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128 Cards in this Set

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  • Back
What are 3 non-lesions of the esophagus?
Hyperkeratosis
Muscular hypertrophy of the distal esophagus (horse)
Esophageal food bolus (rule out choke)
How do you distinguish an agonal food bolus from choke?
Look for mucosal reaction – hyperemic response with choke
The esophagus heals by ____________, not by ___________.
Heals by scarring/ fibrosis
Not by regeneration
The esophagus heals poorly, with fibrosis leading to ________________.
Stenosis
What are 2 causes of corrosive esophagitis?
Ingestion of irritating substances
Regurgitation of gastric contents
What parasite leaves little tracts in the esophagus of ruminants?
Gonglyonema
What is the name of the nematode parasite of dogs that forms nodules in the wall of the esophagus?
Spirocerca lupi
What can happen if these nodules are allowed to progress?
They can transform into mesenchymal neoplasms like fibrosarcoma and osteosarcoma
What parasite is very common in the esophageal musculature of ruminants?
Sarcosporidia
What kinds of tumors can be seen in the esophagus?
Papillomas occasionally in cattle, dogs, and cats
SCC and mesenchymal tumors rarely
Which form of bloat is typically secondary to esophageal obstruction?
Acute or Free gas bloat
How do you distinguish free gas bloat from post-mortem rumen distension?
Postmortem distension has no obvious obstruction, might see bloat line with free gas bloat
What type of bloat tends to be seen in herd outbreaks?
Frothy bloat
How does bloat kill an animal?
Increases abdominal/thoracic pressure and impedes venous return –die of hypovolemic shock
What is a bloat line?
The esophageal mucosa proximal to the thoracic inlet is hyperemic whereas that in the thoracic esophagus is blanched. The bloat line is the margin of these two areas.
What is the first event that occurs in canine bloat?
Gastric dilation
What are some characteristics of lactic acidosis?
Low rumen pH
Degeneration and necrosis of rumen epithelium
Rumenal vesicles
Invasion of bacteria and fungi into rumen wall
High grain diet
What lesions are typically seen with lactic acidosis?
Vesicles/ ulcers in rumen with necrosis of tissue
Liver abscesses
What is the name of the disease in which sharp objects swallowed by cattle penetrate the wall of the reticulum and cause peritonitis?
Traumatic reticuloperitonitis or “Hardware disease”
What lesions would you see with hardware disease?
Fibrinous or fibrinopurulent peritonitis
Possibly pleuritis or pericarditis
What is a trichobezoar?
A hairball
Carnivores lack what region of the stomach?
The aglandular part
Which compartment is the true stomach of the ruminant?
The abomasum
What do goblet cells secrete?
Mucin
What do chief cells secrete?
Pepsinogen
What do parietal cells secrete?
HCl
What do the endocrine cells secrete?
A variety of amine and peptide hormones such as gastrin
What are 3 non-lesions of the stomach?
Physiologic hyperemia
Postmortem gastric rupture in calves and horses
Torus pyloricus
What is torus pyloricus?
A tongue-shaped bulge at the gastroduodenal junction especially prominent in pigs and goats
What 2 types of abomasal displacement are there? Which has a better prognosis?
Simple/ uncomplicated usually seen in dairy cattle has a better prognosis – organ displaced to left or right of normal position
Volvulus – abomasum twists on its mesentery and occludes venous drainage – poor prognosis (rapid death) – usually seen in calves
In what 2 species is gastric dilatation especially common and important?
Dog and Horse
Ruminal papilloma virus + _____?______ (plant) -> cancer
Brackenfern
How can you distinguish antemortum gastric rupture from postmortem gastric rupture?
Look for signs of hemorrhage and inflammation
Peritonitis, hyperemia, hemorrhage at the margins of the tear, fibrin deposition
In the glandular stomach, there are 2 major distributions of ulcers seen – what are they?
Multiple superficial ulcers
Single or several large craterous ulcers
What are 6 potential causes of multifocal superficial ulcers?
Uremia
Viruses
Toxins
Septicemia
Gastritis
Parasites
What are some etiologies of large craterous ulcers?
Idiopathic
Neoplasia
Foreign body
What are some potential consequences of gastric ulcers?
Hemorrhage (melena, anemia, etc)
Perforation (peritonitis)
Colonization of bacteria (i.e. Clostridium botulinum type B in horses)
What kind of epithelium covers the aglandular portion of the stomach in pigs and horses?
Stratified squamous epithelium
Which species will slough its squamous gastric epithelium?
Pigs
True or false: Ulceration of the squamous portion of the pig stomach is very common and important.
True
What can idiopathic ulceration of the squamous portion of the pig stomach lead to? (2 important consequences)
Hemorrhage
Exsanguination
Training racehorses tend to get what kind of ulcers? What part(s) of the stomach does it affect?
Stress ulcers
Both glandular and aglandular regions
What kind of ulcers do sled dogs in Alaska tend to get?
Stress ulcers
What is the signalment of horses that typically get squamous gastric ulcers?
Stressed foals under 4 months
Ulcers of the pars esophagea of foals have been associated with what 3 conditions?
Gastric reflux
Gastrophilus infestation
Candida infection
Aspirin causes ulceration of the glandular stomach in which species?
Cats and dogs
Phenylbutazone cuases ulcerations of the glandular stomach in which species?
Dog and horse
What class of drugs reduces blood flow to the mucosa?
NSAIDs
What viruses may be associated with gastric ulcers?
BVD
MCF
FMD
Bluetongue
Papular stomatitis
IBR
Rinderpest
Ingestion of blister beetles causes gastric ulceration in what species?
Horses
Why would a dog with a mast cell tumor get gastric ulcers?
Mast cells secrete histamine, a major stimulator of gastric acid secretion
Tumors of the delta cells of the pancreatic islets may produce excess ___________ that may result in gastric ulcers.
Gastrin
Acute gastritis is characterized by what type of exudate?
Hemorrhagic exudates
Hemorrhagic exudate is indistinguishable from what?
Gastric hemorrhage (without inflammation)
What are some important causes of acute gastritis in dogs?
DIC
Parvovirus
Distemper
Bacterial gastritis (garbage can gastritis)
All the things that cause ulcers
What are some causes of gastritis in species other than the dog?
Same things that cause ulcers
(FB, uremia, viruses, toxins, septicemia, parasites, neoplasia, etc)
Braxy is a disease characterized by discrete areas of hemorrhagic necrosis in the stomach of ruminants that is caused by _______________.
Clostridial infections
(Cl. septicum)
_______________ is a blood sucking parasite in the abomasum of small ruminants and will rapidly cause death from blood loss.
Haemonchus
What are 2 forms of chronic gastritis?
Gastric abscess
Lymphocytic/ plasmacytic gastritis
Gastric abscesses are usually bacterial except for those induced by _________ in horses.
Draschia
Lymphocytic/ plasmacytic gastritis is associated with ____________ in herbivores.
Parasitism
Lymphocytic/ plasmacytic gastritis in cats is associated with ______________ infection.
Helicobacter pylori
Helicobacter felis
Lymphocytic/ plasmacytic gastritis and related eosinophilic gastritis in dogs is likely to be related to what?
Abnormal stimulation of the immune system by antigens in the food
Gastric mucosal hypertrophy is significant because it leads to what?
Protein-losing gastropathy
Type I ostertagiasis in cattle causes what gastric reaction?
Acute hemorrhagic gastritis
Type II ostertagiasis in cattle causes what gastric reaction?
Hyperplasia
Metaplasia (loss of parietal cells)
Mucosal hypertrophy (focal or diffuse)
Mucosal hypertrophy with resultant cobblestone appearance to the glandular portion of the equine stomach has been attributed to ____________ infection.
Trichostrongyle
(Trichostrongylus axei)
In what two dog breeds is gastric mucosal hypertrophy especially common? What disease do they typically already have?
Basenji and Boxer
Lymphocytic/ plasmacytic gastroeneritis
How do adenomatous polyps of the canine stomach cause disease?
Block pyloric outflow
What breeds typically get adenomatous polyps?
Small breeds
You find a large ulcerated cauliflower like lesion in the stomach with a sterile peritonitis. What is the probable diagnosis?
Gastric carcinoma
Where do gastric carcinomas occur in the canine stomach?
Pyloric region
Can cause pyloric stenosis
Where do gastric carcinomas occur in the equine stomach?
Aglandular portion
True or false: Gastric carcinomas tend to be ulcerated.
True
In which species are gastric leiomyomas and leiomyosarcomas most common?
Dog
What do leiomyo(sarco)mas look like grossly?
Nodular lesions +/-ulceration of overlying mucosa
Gastric lymphosarcoma (lymphoma) is common in cattle with the multicentric form of ____________.
Bovine leukosis
What does gastric lymphoma in cattle look like grossly?
Thickening of abomasal wall with homogenous soft cream color
What does gastric lymphoma look like in cats, dogs, and horses?
EITHER diffuse infiltration of mucosa
OR
Discrete nodules or plaques of tumor
True or false: Blood-staining of ingesta at necropsy is an indication of hemorrhage into the intestinal tract.
False.
Blood leaks out into the gut lumen after death and stains the ingesta.
True or false: Hyperemia of the intestinal tract likely indicates inflammation.
False.
May be physiologic hyperemia
What is terminal intussusception caused by?
Irregular peristalsis that continues after death
What is hemamelasma ilei and what is its significance?
Red-brown plaques on the serosal surface of the horse ileum.
Incidental finding – no known pathology
Hirshsprungs disease or intestinal agangliosis tends to occur in what color and breed of horse?
White (overo) American Paint
What are 4 types of changes intestinal in position?
Hernia
Volvulus
Intussusception
Displacement
What are the potential consequences of changes in intestinal position?
Incarceration of affected bowel
(ischemic bowel disease)
Name a cause of intestinal strangulation in the horse that involves a benign tumor.
Pedunculated lipoma
The twisting of a loop of bowel about its mesenteric base of attachment is termed what?
Volvulus
The telescoping of one segment of gut inside another is termed what?
Intussusception
Displacements and torsions are especially common in the colon of which species?
Equine
Left dorsal displacement of the equine colon is also called what?
Nephrosplenic entrapment
What is the causative agent of verminous arteritis?
Strongyle migration
What does verminous arteritis do to the intestine?
Thrombosis of mesenteric blood vessels
What does infarcted bowel look like grossly?
Dark red and edematous,congested transmurally, sharply demarcated from normal bowel, and wall rapidly undergoes necrosis and becomes friable.
What are some causes of intestinal obstruction?
Congenital anomalies
Bowel displacement
Foreign bodies
Scarring or external compression from a mass
Parasites, enteroliths, etc
What are some consequences of intestinal obstruction?
Rupture
Ulceration
Define typhlitis.
Inflammation of the caecum
Define proctitis.
Inflammation of the rectum
What are some causes of hemorrhagic enteritis?
Viral
Bacterial
Toxins
Parasites
DIC in dogs
Fungus
Uremia
What are some viral causes of hemorrhagic enteritis?
Canine parvo (not feline)
Canine coronavirus
BVD (mucosal disease)
Hog Cholera
ASF
Winter dysentery of cattle (corona or bredavirus)
What bacteria can cause hemorrhagic enteritis?
Salmonella in ruminants, horses, swine
EPEC (O157)
Clostridium perfringens A,B, C in large animals
Clostridium difficile
Rhodococcus equi
Erlichia risticii (Potomac Horse Fever)
Brachyspira hyodysenteriae (swine dysentery)
Lawsonia
Clostridium piliformis
Neorickettsia helminthoeca
What toxins can cause hemorrhagic enteritis?
NSAIDs
Blister beetle in horses
Oakbud in horses
What parasites can cause hemorrhagic enteritis?
Truchuris (whipworms)
Coccidiosis – cattle, pigs, dogs especially
Ancylostoma, Bunostomum
Which agents cause fibrinous enteritis?
Salmonella
Coccidosis
Tyzzer’s disease
What does the mucosa of the intestine look like with granulomatous enteritis?
Thickened and thrown into broad folds
Bowel edematous
Lymphangiectasia may occur
Histiocytic colitis in boxers is associated with what pathogen?
E. coli
What are 2 clinical signs you might see in an animal with chronic granulomatous enteritis?
Chronic diarrhea
Hypoproteinemia (secondary to protein losing enteropathy)
What is the causative agent of Johne’s disease?
Mycobacterium paratuberculosis
Which part of the gut is most commonly affected in Johne’s disease?
Distal ileum
Less commonly proximal large bowel
Which lymph nodes are affected in Johne’s disease?
The ones adjacent to the bowel. Maybe they are mesenteric…
Equine granulomatous enteritis is most commonly seen in which breed of horse?
Standarbred
What is the causative agent of equine granulomatous enteritis?
Mycobacterium avium
Some cases we don’t know what causes it
Granulomatous enteritis may be encountered with specific agents such as ___________ in dogs and ____________ in foals.
Histoplasma
Rhodococcus equi
Lymphocytic/ plasmacytic gastritis/enteritis/ colitis occurs in dogs and cats in response to what?
Hypersensitivity response to ingested dietary allergens
Lymphocytic/ plasmacytic gastritis/enteritis/ colitis is also a familial disease in some breeds such as the ___________.
Basenji
Lymphocytic/ plasmacytic gastritis/enteritis/ colitis is sometimes associated with specific agents such as _______________ and __________________.
Giardia
Trichomonas
Chronic eosinophilic gastritis/ enteritis/ colitis is associated with __________________.
Intestinal parasitic infections.
In intestinal lymphangiectasia, what will rupture of dilated lymphatics produce in the mesentery and serosal surface of the affected bowel?
Granulomas
True or false: Polyps of the canine rectum or colon are not uncommon.
True
Intestinal carcinomas are relatively uncommon except in ___________ (species) in certain areas of the world.
Sheep
Intestinal carcinomas are typically annular lesions which may cause ___________ of the bowel lumen.
Stenosis
Which of the following is FALSE about intestinal carcinomas?
a. Uncommon except in sheep in some areas of the world
b. Can affect any area of the small or large intestine
c. Typically annular lesion that can causes stenosis of the bowel lumen
d. Mucosal surface often ulcerated
e. Locally aggressive lesion, but rarely metastasizes
E – may metastasize widely
What cells are the endocrine tumors of the intestine derived from?
Enterochromaffin or Kulschitsky cells
Intestinal lymphoma is seen especially in which species?
Cats
Dogs
Horses
What does intestinal lymphoma look like?
Whatever it wants to look like
Nodules of tumor
Diffuse infiltrates
May look grossly and histologically like chronic enteritis and has similar clinical signs
Perianal gland tumors from the perianal hepatoid glands are typically (benign/ malignant).
Benign
Which perianal gland tumors are invariably malignant?
Apocrine glands of anal sac
Intestinal mast cell tumor, though rare, occurs in which species?
Dog and cat