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12 Cards in this Set
- Front
- Back
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how would you suspect hyperaldosteronism going on? |
HTN, high aldo levels, low renin activity (PRA) |
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what is the most common cause of PRIMARY hyperaldosteronism? |
a solitary adenoma |
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when in real life might you suspect an adrenal adenoma causing HTN? |
if it's not controlled with 2 meds in patients under age 30 if there is hypokalemia or other big lab clues |
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so sometimes we pick up an adenoma |
incidentally in association with hypokalemia |
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what is the best initial test when looking for Conn syndrome? |
to perform a plasma aldosterone to plasma renin ratio |
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if you see high renin, then |
you can exclude primary hyperaldosteronism from your DDx |
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How do you determine whether the lesion is uni or bilateral? |
you can do venous sampling from the adrenal gland. |
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what imaging modality is used to evaluate for primary hyperaldosteronism? |
CT scan of the adrenals- but it's only done to confirm suspicion with a) hypokalemia b) high aldosterone despite a high salt intake and c) low plasma renin level |
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CT scan is the |
last step in dx |
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what is the treatment for primary hyperaldosteronism? |
a unilateral adenoma is resected laparoscopically |
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What if the hyperaldosteronism is from bilateral hyperplasia? |
then you have to treat it medically with EPLERENONE OR SPIRONOLACTONE |
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What is eplerenone/spironolactone |
they are mineralocorticoid antagonists |
