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5 Cards in this Set
- Front
- Back
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PCOD
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poly cystic ovarian disease
-multiple follicular cysts in ovary due to hormone imbalance -due to inc LH and low FSH LH:FSH ratio >2 **key problem is inc. LH |
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PCOD
-pathophys |
hirsutism - due to excess LH and androgen production
-excess androgens converted to estrone at peripheral adipose tissue (obese patients) -excess estrone inhibits ant. pit. to secrete less FSH -dec FSH causes granulosa cells to degenerate, and the follicles degenerate and become cystic (due to not enough estrogen from granulosa cells) |
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PCOD
-presentation |
-obese young women with infertility
-oligomenorrgea -hirsutism -insulin resistance -high circulating estrone levels inc risk for endometrial carcinoma |
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Polycystic ovaries
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-Associated with inc. luteinizing hormone
- Stimulates thecal-lutein cells to make androgen |
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Polycystic ovaries
-morphology |
-Multiple small follicle cysts
-Hyperplasia of lining cells (theca interna |
