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47 Cards in this Set

  • Front
  • Back

What are the two components of anxiety?

What is this?

What is this?

Mood

What type of disorders?

What type of disorders?

Anxiety disorders

What are all these?

What are all these?

Major anxiety disorders

Recurrent panic attacks, occurring at over at least one month, involving anticipatory anxiety (the fear of having an attack) and avoidance of situations where panic is likely to occur or help is unavailable.



Which disorder?

Panic disorder

Palpitations, sweating, pounding heart, trembling, shaking, dyspnea, feeling smothered, etc. You've had one so you know the symptoms.

Panic attack (at least four must develop abruptly and reach a peak within 10 minutes)

Between what ages do panic attacks occur?


Can they be chronic and relapsing?


What is the prevalence and male to female ratio?

Early teens => 40s


Chronic, relapsing


1-3% community, 3-8% primary care


Female to male = 2:1

What is fear (or panic), often with blushing, of anticipated humiliation or rejection by others in social situations. While the person desires social activities and relationships, the dread of embarrassment leads to avoidance.

Social anxiety disorder (social phobia)

Which disorder is bimodal in onset (age 5 or early adolescence), chronic but may remit with positive social experiences?



It has a prevalence of 3-4% but performance anxiety is more common and a female to male ratio of 3:2 where more males seek treatment?

Social anxiety disorder (social phobia)

Familial modeling


Being bullied


Humiliation as a form of discipline


Disfiguring lesions (visible burns or deformities)



What are all of these?

Developmental experiences contributing to social phobia/avoidant personality disorder

What are phobias characterized by fear responses to specific cues?



When should they be treated?

Simple phobia


Treated only if they interfere with important activities

What condition should you be mindful of if patient needs MRI?



What is the response some have to situations that involve blood, needles, and injury?

Simple phobias:



Onset:



Animals?


Blood?


Situations?


May remit with experience



Prevalence? Which is more common in males?

Animals = 7


Blood = 9


Situations = 2-7 and early 20s



Prevalence = 11% (most common anxiety disorder)


Blood, injury, injection phobias more common in males

Diagnosis?

Diagnosis?

Agoraphobia

Identify what is being treated.

Identify what is being treated.

Persistant (>6 months) pattern of uncontrollable worries about health, safety, access to resources, and threats to other people. Multiple signs of arousal and autonomic dysfunction.



What is the disease? Onset? Female:male?

Generalized anxiety disorder


Onset = Mid teens to mid 20s (may occur after onset of chronic illness)


Duration > 6 months



Prevalance 5% (female:male 2:1)

Characterized by intrusive, arousal, and avoidance symptoms.


Onset males 6-15, females 20-29 (also post partum)


Gradual onset, 5% episodic, 15% severely deteriorate, waxes and wanes with stress


Prevalence 2%, males >females


Adults (males = females)

Obsessive-compulsive disorder

What are all of these?

What are all of these?

Common compulsions

What can all of these cause?

What can all of these cause?

Substance/Medication-Induced Anxiety disorder



Panic attacks predominate

What can all of these medical conditions cause?

What can all of these medical conditions cause?

Anxiety disorder

What type of disorder?

What type of disorder?

Mood disorder

What does SIG-E-CAPS stand for?



Sleep, loss of interest, guilt, energy, concentration difficulty, appetite disturbance, psychomotor retardation/agitation, suicidal thoughts



FIVE REQUIRED FOR A MAJOR DEPRESSIVE EPISODE

Is bereavement abnormal?


Can it turn into major depression? How is it treated?

What does this describe?

What does this describe?

Marked affective lability, irritability, anger, interpersonal conflicts, feeling on edge, anxiety, depression, over-eating, food cravings, sleep problems, feeling overwhelmed and out of control. All of this in the week before onset of menses.



Symptoms must last for most of year and be documents PROSPECTIVELY for at least 2 menstrual cycles. They must also disappear shortly after menses.



Diagnosis?

Diagnosis?

Diagnosis?

Cyclothymic disorder

Bipolar 1 or 2?

Bipolar 1 or 2?

Bipolar 1

Bipolar 1 or 2?

Bipolar 1 or 2?

Bipolar 2

Overeating, oversleeping while depressed, preserved reactivity to reward. Which mood features?

Atypical features

Detachment from the environment while awake; negativism including immobility, mutism, refusal to eat or drink. May be life threatening.

Catatonic features

Dense anhedonia, lack of response to reward, terminal insomnia (early morning awakening), diurnal variation (morning worse).



Melancholic features

Depressive episode within one month of childbirth by definition. Clinically this period of markedly increased risk may be >3 months. Often includes marked anxiety.

Postpartum onset

Marked congruent in depression: delusions of poverty, guilt, nihilism, illness, self-disgust; derogatory auditory hallucinations.



Mood congruent in mania: delusions of special powers or unlimited resources, paranoia, auditory hallucinations.

Psychotic features

Review table 47.1

Review table 47.1

Identify structure involved:



Short term memory



Cognitive inefficiency, recollection bias (depressed people cannot access happy memory; mania makes sad memory inaccessible)

Hippocampus

Identify structure involved:



Individual nuclei are part of three distinct circuits that link cortical areas with sensory cortices and subcortical structures. These regulate emotion, motivation, arousal, and attention.



Erratic arousal, subjective distress, compromised attention/concentration


Loss of pleasure responses to sensation in depression


Sometimes associated with hypersensitivity to sensory input in mania

Thalamus

Identify structure involved:



Conscious thought, executive functions (selection among alternatives, anticipation, inhibition of impulses, sequencing)



Helplessness, indecisiveness, hopelessness, distorted sense of time (slowed in depression, accelerated in mania)

Dorsolateral prefrontal cortex

Identify structure involved:



Assess risk in pursuit of reward, relate new information to context (memory and environment)



Overestimation of risk and reduced reward in depression; underestimation of risk in mania

Orbitofrontal cortex

Identify structure involved:



Integration of emotion and cognition



Abnormal motivation (apathy in depression)


Dysregulation or arousal

Anterior cingulate gyrus

Identify structure involved:



Fear, rage, selective attention



Anxiety, irritability, vigilance, hypersensitivity to negative environmental cues

Amygdala

Identify structure involved:



Reward



Lack of pleasure (depression), decreased or increased motivation

Nucleus accumbens

Identify structure involved:



Sleep, appetite, sexual behavior, metabolic rate, adaptation to acute or chronic environmental or social stress



Insomnia/hypersomnia, lack of or increased sexual interest, hyperphagia or anorexia

HPA axis