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61 Cards in this Set

  • Front
  • Back
what are the bacterial diseases that affect mice?
Pastereurellosis
mycoplasmosis
CAR bacillus
pseudomonas
murine colonic hyperplasia
salmonellosis
tyzzer's disease
staplococcal furunculosis
corynebacteriosis
What is the etiology of pasturellosis
pasteurella pneumotropica
how is pasterellosis transmitted
aerosol
fecal-oral
fomites (infected secretions)
what are the clinical signs of mouse pasteruellosis
None
conjunctivitis
panopthalmitis
torticollis
abscesses
mastitis
accesory sex glan abcesses
what is the pathology of pasterellosis
mucopurulent inflamation
necrosis
how can pasterellosis be diagnosed
culture
mixed infection
how is pasterellosis controlled
eliminate carriers within the colony i.e cagemeates and parents
what is the etiology of mouse mycoplasmosis
mycoplasma pulmonis
hos is mouse mycoplasmosis transmitted
aerosol
intrauterine
direct
what are the clinical signs of mycoplasmosis
none
oculonasal discharge
otitis media
labored breathing
anorexia
hunched posture
what is the gross pathology of mycoplasmosis
purulent discharge
*nasal mucosa
* tympanic bullae
bronchiectasis
red to gray consolidation
what is the histopathology of mycoplasmosis
purulent bronchopneumonia
BALT hyperplasia
how is mycoplasmosis diagnosed
mixed infections are common
M. pulmonis
P. pneumotropica
Sendai virus
Culture
ELISA
PCR
How is mycoplasmosis controlled
INtrauterine infections: cessarian derivation and embryo transfer

sanitation
avoid houseing mice and rats together
Transmission of CAR bacillus
direct contact
* first 2 wks from dam
* rabbits, rats, mystromys
clinical signs of CAR bacillus
none, alone
usually requires m. pulmonis,senda, pneumonia virus of mice
rales
wheezing
lethargy
weight loss
gross pathology of CAR bacillus
tracheitis
bronchitis
patchy lung consolidation
histopathology of CAR bacillus
BALT hyperplasia
mucosal hyperplasia
Warthin starry stain
Dx of CAR bacillus
histopath
ELISA
can't be cultured
control of car bacillus
sanitation
avoid housing rats and mice together
etiology of pseudomonas
pseudomonas aeruginosa
transmission of pseudomonas
ubiquitous
nonsterile water
clinical signs of pseudomonas
none
head tilt
SRS
death
* septicemia
* endotoxemia
gross pathology of pseudomonas
none

URT necrosis / ulceration
histopath of pseudomonas
spleen and liver
* vasculitis
* thrombosis
* necrosis
* hemorrhage
Dx of pseudomonas
culture
tissue gram stain
control of pseudomonas
acidification, chlorination, autoclaving, irradiate animals
Et of Murine colonic hyperplasia
citrobacter rodentium

Ddx: helicbacter spp.
clin signs of murine colonic hyperplasia
none in adults
suckling/weanlings
SRS
soft feces
rectal prolapse
mortality
gross path of murine colonic hyperplasia
thickened mucosa (descending colon / cecum)
histopath of murine colonic hyperplasia
elongated colonic crypts
silver stains
surface attatchement
little inflammation
cellular mitosis
dx of murine colonic hyperplasia
clin signs
histopath
culture
control of murine colonic hyperplasia
sanitation
reduce reproduction and introduction
Et of salmonellosis
S. typhimurium
S. enteridis
Clin signs of salmonellosis
none
acute death
SRS
Diarrhea
poor repro
gross path of salmonellosis
enlarged spleen
white to yello foci on liver
mucosal congestion / edema of sm int
mesentary throbosis of sm int
histopath of salmonellosis
multifocal hepatic and splenic necrosis
Dx of salmonellosis
decreased fecundity
gross lesions
feral mouse exposure
culture of liver, spleen , feces, mesenteric ln or ileum homogenates
control of salmonellosis
prevent vermin contamination
eliminate infected or exposed animals
is salmonellosis zoonotic
yes
et of tyzzer's disease
clostridium piliforme
transmission of tyzzers disease
fecal oral
clin signs of tyzzers disease
none: carrier state
SRS
Diarrhea
gross path of tyzzers disease
tyzzers triad
GI: illeium
hear
liver
histopath of tyzzers disease
giemsa stain
silver stains
PAS
Dx of tyzzers disease
gross
histopath
ELISA
PCR
ctrl of tyzzers disease
sanitaion i.e. autoclave, wash, disinfect
et. of staphylococcal furunculosis
s. aureus
s. epidermidis
transmission of staphylococcal furunculosis
direct contact
fomites
clinical signs of staphylococcal furunculosis
cutaneous infections
* hypergroomin
* fight wounds
conjunctivitis
gross path of staphylococcal furunculosis
lumps and bumps
esp on face and head
histopath of staphylococcal furunculosis
granuloma with bacterial core surrounded by neutrophils, macs and fibrocytes
Dx of staphylococcal furunculosis
clin signs
culture
control of staph furunculosis
sanitation
et of corynebacteriosis
corynebacterium kutscheri
c. bovis (nude mice / skin)
c. hoffmani (conjunctivitis)
trans of corynebacteriosis
direct contact with feces
clin signs of corynebacteriosis
none
SRS
oculonasal discahrge
SQ abscesses
septic swollen joints
gangrene amputations of extremities
gross path of corynebacteriosis
focal necrosis and abscesses in highly vascular organs / joint involvment
histopath of corynebacteriosis
gram stained
chinese letters
dx of corynebacteriosis
gross path
histopath
culture
elisa
control of corynebacteriosis
id subclinically infected animals
eliminate
avoid houseing mice / rats together
good sanitation