Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
7 Cards in this Set
- Front
- Back
|
Molds - Inhalation danger. Any lab without bio safety cabinets can't work on molds EXCEPT dermatophytes.
|
4 Main criteria in mold identification: GCPB
1) Growth rate 2) Colonial and microscopic morphology 3) Presence of a yeast phase (is it dimorphic) 4) Biochemical test |
|
|
Mold Classification - 3 Groups (based on hyphae):
|
i) Hyaline: "Like glass", septate unpigmented hyphae, majority of medically important molds
ii) Dematiaceous: Septate pigmented hyphae, brown iii) Mucorales: Aseptate wide hyphae, lower fungi sometimes called pin molds |
|
|
Hyaline Molds (very common) - Aspergillus:
|
4 Common species, typically produce smoky gray/green colonies, imp. causes of fulminant fungal infections in immunocompromised patients (esp chemo patients)
- Aspergillus Fumigatus: Incriminated in farmer's lung - Aspergillus Niger : Otomycosis (fungal ear infection) - Aspergillus flavus : May infect immunocompromised patients, also infects peanuts producing aflatoxin associated with liver carcinoma - Aspergillus Terreus : Fourth species |
|
|
Hyaline Molds - Penicillium:
|
- Rapid growing green colony which you often see on moldy bread
-Source of penicillin - Penicillium marneffei |
|
|
Hyaline Molds - Dermatophytes: (Tinea / Ringworm)
|
- Large group of fungi infecting skin, hair, nails
- caused athlete's foot, resulting skin fissuring may predispose to bacterial cellulitis - Trichopyton, Microsporum, Epidermophyton - Large mat of fungal infection on head = a kerion - Jock itch commonly caused by Trichophyton mentagrophytes - Spores everywhere, skin infections. Athletes foot DOES NOT exist in populations without shoes Older men with lower limb cellulitis can be caused by athlete's foot |
|
|
Mucorales - soil, decaying veggies
|
- Cause mucormycosis (fungal infection of sinuses, brain, lungs), esp in immunocompromised
- Usually begins in nose, sinuses, very rapid fungal infection spread - Mucor, Rhizopus, Absidia, Cunninhamelia = most commonly associated with infection |
|
|
Indoor Molds, "Sick Building Syndrome"
|
- Only immunocompromised people at risk for invasive environmental mold infection
Atopic people (allergic) can have allergic reaction too - Unless immunocompromised or allergic, don't get illness from molds |
