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27 Cards in this Set

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Major depressive episode DSM-IV-TR
MI G SPACES
At least five of the following symptoms present for two weeks, one of which must be either M or I.
M - Mood depressed
I - Interest decreased
G - Guilt excessive or inappropriate
S - sleep (more or less)
P - psychomotor agition or retardation
A - appetite and or weight increase or decrease
C - concentration difficulty
E - energy more or less
S - suicidal
bereavement
constellation of depressive symptoms meeting criteria for a MDE appearing within 2 months of the death of a close friend or relative
Manic episode
DSM-IV-TR
GST PAID
a period of abnormally or persistently elevated, expansive, irritable mood lasting at least one week or less if hospitalised
during this period must have three of the following symptoms or four if the mood is only irritable
G - grandiosity
S - sleep, decreased need for
T - talkative, pressured speech
P - pleasure with painful consequences, e.g. spending all money, having sex with many peope
A - activity, goal-directed
I - ideas, flight of
D - distractability
symptoms do not meet criteria for mixed episode
mood distrubance is severe enough to cause psychotic features, marked impairment or necessitate hospitalisation
symptoms not substance induced or due to GMC
mixed episode
criteria met for both manic episode and MDE nearly every day for one week
hypomanic episode
criteria A of mania but duration is less than 4 days
criteria B and E of mania
change in functioning is present
not severe enough to cause MARKED impairment in functioning or hospitalisation
absence of psychotic features
MDD - epidemiology
prevalence: male 2 - 4%, female 5 - 9%
mean age of onset = 30 years
MDD - aetiology
genetic (higher concordance in monozygotic)
neutrotransmitter function at level of synapse (decreased activity of serotonin, noradrenaline, dopamine)
psychodynamic, e.g. persistent low self-esteem, poor attachment as child, abuse
cognitive, e.g. negative thinking
MDD with melancholic features
severely depresed
mood is worse in morning
early wakening
severe weight loss
excessive guilt
psychomotor retardation
MDD with atypical features
increased sleep
weight gain
leaden paralysis
chronic rejection sensitivity
depression in the elderly - what should you know?
accounts fo 50% of acute psych admission in elderly
high suicide risk
suicide peak in males 80 - 90, females 50 - 65
often presents with somatic complaints or anxeity symptoms rather than classic depression
differential diagnosis for MDE
adjustment disorder with depressed mood
bereavement
dementia
GMC
substance (steroids, alcohol, amphetamine crash)
anxiety disorder
dysthymia dsm-iv
A. depressed mood for most of the day, for more days than not, for at least two years
B. presence, while depressed of at least two of:
- poor appetite or overeating
- insomnia/hpersomnia
- fatigue
- low self-steem
- poor concentration or difficult to make decisions
- feelings of hopelessness
C. never without depressed mood for more than 2 months at a time
D. no evidence of past MDE, main, mixed, hypomainc episodes, cyclothymia
E. symptoms do not occur with a chronic psychotic disorder
F. not GMC or substance related
G. causing social or occupation dysfunction
baby blues - symptoms:
occurs in 50 - 80% of mothers, considered a normal emotional change
transient period of mild depression, mood instability, anxeity, decreased concentration, increased concern over own health and health of baby
baby blues - onest and duration
begins in 2-4 days postpatum
48 hours (usual) to 10 days
postpartum depression - diagnosis
sMDE
onset within four week postpartum
typically lasts 2 to 6 months but residual symptoms can last up to one year
post partum depression - always ask about?
suicidal and infanticial ideation
risk factors for PPD
previous history of a mood disorder
previous PDD
psychosical factors:
- stressful life events
- unemployment
- marital conflict
- lack of support from spouse, family, friends
PPD - SSRIs
short-term safety of maternal SSRIs for breastfeeding infants established, long-term unkonown
PPD - impact on child development
association with cognitive delay, especially in males and low SES groups
insecure attachment
increased behavioural disturbance at five years
post-partum psychosis - incidence
1-2 per 1000 childbirths, more common in primiparous women
postpartum psychosis - features
most often has an affective basis, usually manic, but can be depressive
mean onset 2-3 weeks postpartum
ranges 2 days to 8 weeks
may have suicidal or infanticidal ideation
previous history or family history of psychosis increases risk
postpartum psychosis treatments
SSRIs
mood stabilisers (not lithium because it is excreted into breast milk)
? ECT
bipolar disorder - epidemiology
prevalence: 0.6 - 0.9% of population
equal M:F
age of onset: teens to 20s
slight increase in upper SES
60 - 65% have family history of major mood disorders
cyclothymia
Cyclothymia is a persistent instability of mood characterised
by mild depression and mild elation, none of which are severe
enough to qualify for a formal diagnosis of bipolar affective disorder
or recurrent depressive disorder.
dysthymia
characterised by the presence of chronic low
mood, which must be present for at least 2 years but not severe
enough for a diagnosis of a depressive disorder. There may be
intervening periods of normal mood but these do not last longer
than a few weeks.
best treatment for atypical depression
monoamine oxidase inhibitors
premenstrual syndrome
Premenstrual syndrome is a collection of psychological (mood
disturbance, insomnia, poor concentration) and physical (headache,
bloating) symptoms occurring 24 hours after ovulation,
and quickly relieved by menstrual flow.