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26 Cards in this Set

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  • Back
What are the patterns of growth acceleration?
Prepubescence: limbs
Early adolescence: spine
Late adolescence: increased bone mineral deposition
Briefly describe the processing of vitamin D:
7-dehydrocholesterol + sun-> Vitamin D3->liver->25(OH)D->kidneys->1,25(OH)2D (most active form)
Does vitamin D increase or decrease calcium levels?
increase
Do PTH levels rise or lower in response to low calcium levels? What is the effect?
rise; this causes kidneys to increase production of active form of Vitamin D
What are the 4 categories of ricketts?
I-no calcium/vitamin D
II-no phosphate
III-resistance to vitamin D
IV-Ricketts-like diseases
Signs of ricketts?
bowed legs, curved bones, bony necklace, big joints, short stature, motor delays, CNS problems
If there is no response to vitamin D, is this likely to be classic ricketts?
no
What are things associated with vitamin D insufficiency?
preeclampsia; insufficient vitamin D in breast milk; inadequate bone mineralization; MS; cancers; TB
What is the adequate level of vitamin D?
30 ng/ml
How are RDA's for vitamin D established?
preventing recognized deficiencies, not on providing optimal amounts
T or F: humans can farm vitamin D from phytoplankton
true (fish have lots of vitamin D as a result)
Puncture through bare foot organism most commonly seen?
s. aureus
What is major concern in suppurative arthritis?
damage to physes
Who is primarily affected in suppurative arthritis?
children
What infection can be seen in suppurative arthritis in teens?
GC
In infants, you won't see swelling or redness in which joint in suppurative arthritis?
hip
Suppurative arthritis vs. osteomyelitis: which is joint? Which is bone?
suppurative is joint; osteomyelitis is bone
How is osteomyelitis spread?
hematogenously
What part of bones is most often affected in osteomyelitis?
diaphysis
Sickle cell associated with what bacteria?
salmonella
Treatment for osteomyelitis?
debride, drain, antibiotics, corticosteroids, and physical therapy
Triad of diskitis?
back pain, progressive loss of disk height, erosion of adjacent vertebral end-plates
What can differentiate between osteomyelitis and diskitis?
MRI
T or F: a clinical rickets syndrome that responds to administration of exogenous Vitamin D is by definition “classic” vitamin D deficient rickets
false
T or F: overlying inflammatory signs are usually appreciable early in the course of an osteomyelitis
false (insidious onset)
T or F: overlying inflammatory signs are usually appreciable early in the course of an osteoarthritis
true (except for hip)