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15 Cards in this Set
- Front
- Back
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M tuberculosis treatment
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RIPE: rifampin, isoniazid, pyrazinamide, ethambutol
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M avium treatment
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azithromycin, rifampine, ethambutol, streptomycin
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M TB prophylaxis
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INH
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M avium prophylaxis
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azithromycin
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M leprae treatment
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dapsone, rifampin, clofazimine
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pyrazinamide is effective where?
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in acidic pH of phagolysosomes
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MOA ethambutol
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block arabinosyltransferase --> decrease carb polymerization of cell wall
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SE of ethambutol
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optic neuropathy: color blindness
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MOA of INH
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decrease synthesis of mycolic acids
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what is needed to activate INH?
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bacteria catalase peroxidase
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SE of INH?
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neurotox, hepatotox, lupus
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what is given w/ INH?
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vit b6
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4 Rs of Rifampin
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RNA pol inhibitor, Revs up p450, Red/orange fluids, Rapid resistance if used alone
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prophyalxis of meningococcal infection
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rifampin
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prophyalxis of endocarditis
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penicillins
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