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19 Cards in this Set

  • Front
  • Back
tRNA
75 nucleotides long
Carries amino acids in activated form to the ribosome
Adopts a folded structure with internal base pairing
Eukaryote Ribosomes
80S, made up of 60S and 40S
60S = 49 proteins, 3rRNA
40S = 33 proteins, 1 rRNA
Prokaryote Ribosomes
70S, made up of 50S and 30S
50S = 34 proteins, 2 rRNA
30S = 21 proteins, 1 rRNA
Chymotrypsin
Cleaves peptides of Tyrosine, Typtophan, and phenalanine
Large and hydrophobic
Lined by hydrophobic residues
Trypsin
Cleaves proteins of Lysine and Arginine
Positivley charged side-chains bind
Elastase
Small and neutral
Alanine and Serine
Only small side chains can enter
Thrombin
Arganine to Glycine
Oxyanion hole
H bonds with NH on Gly93 and Ser193
Secure O-
Hemicellulose
Beta 1-4 polymers of D - xylopyranase
Sidegroups of carbohydrate polymers attached
500-3000 sugar units per polymer
Very good at cross linking as it is a branched polymer
Pectin
Family of mixture of branched polysaccarides
Rich in a1-4 linked D-galacturonic acid
Gelling agent in Jam
Agarose
Found in cell wall of red algae and seaweed
D-glactose linked beta-1-4 with galactose that has an ether bridge connecting C3 and C6
Some have a sulphate group
Very complex polysaccaride
Chitin
Main component of the exoskeleton
Polymer of N-acetyl glucosamine with beta-1-4 linkages
Glycosaminoglycans
Important as a matrix to hold together protein components of skin and connective tissue
Group includes; Chondoitin, Keratan, and Hyaluronan
Bacterial Cell Walls
Made up of peptidoglycan
Which is composed of alternating NAG and NAM linked by tetrapeptides of the amino acids Ala, Glu, Lys, ALa
Gram +ve, thick, multilayered, at surface
Gram -ve, thin, single layered, between membranes
Modifications during folding
Pepidyl prolyl isomerase catalyses proline isomerization
Protein disulphide isomerase (PDI) promotes correct disulphide bond formation
Pyramidines
Thymine and Cytosine
Smaller
Purines
Adenine and Guanine
Larger
How many hydrogen bonds does A to T have?
2
How many hydrogen bonds does G to C have?
3