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18 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Glycopyrrolate (MOA & PK)
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MOA - Reversibly inhibits ACh binding to muscarinic receptors
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PK - IV; quartenary amine
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Glycopyrrolate (CU & T)
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CU - IBS; minor diarrhea; block muscarinic effects in periphery
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T - Decreased sweating and lacrimation, elevation of body temp, tachycardia, constipation, dry mouth, and blurred vision+ mydriasis, sedation, amnesia, delirium or hallucinations, heart arrhythmias, cutaneous vasodilation; reduced CNS effects
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Mepenzolate (MOA & PK)
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MOA - Reversibly inhibits ACh binding to muscarinic receptors
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PK - PO; quartenary amine
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Mepenzolate (CU & T)
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CU - IBS; minor diarrhea; block muscarinic effects in periphery
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T - Decreased sweating and lacrimation, elevation of body temp, tachycardia, constipation, dry mouth, and blurred vision+ mydriasis, sedation, amnesia, delirium or hallucinations, heart arrhythmias, cutaneous vasodilation; reduced CNS effects
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Methscopolamine (MOA & PK)
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MOA - Reversibly inhibits ACh binding to muscarinic receptors
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PK - PO; quartenary amine
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Methscopolamine (CU & T)
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CU - IBS; minor diarrhea; block muscarinic effects in periphery
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T - Decreased sweating and lacrimation, elevation of body temp, tachycardia, constipation, dry mouth, and blurred vision+ mydriasis, sedation, amnesia, delirium or hallucinations, heart arrhythmias, cutaneous vasodilation; reduced CNS effects
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Tridihexethyl (MOA & PK)
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MOA - Reversibly inhibits ACh binding to muscarinic receptors
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PK - PO; quartenary amine
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Tridihexethyl (CU & T)
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CU - IBS; minor diarrhea; block muscarinic effects in periphery
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T - Decreased sweating and lacrimation, elevation of body temp, tachycardia, constipation, dry mouth, and blurred vision+ mydriasis, sedation, amnesia, delirium or hallucinations, heart arrhythmias, cutaneous vasodilation; reduced CNS effects
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Clindinium (MOA & PK)
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MOA - Reversibly inhibits ACh binding to muscarinic receptors
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PK - PO; quartenary amine
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Clindinium (CU & T)
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CU - IBS; minor diarrhea; block muscarinic effects in periphery
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T - Decreased sweating and lacrimation, elevation of body temp, tachycardia, constipation, dry mouth, and blurred vision+ mydriasis, sedation, amnesia, delirium or hallucinations, heart arrhythmias, cutaneous vasodilation; reduced CNS effects
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Trospium (MOA & PK)
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MOA - Reversibly inhibits ACh binding to muscarinic receptors
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PK - PO/PR/IV; quartenary amine
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Trospium (CU & T)
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CU - IBS; minor diarrhea; block muscarinic effects in periphery
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T - Decreased sweating and lacrimation, elevation of body temp, tachycardia, constipation, dry mouth, and blurred vision+ mydriasis, sedation, amnesia, delirium or hallucinations, heart arrhythmias, cutaneous vasodilation; reduced CNS effects
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Propantheline (MOA & PK)
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MOA - Reversibly inhibits ACh binding to muscarinic receptors
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PK - PO; quartenary amine
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Propantheline (CU & T)
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CU - IBS; minor diarrhea; block muscarinic effects in periphery
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T - Decreased sweating and lacrimation, elevation of body temp, tachycardia, constipation, dry mouth, and blurred vision+ mydriasis, sedation, amnesia, delirium or hallucinations, heart arrhythmias, cutaneous vasodilation; reduced CNS effects
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Ipratropium (MOA & PK)
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MOA - Reversibly inhibits ACh binding to muscarinic receptors
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PK - Inhaled; quartenary amine
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Ipratropium (CU & T)
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CU - Asthma and COPD
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T - Decreased sweating and lacrimation, elevation of body temp, tachycardia, constipation, dry mouth, and blurred vision+ mydriasis, sedation, amnesia, delirium or hallucinations, heart arrhythmias, cutaneous vasodilation; reduced CNS effects
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Tiotropium (MOA & PK)
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MOA - Reversibly inhibits ACh binding to muscarinic receptors
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PK - Inhaled; longer duration than ipratropium; quartenary amine
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Tiotropium (CU & T)
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CU - Asthma and COPD
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T - Decreased sweating and lacrimation, elevation of body temp, tachycardia, constipation, dry mouth, and blurred vision+ mydriasis, sedation, amnesia, delirium or hallucinations, heart arrhythmias, cutaneous vasodilation; reduced CNS effects
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