Musculoskeletal Pharma

Front 1

opoid for pain, cough suppression

Back 1

dextromethorphan

Front 2

opoid for diaarhea

Back 2

loperamid and diphenoxylate

Front 3

toxicity includes respiratory depression, constipation, miosis

Back 3

opoid analgesics

Front 4

inhibits phopholipase a2

Back 4

coricosteroids

Front 5

inhibits lipoxygenase

Back 5

zileuton

Front 6

inhibits secretions of leukotrienes

Back 6

zafirlukast
montelukast

Front 7

inhibits cox

Back 7

nsaids
acetominophen
cox-2 inhibitors

Front 8

pg that decreases platelet aggregation and tone

Back 8

PGI

Front 9

pg that increases platelet addregagion and vascular tone

Back 9

thromboxane

Front 10

pg that increases uterine tone and decreases vascular tone

Back 10

pge, pgf

Front 11

close pda

Back 11

indomethacin

Front 12

cox found in inflammatory cells that mediates inflammation and pain

Back 12

cox-2

Front 13

cox that maintains gastric mucosa

Back 13

cox-1

Front 14

toxicity includes hepatic necrosis, depletion of glutathione

Back 14

acetominophen

Front 15

anicdote for acetominaphen and action

Back 15

n-acetylcystein- regenerates glutathione

Front 16

gout treatment that inhibits xanthine oxidase

Back 16

allopurinol

Front 17

gout treatment that inhibits tubular reabsorption of uric acid

Back 17

probenecid

Front 18

gout treatment that depolymerizes microtubules

Back 18

colchicine

Front 19

gout treatment that inhibits secretion of penicillin

Back 19

probenecid

Front 20

use in lymphoma to prevent "tumor-lysis syndrome"

Back 20

allopurinol

Front 21

tnf receptor that binds tnf alpha

Back 21

etanercept

Front 22

used for RA, psoriasis, AS

Back 22

etanercept

Front 23

tnf alpha antibody

Back 23

infliximab

Front 24

used for chron's, ra, as

Back 24

infliximab

Front 25

inhibits calcineurin

Back 25

cyclosporine and tacrolimus

Front 26

suppresses organ rejection after transplantation

Back 26

cyclosporine

Front 27

potent immunosuppressive used in organ transplant recipients

Back 27

tacrolimus

Front 28

predisposes to viral infections and lymphomas

Back 28

cyclosporine

Front 29

to prevent cyclosporine nephrotoxicity

Back 29

mannitol diuresis

Front 30

toxicities are nephrotoxicity, peripheral neuropathy, hypertension, pleural effusion, hyperglycemia

Back 30

tacrolimus

Front 31

used with kidney transplantation and autoimmune disorders

Back 31

azathioprine

Front 32

metabolized by xanthine oxidase

Back 32

azathioprine

Front 33

6mercaptopurine derivative toxic to proliferating lymphocytes

Back 33

azathioprine

Front 34

cytokine used for renal cell ca and metastatic melanoma

Back 34

aldesleukin (interleukin-2)

Front 35

recombinant il-2

Back 35

aldesleukin

Front 36

recombinant erythropoiein

Back 36

epoeitin - for anemias, especially in renal failure

Front 37

recombinant granulocyte-csf

Back 37

filgastrim, sargramostim - to recover bm

Front 38

recombinant cytokines used for hep b and c, kaposi's, leukemia, and malignant melanoma

Back 38

alpha interferon

Front 39

recombinant cytokine for multiple sclerosis

Back 39

beta interferon

Front 40

cytokine used for chronic granulomatous disease

Back 40

gamma interferon

Front 41

cytokine to treat thrombocytopenia

Back 41

oprelvekin (il-11) and thrombopoietin

Front 42

cytokine used for chronic granulomatous disease

Back 42

gamma interferon

Front 43

cytokine to treat thrombocytopenia

Back 43

oprelvekin (il-11) and thrombopoietin