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20 Cards in this Set
- Front
- Back
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what class are mycobacterium tuberculosis
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rod shaped aerobic
ACID FAST(red on blue background) |
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what are some diseases caused by mycobacterium
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TB and leprosy
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what species of mycobacterium cant be grown on agar
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m. laprae
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where are mycobacteria found
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transmission from the environment
grow in macrophages in host |
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how long does it take for m. tuberculossis to grow on agar
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weeks
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what are the characters of nocardia
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filiments long rods with branching
ACID FAST intracellular in macrophages |
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what does nocardia cause
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TB like disease
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what is the character of rhodococcus qui
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short rods and cocci
ACID FAST causes TB like disease |
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what are the characteristics of m. tuberuclosis
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slender, straight or crved rods, filamnets
ACID fast stain |
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what are the virulence factors fo m. tuberculosis
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obligate aerobe
intracellular growth in macrophages |
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what is the PPD
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purified protien derivative that u develop antibodies to if u have TB
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what make mycobacterial acid fast
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the long chain glucocarbohydrate acids
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how is TB transmitted
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person to person by inhalation of droplets, survives for long periods in air and surfaces
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what are the clincal aspect of TB
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primary infectino-latent asymptomacit
spreads to lymph nodes then to blood to spleen and liver still asymptomatic immune system kicks in then granulomatous inflammations occurs everywhere TB is located in the body. |
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what is reinfection TB
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the causeating granulomas filled with TB burst and respread the infection
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what are symptoms of TB
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fever fatigue, anorexia, cough,
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what is miliary TB
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when the TB spreads everywhere brain, menegies etc.
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diagnosis of M. tuberculosis
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first check for acid fast
culture-take weeks PPD checks immune status quantiferon-TB dont have to come back PCR used to confirm after acid fast test |
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what is the treatment for TB
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1. isoniazid, rifapmin, pyrazinamid
2. fluorquinolones, aminoglycosides MDRstrain- resistan to at least 2 first ling xDR strains- resistant to 2nd line |
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prevention of TB
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isoniazid prevention prophalaxis
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