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39 Cards in this Set

  • Front
  • Back
Cardinal signs of rheumatology
1. heat in joint
2. redness of joint
3. swelling
4. paint
5. loss of function
6. stiffness
11 S's of RA
1. synovitis
2. swelling
3. sex (F>M)
4. synovial effusions
5. stiffness
6. symmetry
7. serology
8. sed rate
9. subQ ndules at various joint junctions
10. systemic involvement
11. spinal involvement
psoriatic synovitis
erythema
soft tissue swelling
sausage digits
nail changes
-- not severe psoriasis, but very crippling
gout
hyperurecemia
podagra = foot/ankle
tophaceous = chronic
pustular synovitis
- infection of synovial space
- joint pain
- vesicles & pustules
- can spread to become bactermia & septicemia
- gonococcal dermatitis arthritis syndrome
septic olecranon bursitis
- not in joint; in bursa
- mosquito bite that is persistently scratched can be contaminated w/ Staphylococcus
- low glucose in joint fluid (due to bacT in bursa eating up sugar in joint fluid) indx bacT infection
- high sed rate indx of sev inflamm infxn
septic prepatellar bursitis
- inflamm of pre-patellar bursa
- needle placement during tap important
- wrong space = septic arthritis
synovitis of DJD
bony enlargement
Bouchard's nodes
Heberden's nodes
Bouchard's nodes
PIP
Heberden's nodes
DIP
sources of rheumatic symptoms
soft tissue disorders:
- outside joint
- bursitis/tendinitis
arthritis:
- w/in joint
- non-inflamm vs. inflamm
bone disorders:
- traumatic/ metabolic

** all 3 can co-exist (having one doesn't r/o the rest)
features of arthritis (characteristics)
inflammation, to varying degrees

all motion causes pain

pain generalized around joint

decreased ROM
inflamm vs/ non-inflamm arthritis
non-inflamm: OA
inflamm: RA, SLE, psoriatic arthritis
HPE for pts w/ arthritis
- duration of pain
- trauma
- possible sepsis
- rusty nail
- accident
- STDs
- ROS (diabetes, thyroid, fam hx)
clinical exam
examine:
- bursa
- tendon
- alignment
- symmetry
- fingers/palm (nodes, thumb opposition, fist formation)
- patella (fluid in bursa)
- ankle (alignment)
- synovitis
- calcaneous
- calcaneal bursa
- achilles bursa
- swelling
- gout
- OA
- metatarsa fracture
- stress fracture
- ROM
Acute phase reactants
- ESR
- C-RP (c-reactive protein)
- ESR = measures rate at which RBCs settle to bottom of test tube (inc mean inflammation; non-specific)
- C-RP = indicates tissue damage in body or severe inflamm
RF (rheumatoid factor)
85% of adults w/ RA have +RF
children w/ juvenile RA are -RF
ANA patterns of disease:
diseases a/w ANA
- SLE
- progressive systemic sclerosis
- Sjogren's syndrome
- Felty's syndrome
- Juvenile arthritis
nL sed rates in M and F
1. 0-50
2. 51-85
3. >85
0-50: M <15mm/h; F <20mm/h
51-85: M <20mm/h; F <30mm/h
>85: M <30mm/h; F <42mm/h
routine lab studies
CBC - different anemias point to different disorders; meds can cause anemia

Chemistries - CU GLUE
CPK, uric acid
Glucose, LFT, urinalysis, electrolytes
special arthritis tests
- complement levels
- CHLA testing
- ANCA
- cryoglobulins
- lyme titers
complement levels
- CH50; C3/C4
--if pt using up complement, they are being subjected to immune complexes
--pt has special Ab floating in blood
--these form complexes that deplete C3, C4, CH50
HLA testing
B27; D locus allelles

-- some types of HLA indx genetic predisposition to arthropathies
ANCA
dx of vasculitis
2 main types of dx procedures
- arthrocentesis
- arthroscopy
arthrocentesis
- in knee
- naked eye (looking for what)
- under patella at medial aspect
- determine turbidity, viscosity & color
blood in fluid (hemarthrosis) can indicate
- trauma
- bleedig disorders
- Willonodular synovitis
- pyrophosphate arthropathy
- charcot joint
- resolving infxn
- contaminated sample
classification of synovial effusions:
type; features; leukocytes
1. nL; clear/colorless/viscous; <200
2. non-inflamm; clear/yellow/viscous; 200-2,000
3. inflamm; cloudy/yellow/watery/low gluc; 2000-100000
***septic; purulent/v low gluc; >80000
types of synovial effusions:
group I
OA
early RA
trauma
osteochorditis dissecan
osteonecrosis
sickle cell
chronic/subsiding crystal synovitis
lupus
vasculitis
scleroderma
amylodosis
hypothyroidism
types of synovial effusions:
group II
RA
Reiter's
acute crystal synovitis
psoriatic arthritis
arthritis of IBD
ankylosing spondylitis
viral arthritis
rheumatic fever
juvenile chronic arthritis
behcat's syndrome
infection
types of synovial effusions:
group III
bacteria
fungal
mycobacterial
acute crystal synovitis
crystals found in synovial fluid:
1. monosodium urate monohydrate
2. calcium pyrophosphate dihydrate
3. basic calcium phosphate
4. calcium oxalate
5. lipid
6. cholesterol
1. acute/tophaceous gout; asymptomatic
2. acute pseudogout; destructive arthropathy; asymptomatic
3. acute calcific periarthritis; acute arthritis; destructive arthropathy
4. acute/subacute arthritis; asymptomatic
5. acute arthritis
6. asymptomatic
arthroscopy
- biospy must be done carefully
- ideal in most functional joints
key to diagnosis is clinical suspicion (ex of multiple systems involved)
- rash
- anemia
- thrombocytosis
- diastolic HTN
- testicular p
- ischemia
- proteinuria
symptoms and signs are varied and non-specific (ex of systemic)
- fevers
- malaise
- weight loss
symptoms per vessel size:
- large
- medium
- small
- pulseless, blindness, CVA, syncope
- CAD, renal atery, CVA, mononeuritis (wrist/foot drop)
- palpable purpura, Raynaud's/ gangrene
vasculitis classifications:
large
Takayasu
Temporal arteritis
vasculitis classifications:
medium
polyarteritis nodosa
vasculitis classifications:
small (also MC)
- churg-strauss syndrome
- wegener's granulomatosis
- Henoch-schonlein purpura
- hypersensitivity/ cutaneous vasculitis
- CVD associated vasculitis
- Goodpasture's syndrome
- Behcet disease