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61 Cards in this Set
- Front
- Back
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what are the bacterial diseases that affect mice?
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Pastereurellosis
mycoplasmosis CAR bacillus pseudomonas murine colonic hyperplasia salmonellosis tyzzer's disease staplococcal furunculosis corynebacteriosis |
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What is the etiology of pasturellosis
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pasteurella pneumotropica
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how is pasterellosis transmitted
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aerosol
fecal-oral fomites (infected secretions) |
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what are the clinical signs of mouse pasteruellosis
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None
conjunctivitis panopthalmitis torticollis abscesses mastitis accesory sex glan abcesses |
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what is the pathology of pasterellosis
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mucopurulent inflamation
necrosis |
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how can pasterellosis be diagnosed
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culture
mixed infection |
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how is pasterellosis controlled
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eliminate carriers within the colony i.e cagemeates and parents
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what is the etiology of mouse mycoplasmosis
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mycoplasma pulmonis
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hos is mouse mycoplasmosis transmitted
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aerosol
intrauterine direct |
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what are the clinical signs of mycoplasmosis
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none
oculonasal discharge otitis media labored breathing anorexia hunched posture |
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what is the gross pathology of mycoplasmosis
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purulent discharge
*nasal mucosa * tympanic bullae bronchiectasis red to gray consolidation |
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what is the histopathology of mycoplasmosis
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purulent bronchopneumonia
BALT hyperplasia |
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how is mycoplasmosis diagnosed
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mixed infections are common
M. pulmonis P. pneumotropica Sendai virus Culture ELISA PCR |
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How is mycoplasmosis controlled
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INtrauterine infections: cessarian derivation and embryo transfer
sanitation avoid houseing mice and rats together |
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Transmission of CAR bacillus
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direct contact
* first 2 wks from dam * rabbits, rats, mystromys |
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clinical signs of CAR bacillus
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none, alone
usually requires m. pulmonis,senda, pneumonia virus of mice rales wheezing lethargy weight loss |
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gross pathology of CAR bacillus
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tracheitis
bronchitis patchy lung consolidation |
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histopathology of CAR bacillus
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BALT hyperplasia
mucosal hyperplasia Warthin starry stain |
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Dx of CAR bacillus
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histopath
ELISA can't be cultured |
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control of car bacillus
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sanitation
avoid housing rats and mice together |
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etiology of pseudomonas
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pseudomonas aeruginosa
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transmission of pseudomonas
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ubiquitous
nonsterile water |
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clinical signs of pseudomonas
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none
head tilt SRS death * septicemia * endotoxemia |
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gross pathology of pseudomonas
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none
URT necrosis / ulceration |
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histopath of pseudomonas
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spleen and liver
* vasculitis * thrombosis * necrosis * hemorrhage |
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Dx of pseudomonas
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culture
tissue gram stain |
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control of pseudomonas
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acidification, chlorination, autoclaving, irradiate animals
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Et of Murine colonic hyperplasia
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citrobacter rodentium
Ddx: helicbacter spp. |
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clin signs of murine colonic hyperplasia
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none in adults
suckling/weanlings SRS soft feces rectal prolapse mortality |
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gross path of murine colonic hyperplasia
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thickened mucosa (descending colon / cecum)
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histopath of murine colonic hyperplasia
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elongated colonic crypts
silver stains surface attatchement little inflammation cellular mitosis |
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dx of murine colonic hyperplasia
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clin signs
histopath culture |
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control of murine colonic hyperplasia
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sanitation
reduce reproduction and introduction |
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Et of salmonellosis
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S. typhimurium
S. enteridis |
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Clin signs of salmonellosis
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none
acute death SRS Diarrhea poor repro |
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gross path of salmonellosis
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enlarged spleen
white to yello foci on liver mucosal congestion / edema of sm int mesentary throbosis of sm int |
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histopath of salmonellosis
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multifocal hepatic and splenic necrosis
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Dx of salmonellosis
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decreased fecundity
gross lesions feral mouse exposure culture of liver, spleen , feces, mesenteric ln or ileum homogenates |
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control of salmonellosis
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prevent vermin contamination
eliminate infected or exposed animals |
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is salmonellosis zoonotic
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yes
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et of tyzzer's disease
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clostridium piliforme
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transmission of tyzzers disease
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fecal oral
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clin signs of tyzzers disease
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none: carrier state
SRS Diarrhea |
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gross path of tyzzers disease
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tyzzers triad
GI: illeium hear liver |
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histopath of tyzzers disease
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giemsa stain
silver stains PAS |
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Dx of tyzzers disease
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gross
histopath ELISA PCR |
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ctrl of tyzzers disease
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sanitaion i.e. autoclave, wash, disinfect
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et. of staphylococcal furunculosis
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s. aureus
s. epidermidis |
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transmission of staphylococcal furunculosis
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direct contact
fomites |
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clinical signs of staphylococcal furunculosis
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cutaneous infections
* hypergroomin * fight wounds conjunctivitis |
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gross path of staphylococcal furunculosis
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lumps and bumps
esp on face and head |
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histopath of staphylococcal furunculosis
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granuloma with bacterial core surrounded by neutrophils, macs and fibrocytes
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Dx of staphylococcal furunculosis
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clin signs
culture |
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control of staph furunculosis
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sanitation
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et of corynebacteriosis
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corynebacterium kutscheri
c. bovis (nude mice / skin) c. hoffmani (conjunctivitis) |
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trans of corynebacteriosis
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direct contact with feces
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clin signs of corynebacteriosis
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none
SRS oculonasal discahrge SQ abscesses septic swollen joints gangrene amputations of extremities |
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gross path of corynebacteriosis
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focal necrosis and abscesses in highly vascular organs / joint involvment
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histopath of corynebacteriosis
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gram stained
chinese letters |
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dx of corynebacteriosis
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gross path
histopath culture elisa |
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control of corynebacteriosis
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id subclinically infected animals
eliminate avoid houseing mice / rats together good sanitation |
