
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a. Oxygen free radicals
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27. What is released in a total occlusion of the coronary arteries?
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a. Lower levels of MB
b. Appear later, remain subsequently elevated |
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28. When will myoglobin levels be elevated after an MI?
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a. 1-3 hours
b. **Not a specific marker |
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29. What does the presence of cTnt and cTnI indicate?
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a. Myocardial insult
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30. When does cTnT appear after an MI? Peak? How long does it remain elevated?
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a. Increase at 3-4 hours after MI
b. Peak at 10-24 hours c. Remain elevated for 10-14 days |
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31. When does cTnI appear after an MI? Peak? How long does it remain elevated?
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a. Increase 4-6 hours after MI
b. Peak at 10-24 hours c. Remain elevated for 4-7 days |
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32. What is the dx value of MB?
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a. Reinfarction
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33. What is the dx value of CK-MB?
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a. Early thrombolytic tx
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34. What is the dx value of cTnI and cTnT?
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a. All types of insult
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35. What is the dx value of LD1?
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a. Late-admitted patients
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36. What enzyme is elevated in 100% of MI patients?
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a. LD1
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37. What is the usefulness of an LD1 test?
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a. Dx of an MI which might have occurred several days earlier
b. May not have resulted in immediate hospitalizations c. **CONSIDERED A CONFIRMATORY TEST** |
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38. A patient has had an MI if he/she has an elevated CK-MB/CK index and…
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a. 1+ elevated cardiac marker
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39. What is the dx value of myoglobin?
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a. Early dx marker for AMI
b. Reinfarction of a patient with previously confirmed MI or surgery-induced infarct |
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40. How high to cTn levels rise in classic AMI?
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a. 20 to 50 times
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