Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
21 Cards in this Set
- Front
- Back
|
MOA : penicillin, ampicillin, ticarcillin, pipercillin
bstatic or bcidal? |
Blocks cell wall synthesis by inhibition of peptidoglycan cross-linking
bcidal |
|
|
MOA : imipenem
bstatic or bcidal? |
Blocks cell wall synthesis by inhibition of peptidoglycan cross-linking
bcidal |
|
|
MOA : aztreonam
bstatic or bcidal? |
Blocks cell wall synthesis by inhibition of peptidoglycan cross-linking
Monobactam resistant to Beta-lactamase bcidal |
|
|
MOA : cephalosporins
bstatic or bcidal? |
Blocks cell wall synthesis by inhibition of peptidoglycan cross-linking
bcidal |
|
|
MOA : bacitracin
|
Blocks peptidoglycan synthesis (cell wall)
|
|
|
MOA : vancomycin
bstatic or bcidal? |
Blocks peptidoglycan synthesis
bcidal |
|
|
MOA : polymyxins
bstatic or bcidal? |
Disrupt bacterial cell wall membranes
bcidal |
|
|
MOA : Sulfonamides (SMX)
bstatic or bcidal? |
block nt synthesis
Competes with PABA. SMX inhibit dihydropteroate synthesase (enzyme that combines PABA + Pteridine into dihydropteroic acid) bcidal |
|
|
MOA : Trimethoprim (TMP)
bstatic or bcidal? |
block nt synthesis
by inhibiting dihydrofolate reductase (stops conversion of DHF to tetrahydrofolate--THF) bstatic |
|
|
MOA : Quinolones
bstatic or bcidal? |
Blocks DNA Topoisomerases
bcidal |
|
|
MOA : Rifampin
|
Blocks mRNA synthesis
TB drug used with isonazid 4 R's: 1) RNA polymerase inhibitor 2) Revs up microsomal P-450 3) Red/orange body fluids 4) Rapid resistance if used alone |
|
|
MOA : Chloramphenicol
bstatic or bcidal? |
Block protein synthesis @ 50 S Ribosomal subunit
bstatic |
|
|
MOA : Macrolides
bstatic or bcidal? |
Block protein synthesis @ 50 S Ribosomal subunit
bstatic |
|
|
MOA : Clindamycin
bstatic or bcidal? |
Block protein synthesis @ 50 S Ribosomal subunit
bstatic |
|
|
MOA : Streptogramins (quinupristin, dalfopristin)
|
Block protein synthesis @ 50 S Ribosomal subunit
|
|
|
MOA : Linezolid
bstatic or bcidal? |
Block protein synthesis @ 50 S Ribosomal subunit
bstatic or bcidal? -- VARIABLE |
|
|
MOA : Aminoglycosides
bstatic or bcidal? |
Block protein synthesis @ 30 S Ribosomal subunit
bcidal |
|
|
MOA : tetracyclines
bstatic or bcidal? |
Block protein synthesis @ 30 S Ribosomal subunit
bstatic |
|
|
What are macrolides?
bstatic or bcidal? |
Erythromycin
azithromycin (z-pack) clarithromycin bstatic |
|
|
What are aminoglycosides?
bstatic or bcidal? |
Gentamicin
Neomycin Amikacin Tobramycin Streptomycin bcidal |
|
|
MOA : metronidazole
bstatic or bcidal? |
(Anti-protozoal + Anaerobes)
Forms toxic metabolites in bacterial cell that damage DNA. bcidal |
