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ANGINA PECTORIS
Fall '09
Here we go!
First of all, what is Angina Pectoris?
Angina Pectoris:
Sudden pain beneath the sternum often radiating to left shoulder and arm; Oxygen supply to the heart is insufficient to meet oxygen demand
We know of 3 types of Angina.
What are they?
Types of Angina:
Chronic stable angina (exertional) which increases O2 demand
Variant angina (Prinzmetal’s) which decreases O2 supply
Unstable angina
3 Familiar antianginal agents that are often prescribed:
3 Familiar antianginal agents:
Organic nitrates
Beta blockers (not for variant angina)
Calcium channel blockers
Fill In The Blank
Ready?!
_____________ is a Nitrate. It is a ___________ of VSM.
NITROGLYCERIN is a Nitrate. It is a vasodilator of VSM
Adverse effects for Nitroglycerin are
Headache, ___________ hypotension, Reflex ___________.
Adverse effects for Nitroglycerin are
Headache, Orthostatic hypotension, Reflex Tachycardia.
Routes of administration for this Nitrate are __________, oral sustained-release, ___________, translingual spray, buccal, _______, and IV.
Routes of administration for this Nitrate are sublingual, oral sustained-release, transdermal, translingual spray, buccal, topical, and IV.
NEXT, is Beta Blocker (decreases _______ O2 ______) PROPRANOLOL. This is not effective against _______ angina.
Next, is Beta Blocker (decreases cardiac O2 demand) PROPRANOLOL. This is not effective against variant angina.
Propanolol's adverse effects are:
~______cardia
~Decreased __ conduction
~Reduction of _____________
~As___tic effects
~Caution with ________
Propanolol's adverse effects are:
~Bradycardia
~Decreased AV conduction
~Reduction of contractility
~Asthmatic effects
~Caution with *diabetes
LAST, Ca+ Channel Blockers that we have learned are Verapamil, diltiazem, and __________ which are used to ______ arterioles for stable and ______ angina. Adverse effects are ___________, reflex tachycardia, and Bradycardia.
LAST, Ca+ Channel Blockers that we have learned are Verapamil, diltiazem, nifedipine which are used to dilate arterioles for stable and variant angina. Adverse effects are hypotension, reflex tachycardia, and Bradycardia.