Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
|
What bone tumors are found in the epiphysis?
|
Benign - giant cell tumor (osteoclastoma)
|
|
|
What bone tumors are found in the metaphysis?
|
Benign - osteochondroma; Malignant - osteosarcoma
|
|
|
What bone tumors are found in the diaphysis?
|
Benign - osteoid osteoma; Malignent - Ewing's sarcoma
|
|
|
What bone tumors are found in the intramedullary?
|
Benign - enchondroma; Malignant - chondrosarcoma
|
|
|
Disease: bone growing on bone, typically on the skull, associated with Gardner's syndrome (FAP)
|
Osteoma (benign)
|
|
|
Disease: <2 cm mass on proximal tibia and femur, typically men < 25 years of age, interlacting trabeculae of woven bone surrounded by osteoblasts
|
Osteoid osteoma (benign)
|
|
|
Disease: interlacing trabeculae of woven bone surrounded by osteoblasts, found in vertebral column
|
Osteoblastoma (benign)
|
|
|
Disease: occurs in epiphyseal ends on long bones, typically 20-40 yo, typically distal femur or proximal tibial region, 'soap bubble', spindle shaped cells with multinucleated giant cells
|
Giant cell tumor (benign)
|
|
|
Disease: long metaphysis, men < 25 yo, mature bone with cartinaginous cap
|
Osteochondroma - most common benign tumor; malignant transformation to chondrosarcoma is rare
|
|
|
Disease: cartilaginous neoplasm in intramedullary bone, usually distal extremities
|
Enchondroma (benign)
|
|
|
Disease: men 10-25 yo, metaphysis of long bones, typically around distal femur or proximal tibial region, Codman's triangle or sunburst pattern
|
Osteosarcoma (malignant); poor prognosis
|
|
|
What are the predisposing factors of osteosarcoma?
|
Paget's disease of bone, bone infarcts, radiation, familial retinoblastoma
|
|
|
Disease: small blue cell tumor, boys <15, extremely aggressive with early mets, but responds well to chemotherapy, onion-skin appearance, diaphysis of long bones pelvis scapula, and ribs
|
Ewing's sarcoma (malignant)
|
|
|
What is the genetics of Ewing's sarcoma?
|
11;22 translocation
|
|
|
Disease: cartilaginous tumor, men 30-60 yo, typically in pelvis, spine, humerus, tibia, or femur, expansile glistening mass within medullary cavity
|
Chondrosarcoma (malignant)
|
