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20 Cards in this Set
- Front
- Back
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MS is a chronic, progressive disease of the immune system based around _________ of the nerves of the brain and spinal cord
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Demyelination
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4 early symptoms of MS?
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Weakness, tingling, numbness, blurred vision
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4 Interferon-Beta drugs for MS
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1.) betaseron
2.) avonex 3.) rebif 4.) extavia |
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Copaxone generic name
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Glatiramer Acetate
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__________= humanized monoclonal antibody that targets alpha-4 integrin
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Natalizumab (Tysabri)
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Which MS drug is pregnancy category X?
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Betaseron
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Prior to immune modulator therapy, which vaccine should be considered?
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Varicella (shingles shot)
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Special handling instruction for ALL interferons?
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Do NOT shake
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All interferons are C/I if?
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hypersensitivity reaction to any of them
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2 interferons with albumin in them?
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Avonex
Extavia |
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Glatiramer acetate (Copaxone) dosing?
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20 mg SQ daily
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Common S/E of Copaxone?
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Chest pain/tightness
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________ has the TOUCH program due to risk of progressive multifocal leukoencephalopathy (PNL)
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Natalizumab (Tysabri)
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How is Tysabri given?
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IV
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_________ is an ORAL immune modulator
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Gilenya (fingolimod)
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Required baseline monitoring for Gilenya?
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ECG
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Potassium-channel blocker used for MS?
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Dalfampridine (Ampyra)
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Dose for dalfampridine (Ampyra)?
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10 mg PO BID
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2 C/I for Ampyra?
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1.) History of seizures
2.) CrCl < 50 ml/min |
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8 sites for SQ injection?
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R/L abdomen, R/L upper back arm, R/L buttocks, R/L thighs
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