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17 Cards in this Set

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Non ulcer dyspepsia is basically a gray area

and dx of exclusion

it can only be diagnosed by EGD

but the mgmt is to just start a trial of PPI and track for improvement

there is no definitive

symptomatology for non ulcer dyspepsia

when DO you scope for non ulcer dyspepsia?

if the pt has epigastric pain, non-defining symtoms and they have FAILED a PPI trial then it's worth scoping because you have to rule out gastritis, PUD, etc.

what age is EGD definitely not indicated for with just vague epigstric pain/

under age 45

AT what age SHOULD any patient with epigastric pain undergo EGD?

over 55



if it's new onset dyspepsia over age 55 then it's more concerning for cancer bc this is weird

so basically age over 55 is yet another

alarm symptom

IF symptoms have not resolved and you ahve confirmed NUD by EGD what is the next step in mgmt?

you should treat empirically for HP with triple therapy even though the evidence of benefit is limited

NUD is basically epigastric pain with

normal EGD findings

how many ulcers are due to Zollinger Ellison syndrome?

less than 1%

features of ulcers taht would suggest a gastrinoma

large


recurrent even after H pylori eradication


distal in the duodenum


multiple



also associated with diarrhea symptoms from the abnormally high acid and subsequent activation of lipase

the confirmatory test for gastrinoma is...

high gastrin levels even with high gastric acidity (when PPIs are stopped)



there should normally be negative feedback to inhibit gastrin production/release

persistently high gastrin despite secretin injection

high gastrin despite measured high gastric acid output

the most accurate test for gsatrinoma is...

looking at the response to secretin

If a patient with a gastrinoma also had hypercalcemia

you would suspect MEN 1 syndrome

the next step after dx of a gastrinoma is to rule out

metastatic disease with CT/MRI

If the CT and MRI are normal then what should you do?

then you should perform nuclear scintigraphy with somatostatin.