Musculoskeletal Diseases Of The Skin

Front 1

What is a circumscribed lesion of < 5mm diameter characterized by FLATNESS & usually distinguished from surrounding skin by its COLORATION?

Back 1

Macule

Front 2

What is a circumscribed lesion of > 5mm diameter characterized by FLATNESS & usually distinguished from surrounding skin by its COLORATION?

Back 2

Patch

Front 3

What is an elevated dome-shaped or flat-topped lesion < 5mm in diameter?

Back 3

Papule

Front 4

What is an elevated lesion with spherical contour > 5mm in diameter?

Back 4

Nodule

Front 5

What is an elevated flat-topped lesion, usually > 5mm in diameter

Back 5

Plaque

Front 6

What is a Fluid-filled raised lesion < 5mm in diameter?

Back 6

Vesicle

Front 7

What is a Fluid-filled raised lesion > 5mm in diameter?

Back 7

Bulla

Front 8

What is a common term used for either a vesicle or bulla?

Back 8

Blister

Front 9

What is a discrete, puss-filled, raised lesion?

Back 9

Pustule

Front 10

What is an itchy, transient, elevated lesion with variable blanching and erythema formed as the result of dermal edema

Back 10

Wheal

Front 11

What is a drym horny, platelike excresence, usually the result of imperfect cornification?

Back 11

Scale

Front 12

What is a thickened and rough skin characteried by prominent skin markings; can be the result of repeated rubbing?

Back 12

Lichenification

Front 13

What is a traumatic lesion characterized by breakage of the epidermis causing a raw linear area; often self-induced?

Back 13

Excoriation

Front 14

What is a separation of the nail plate from the nail bed?

Back 14

Onycholysis

Front 15

What is the theckening of the stratum corneum, often associated with a qualitative abnormality of the keratin?

Back 15

Hyperkeratosis

Front 16

What is a diffuse epidermal hyperplasia?

Back 16

Acanthosis

Front 17

What is a surface elecation caused by hyperplasia and enlargemnet of contiguous dermal papillae?

Back 17

Papillomatosis

Front 18

What is an abnormal keratinization occurring prematurely within individual cells or groups of cells below the stratum granulosum?

Back 18

Dyskeratosis

Front 19

What is a loss of intercellular connections resulting in loss of cohesion between keratiocytes?

Back 19

Acantholysis

Front 20

What is intercellular edema of the epidermis?

Back 20

Spongiosis

Front 21

What is infiltration of the epidermis by inflammatory or circulating blood cells?

Back 21

Exocytosis

Front 22

What is discontinuity of the skin exhibiting INcomplete loss of the epidermis?

Back 22

Erosion

Front 23

What is discontinuity of the skin exhibiting Complete loss of the epidermis and often portions of the dermis and even subcutaneous fat?

Back 23

Ulceration

Front 24

What is a linear pattern of melanocyte proliferation within the epidermal basal cell layer?

Back 24

Lentiginous

Front 25

What are the ABC's that differentiate Nevocellular nevus from melanomas in pigmented lesions?

Back 25

Assymetry
Border Irregularity
Color Variability
Diameter > 6mm
Enlargement- increase in size

Front 26

T/F
Congenital nevi carry decreased risk for development into melanoma.

Back 26

False
Increased Risk

Front 27

What condition presents clinically as:
Waxy, tan to dark brown plaque
Arise spontaneously and may be solitary or multiple
May be difficult to distinguish from melanoma clinically
May occur explosively in large numbers, as part of paraneoplastic syndome (LESER-TRELAT sugn)

Back 27

Seborrheic Keratosis
(benign epithelial tumor)

Front 28

What condition presents clinically as:
Flesh colored, dome shaped nodule with a central erosion
Predilation for dacial skin, including the cheeks nose and ears and the dosa of the hands
RAPID GROWTH RATE and spontaneous remission differentiate keratocanthoma from squamous cell carcinoma

Back 28

Keratocanthoma

Front 29

What are two types of malignant epithelial tumors?

Back 29

Squamous cell carcinoma & Basal cell carcinoma

Front 30

What presents clinically as:
A malignant neoplasm of keratinocytes
2nd most common skin cancer
Rarely metastisize
Nodule or plaque +/- ulceration
Risk factors: sun exposure, skin type, immunosuppression, HPV infection, chronic inflammation, industrial carcinogens

Back 30

Squamous cell carcinoma

Front 31

What condition presents clinically as:
A malignant neoplasm of basal keratinocytes
Most common type of skin cancer
Pearly papule or nodulecontaining prominant dilated subepidermal blood vessels +/- ulceration
Risk factors: sun exposure, skin type, immunosuppression
Locally invasive, slow-growing tumors that rarely metasticize

Back 31

Basal cell carcinoma

Front 32

What condition is characterized by urticaria & erythema multiforme?

Back 32

Acute Inflammatory Dermatoses

Front 33

What condition is characterized by psoriasis, seborrheic dermatitis, lichen planus?

Back 33

Chronic Inflammatory Dermatoses

Front 34

What has lesions that last from days to weeks.
Inflammation & edema +/- epidermal, vascular or subcutaneous injury.
Diagnosis requires combination of clinical and pathologic findings?

Back 34

Acute Inflammatory Dermatoses

Front 35

What condition persists for months to years
In addition to inflammation these lesions often show significant components of altered epidermal growth (atrophy or hyperplasia) +/- dermal fibrosis
Diagnosis requires combination of clinical and pathologic findings?

Back 35

Chronic inflammatory dermatoses

Front 36

What consists of transient, slightly erythematous pruritic papules and edematous plaques (wheals)

Back 36

Urticaria

Front 37

What is a blistering disorder of adults characterized by superficial vesicles and bullae that are easily ruptured. Autoimmune, detected by direct immunofluorescence. Antibodies form against a component of desmosomes (desmoglein 3)?

Back 37

Pemphigus vulgaris

Front 38

What is a distinct vesicobullous disease affecting elderly individuals characterized by formation of tense bullae?

Back 38

Bullous Pemphigoid

Front 39

What is a chronic inflammatory dermatosis that has macules and papules on an erythematous, often greasy base +/- scaling and crusting?

Back 39

Chronic dermatoses
(dandruff)

Front 40

What is a common, chronic, T-cell mediated inflammatory deramatosis?

Back 40

Chronic Dermatoses

Front 41

What condition is a self-limiting, chronic inflammatory dermatosis of unknown etiology?

Back 41

Lichen Planus

Front 42

What presents as white dots or lines associated with chronic dermatoses?

Back 42

Wickham Striae

Front 43

What is an uncommon self-limited disorder that appears to be a hypersensitivity reaction to certain infections and drugs?

Back 43

Erythema multiforme

Front 44

***What is the most common fatal malignancy among young adults?

Back 44

Melanoma: a malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule.

Front 45

***What disease may occur explosively in large numbers, as part of a paraneoplastic syndrome (Leser-Trélat sign)?

Back 45

Seborrheic Keratoses - this could indicate a neoplasm in the GI tract

Front 46

***What differentiates Keratocanthoma from Squamous cell carcinoma?

Back 46

Rapid Growth Rate

Front 47

***What is the 2nd most common skin cancer and is primarily attributed to the sun?

Back 47

Squamous Cell Carcinoma

Front 48

***What is the Most common type of skin cancer and is primarily attributed to the sun?

Back 48

Basal Cell Carcinoma

Front 49

***What are the 4Ps of Lichen Planus?

Back 49

Pruritic (itchy)
Purple
Polygonal
Papules