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128 Cards in this Set
- Front
- Back
What are 3 non-lesions of the esophagus?
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Hyperkeratosis
Muscular hypertrophy of the distal esophagus (horse) Esophageal food bolus (rule out choke) |
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How do you distinguish an agonal food bolus from choke?
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Look for mucosal reaction – hyperemic response with choke
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The esophagus heals by ____________, not by ___________.
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Heals by scarring/ fibrosis
Not by regeneration |
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The esophagus heals poorly, with fibrosis leading to ________________.
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Stenosis
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What are 2 causes of corrosive esophagitis?
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Ingestion of irritating substances
Regurgitation of gastric contents |
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What parasite leaves little tracts in the esophagus of ruminants?
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Gonglyonema
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What is the name of the nematode parasite of dogs that forms nodules in the wall of the esophagus?
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Spirocerca lupi
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What can happen if these nodules are allowed to progress?
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They can transform into mesenchymal neoplasms like fibrosarcoma and osteosarcoma
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What parasite is very common in the esophageal musculature of ruminants?
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Sarcosporidia
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What kinds of tumors can be seen in the esophagus?
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Papillomas occasionally in cattle, dogs, and cats
SCC and mesenchymal tumors rarely |
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Which form of bloat is typically secondary to esophageal obstruction?
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Acute or Free gas bloat
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How do you distinguish free gas bloat from post-mortem rumen distension?
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Postmortem distension has no obvious obstruction, might see bloat line with free gas bloat
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What type of bloat tends to be seen in herd outbreaks?
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Frothy bloat
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How does bloat kill an animal?
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Increases abdominal/thoracic pressure and impedes venous return –die of hypovolemic shock
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What is a bloat line?
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The esophageal mucosa proximal to the thoracic inlet is hyperemic whereas that in the thoracic esophagus is blanched. The bloat line is the margin of these two areas.
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What is the first event that occurs in canine bloat?
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Gastric dilation
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What are some characteristics of lactic acidosis?
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Low rumen pH
Degeneration and necrosis of rumen epithelium Rumenal vesicles Invasion of bacteria and fungi into rumen wall High grain diet |
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What lesions are typically seen with lactic acidosis?
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Vesicles/ ulcers in rumen with necrosis of tissue
Liver abscesses |
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What is the name of the disease in which sharp objects swallowed by cattle penetrate the wall of the reticulum and cause peritonitis?
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Traumatic reticuloperitonitis or “Hardware disease”
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What lesions would you see with hardware disease?
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Fibrinous or fibrinopurulent peritonitis
Possibly pleuritis or pericarditis |
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What is a trichobezoar?
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A hairball
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Carnivores lack what region of the stomach?
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The aglandular part
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Which compartment is the true stomach of the ruminant?
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The abomasum
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What do goblet cells secrete?
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Mucin
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What do chief cells secrete?
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Pepsinogen
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What do parietal cells secrete?
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HCl
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What do the endocrine cells secrete?
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A variety of amine and peptide hormones such as gastrin
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What are 3 non-lesions of the stomach?
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Physiologic hyperemia
Postmortem gastric rupture in calves and horses Torus pyloricus |
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What is torus pyloricus?
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A tongue-shaped bulge at the gastroduodenal junction especially prominent in pigs and goats
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What 2 types of abomasal displacement are there? Which has a better prognosis?
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Simple/ uncomplicated usually seen in dairy cattle has a better prognosis – organ displaced to left or right of normal position
Volvulus – abomasum twists on its mesentery and occludes venous drainage – poor prognosis (rapid death) – usually seen in calves |
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In what 2 species is gastric dilatation especially common and important?
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Dog and Horse
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Ruminal papilloma virus + _____?______ (plant) -> cancer
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Brackenfern
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How can you distinguish antemortum gastric rupture from postmortem gastric rupture?
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Look for signs of hemorrhage and inflammation
Peritonitis, hyperemia, hemorrhage at the margins of the tear, fibrin deposition |
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In the glandular stomach, there are 2 major distributions of ulcers seen – what are they?
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Multiple superficial ulcers
Single or several large craterous ulcers |
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What are 6 potential causes of multifocal superficial ulcers?
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Uremia
Viruses Toxins Septicemia Gastritis Parasites |
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What are some etiologies of large craterous ulcers?
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Idiopathic
Neoplasia Foreign body |
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What are some potential consequences of gastric ulcers?
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Hemorrhage (melena, anemia, etc)
Perforation (peritonitis) Colonization of bacteria (i.e. Clostridium botulinum type B in horses) |
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What kind of epithelium covers the aglandular portion of the stomach in pigs and horses?
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Stratified squamous epithelium
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Which species will slough its squamous gastric epithelium?
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Pigs
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True or false: Ulceration of the squamous portion of the pig stomach is very common and important.
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True
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What can idiopathic ulceration of the squamous portion of the pig stomach lead to? (2 important consequences)
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Hemorrhage
Exsanguination |
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Training racehorses tend to get what kind of ulcers? What part(s) of the stomach does it affect?
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Stress ulcers
Both glandular and aglandular regions |
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What kind of ulcers do sled dogs in Alaska tend to get?
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Stress ulcers
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What is the signalment of horses that typically get squamous gastric ulcers?
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Stressed foals under 4 months
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Ulcers of the pars esophagea of foals have been associated with what 3 conditions?
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Gastric reflux
Gastrophilus infestation Candida infection |
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Aspirin causes ulceration of the glandular stomach in which species?
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Cats and dogs
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Phenylbutazone cuases ulcerations of the glandular stomach in which species?
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Dog and horse
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What class of drugs reduces blood flow to the mucosa?
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NSAIDs
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What viruses may be associated with gastric ulcers?
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BVD
MCF FMD Bluetongue Papular stomatitis IBR Rinderpest |
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Ingestion of blister beetles causes gastric ulceration in what species?
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Horses
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Why would a dog with a mast cell tumor get gastric ulcers?
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Mast cells secrete histamine, a major stimulator of gastric acid secretion
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Tumors of the delta cells of the pancreatic islets may produce excess ___________ that may result in gastric ulcers.
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Gastrin
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Acute gastritis is characterized by what type of exudate?
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Hemorrhagic exudates
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Hemorrhagic exudate is indistinguishable from what?
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Gastric hemorrhage (without inflammation)
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What are some important causes of acute gastritis in dogs?
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DIC
Parvovirus Distemper Bacterial gastritis (garbage can gastritis) All the things that cause ulcers |
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What are some causes of gastritis in species other than the dog?
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Same things that cause ulcers
(FB, uremia, viruses, toxins, septicemia, parasites, neoplasia, etc) |
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Braxy is a disease characterized by discrete areas of hemorrhagic necrosis in the stomach of ruminants that is caused by _______________.
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Clostridial infections
(Cl. septicum) |
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_______________ is a blood sucking parasite in the abomasum of small ruminants and will rapidly cause death from blood loss.
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Haemonchus
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What are 2 forms of chronic gastritis?
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Gastric abscess
Lymphocytic/ plasmacytic gastritis |
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Gastric abscesses are usually bacterial except for those induced by _________ in horses.
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Draschia
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Lymphocytic/ plasmacytic gastritis is associated with ____________ in herbivores.
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Parasitism
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Lymphocytic/ plasmacytic gastritis in cats is associated with ______________ infection.
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Helicobacter pylori
Helicobacter felis |
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Lymphocytic/ plasmacytic gastritis and related eosinophilic gastritis in dogs is likely to be related to what?
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Abnormal stimulation of the immune system by antigens in the food
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Gastric mucosal hypertrophy is significant because it leads to what?
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Protein-losing gastropathy
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Type I ostertagiasis in cattle causes what gastric reaction?
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Acute hemorrhagic gastritis
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Type II ostertagiasis in cattle causes what gastric reaction?
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Hyperplasia
Metaplasia (loss of parietal cells) Mucosal hypertrophy (focal or diffuse) |
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Mucosal hypertrophy with resultant cobblestone appearance to the glandular portion of the equine stomach has been attributed to ____________ infection.
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Trichostrongyle
(Trichostrongylus axei) |
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In what two dog breeds is gastric mucosal hypertrophy especially common? What disease do they typically already have?
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Basenji and Boxer
Lymphocytic/ plasmacytic gastroeneritis |
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How do adenomatous polyps of the canine stomach cause disease?
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Block pyloric outflow
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What breeds typically get adenomatous polyps?
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Small breeds
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You find a large ulcerated cauliflower like lesion in the stomach with a sterile peritonitis. What is the probable diagnosis?
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Gastric carcinoma
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Where do gastric carcinomas occur in the canine stomach?
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Pyloric region
Can cause pyloric stenosis |
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Where do gastric carcinomas occur in the equine stomach?
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Aglandular portion
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True or false: Gastric carcinomas tend to be ulcerated.
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True
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In which species are gastric leiomyomas and leiomyosarcomas most common?
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Dog
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What do leiomyo(sarco)mas look like grossly?
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Nodular lesions +/-ulceration of overlying mucosa
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Gastric lymphosarcoma (lymphoma) is common in cattle with the multicentric form of ____________.
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Bovine leukosis
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What does gastric lymphoma in cattle look like grossly?
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Thickening of abomasal wall with homogenous soft cream color
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What does gastric lymphoma look like in cats, dogs, and horses?
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EITHER diffuse infiltration of mucosa
OR Discrete nodules or plaques of tumor |
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True or false: Blood-staining of ingesta at necropsy is an indication of hemorrhage into the intestinal tract.
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False.
Blood leaks out into the gut lumen after death and stains the ingesta. |
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True or false: Hyperemia of the intestinal tract likely indicates inflammation.
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False.
May be physiologic hyperemia |
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What is terminal intussusception caused by?
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Irregular peristalsis that continues after death
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What is hemamelasma ilei and what is its significance?
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Red-brown plaques on the serosal surface of the horse ileum.
Incidental finding – no known pathology |
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Hirshsprungs disease or intestinal agangliosis tends to occur in what color and breed of horse?
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White (overo) American Paint
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What are 4 types of changes intestinal in position?
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Hernia
Volvulus Intussusception Displacement |
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What are the potential consequences of changes in intestinal position?
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Incarceration of affected bowel
(ischemic bowel disease) |
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Name a cause of intestinal strangulation in the horse that involves a benign tumor.
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Pedunculated lipoma
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The twisting of a loop of bowel about its mesenteric base of attachment is termed what?
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Volvulus
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The telescoping of one segment of gut inside another is termed what?
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Intussusception
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Displacements and torsions are especially common in the colon of which species?
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Equine
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Left dorsal displacement of the equine colon is also called what?
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Nephrosplenic entrapment
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What is the causative agent of verminous arteritis?
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Strongyle migration
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What does verminous arteritis do to the intestine?
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Thrombosis of mesenteric blood vessels
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What does infarcted bowel look like grossly?
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Dark red and edematous,congested transmurally, sharply demarcated from normal bowel, and wall rapidly undergoes necrosis and becomes friable.
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What are some causes of intestinal obstruction?
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Congenital anomalies
Bowel displacement Foreign bodies Scarring or external compression from a mass Parasites, enteroliths, etc |
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What are some consequences of intestinal obstruction?
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Rupture
Ulceration |
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Define typhlitis.
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Inflammation of the caecum
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Define proctitis.
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Inflammation of the rectum
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What are some causes of hemorrhagic enteritis?
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Viral
Bacterial Toxins Parasites DIC in dogs Fungus Uremia |
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What are some viral causes of hemorrhagic enteritis?
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Canine parvo (not feline)
Canine coronavirus BVD (mucosal disease) Hog Cholera ASF Winter dysentery of cattle (corona or bredavirus) |
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What bacteria can cause hemorrhagic enteritis?
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Salmonella in ruminants, horses, swine
EPEC (O157) Clostridium perfringens A,B, C in large animals Clostridium difficile Rhodococcus equi Erlichia risticii (Potomac Horse Fever) Brachyspira hyodysenteriae (swine dysentery) Lawsonia Clostridium piliformis Neorickettsia helminthoeca |
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What toxins can cause hemorrhagic enteritis?
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NSAIDs
Blister beetle in horses Oakbud in horses |
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What parasites can cause hemorrhagic enteritis?
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Truchuris (whipworms)
Coccidiosis – cattle, pigs, dogs especially Ancylostoma, Bunostomum |
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Which agents cause fibrinous enteritis?
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Salmonella
Coccidosis Tyzzer’s disease |
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What does the mucosa of the intestine look like with granulomatous enteritis?
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Thickened and thrown into broad folds
Bowel edematous Lymphangiectasia may occur |
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Histiocytic colitis in boxers is associated with what pathogen?
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E. coli
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What are 2 clinical signs you might see in an animal with chronic granulomatous enteritis?
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Chronic diarrhea
Hypoproteinemia (secondary to protein losing enteropathy) |
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What is the causative agent of Johne’s disease?
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Mycobacterium paratuberculosis
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Which part of the gut is most commonly affected in Johne’s disease?
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Distal ileum
Less commonly proximal large bowel |
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Which lymph nodes are affected in Johne’s disease?
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The ones adjacent to the bowel. Maybe they are mesenteric…
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Equine granulomatous enteritis is most commonly seen in which breed of horse?
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Standarbred
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What is the causative agent of equine granulomatous enteritis?
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Mycobacterium avium
Some cases we don’t know what causes it |
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Granulomatous enteritis may be encountered with specific agents such as ___________ in dogs and ____________ in foals.
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Histoplasma
Rhodococcus equi |
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Lymphocytic/ plasmacytic gastritis/enteritis/ colitis occurs in dogs and cats in response to what?
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Hypersensitivity response to ingested dietary allergens
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Lymphocytic/ plasmacytic gastritis/enteritis/ colitis is also a familial disease in some breeds such as the ___________.
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Basenji
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Lymphocytic/ plasmacytic gastritis/enteritis/ colitis is sometimes associated with specific agents such as _______________ and __________________.
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Giardia
Trichomonas |
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Chronic eosinophilic gastritis/ enteritis/ colitis is associated with __________________.
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Intestinal parasitic infections.
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In intestinal lymphangiectasia, what will rupture of dilated lymphatics produce in the mesentery and serosal surface of the affected bowel?
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Granulomas
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True or false: Polyps of the canine rectum or colon are not uncommon.
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True
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Intestinal carcinomas are relatively uncommon except in ___________ (species) in certain areas of the world.
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Sheep
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Intestinal carcinomas are typically annular lesions which may cause ___________ of the bowel lumen.
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Stenosis
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Which of the following is FALSE about intestinal carcinomas?
a. Uncommon except in sheep in some areas of the world b. Can affect any area of the small or large intestine c. Typically annular lesion that can causes stenosis of the bowel lumen d. Mucosal surface often ulcerated e. Locally aggressive lesion, but rarely metastasizes |
E – may metastasize widely
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What cells are the endocrine tumors of the intestine derived from?
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Enterochromaffin or Kulschitsky cells
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Intestinal lymphoma is seen especially in which species?
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Cats
Dogs Horses |
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What does intestinal lymphoma look like?
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Whatever it wants to look like
Nodules of tumor Diffuse infiltrates May look grossly and histologically like chronic enteritis and has similar clinical signs |
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Perianal gland tumors from the perianal hepatoid glands are typically (benign/ malignant).
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Benign
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Which perianal gland tumors are invariably malignant?
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Apocrine glands of anal sac
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Intestinal mast cell tumor, though rare, occurs in which species?
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Dog and cat
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