Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
20 Cards in this Set
- Front
- Back
|
A group of inflammatory pruritic skin disorders. Etiology: allergy (usually type IV hypersensitivity), chemical injury, or infection.
|
Dermatitis
|
|
|
Pruritic eruption, commonly on flexor surfaces. Often associated with other atopic diseases (asthma, allergic rhinitis).
|
Atopic dermatitis (eczema)
|
|
|
Type IV hypersensitivity reaction that follows exposure to allergen (poison ivy, poison oak, nickel, rubber, chemicals). Lesions occur at site of contact.
|
Allergic contact dermatitis
|
|
|
Epidermal hyperplasia (acanthosis) with parakeratotic scaling (nuclei still in stratum corneum) especially on knees and elbows. ↑ stratum spinosum, ↓ stratum granulosum. Auspitz sign.
|
Psoriasis
|
|
|
Auspitz sign
|
Psoriasis
-punctuate bleeding b/c you took off outer layer |
|
|
Pruritic papules and vesicles. Associated with celiac disease.
|
Dermatitis herpetiformis
|
|
|
Pruritic, purple, polygonal papules; infiltrate of lymphocytes at dermoepidermal junction.
|
Lichen planus
|
|
|
Associated with infections, drugs, cancers, and autoimmune disease. Presents with
multiple types of lesions, including macules, papules, vesicles, and target lesions (red papules with a pale central area). |
Erythema multiforme
|
|
|
Major form of Erythema multiforme
|
Stevens-Johnson syndrome is the major form of erythema multiforme. Characterized by high fever, bulla formation and necrosis, ulceration of skin, and a high mortality rate.
|
|
|
Flat, pigmented squamous epithelial proliferation with keratin-filled cysts (horn cysts).
Benign. |
Seborrheic keratosis
|
|
|
Caused by sun exposure. Small, rough erythematous or brownish papules. Premalignant lesion. Risk of carcinoma is proportional to epithelial dysplasia.
|
Actinic keratosis
|
|
|
Tumor of connective tissue elements of dermis that causes raised, thickened scars.
Follows trauma to skin, especially in African-Americans. |
Keloid
|
|
|
Autoimmune disorder with IgG antibody against epidermal basement membrane (linear immunofluorescence). Similar to but less severe than pemphigus vulgaris––affects skin but spares oral mucosa
|
Bullous pemphigoid
|
|
|
Potentially fatal autoimmune skin disorder. Intradermal bullae involving the oral mucosa and skin. Findings: acantholysis (breakdown of epithelial cell-to-cell junctions), IgG antibody against epidermal cell surface(immunofluorescence throughout epidermis)
|
Pemphigus vulgaris
|
|
|
_____ precursor to Squamous cell carcinoma
|
Actinic keratosis
|
|
|
Very common. Associated with excessive exposure to sunlight and arsenic exposure. Commonly appear on hands and face. Locally invasive, but rarely
metastasizes. Histopathology: keratin “pearls” |
Squamous cell carcinoma
|
|
|
Most common in sun-exposed areas of body. Locally invasive, but almost never metastasizes. Gross pathology: pearly papules
|
Basal cell carcinoma
|
|
|
____ have “palisading” nuclei.
|
Basal cell carcinoma
|
|
|
______is a precursor to Melanoma
|
Dysplastic nevus
|
|
|
Common tumor with significant risk of metastasis. Associated with sunlight exposure; fair-skinned
persons are at ↑ risk. Incidence ↑. Depth of tumor correlates with risk of metastasis |
Melanoma
|
