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6 Cards in this Set

  • Front
  • Back
What is Achondroplasia?
Auto dominant, early sealing off between epiphysis & metaphysis. Sx= leg bowing, hearing loss, sciatica, infantile hydrocephalus
What is McCune-Albright's syndrome (polyostotic fibrous dysplasia)?
Idiopathic replacement of bone with fibrous tissue + precocious puberty + cafe au lait spots
What are the signs of Osteogenesis Imperfecta?
1) BLUE SCLERA
2) Brittle weak bones
3) Dental imperfections
4) Hearing loss

* all due to defective collagen synthesis
What is Osteopetrosis (Marble Bone Disease)?
1) Markedly inc. bone density due to OSTEOCLASTIC failure
2) Weak bone easily fractured
3) Pancytopenia due to dec. marrow space
4) Cranial nerve dysfunction due to impinged foramina
What causes Pyogenic Osteomyelitis?
1) S. aureus most common
2) S. agalactiae and E. coli in newborns
3) Salmonella in sickle cell anemics
4) Pseudomonas in IVDU's
Where does Pyogenic Osteomyelitis usuallly affect?
1) Metaphysis, distal head of femur, proximal tibia, proximal humerus
2) X-ray show periosteal elevation