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12 Cards in this Set
- Front
- Back
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Martha Chase and Alfred Hershey
(~1910~2000) |
worked with bacterial viruses
DNA is the genetic material |
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Rosalind Franklin and Maurice Wilkins
(1920-1958, 1916-2004) |
original double helical DNA structure proposition
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Walter Sutton
(1877-1916) |
Brachystola magna (grasshopper) experiment; large chromosomes to work with, allowing meiosis to be seen
chromosome theory of inheritance genes located on chromosomes in pairs |
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Thomas Hunt Morgan
(1866-1945) |
role of chromosomes in heredity
genes are on chromosomes Drosophila melanogaster (fruit fly) experiment formed basis of modern genetics |
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Gregor Mendel
(1822-1884) |
founder of genetics
pea plant experiment; hybrids; dominant/recessive laws of inheritance genotype influences phenotype |
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Frederick Griffith and Oswald Avery
(~1880~1940) |
DNA chemical structure of heredity
streptoccocus pneumoniae strains in DNA ; rough (non-virulent) vs smooth (virulent) in the mouse injection experiment (continued this exp with more detail and trails) the "transforming principle" of nonvirulent bacteria to virulent bacteria by DNA |
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Edward Tatum and George Beadle
(~1900~1980) |
neurospora crossa; bread mold experiment
auxotrophs - mutant spores that germinate on minimal medium "one gene--one enzyme" |
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Friedrich Miescher
(1868) |
first chemical studies of cell nuclei
pus bandages full of WBCs called them nuclein came up with chemical structure |
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Sir Archibald Garrod
(1902) |
alkaptonuria; black urine
recessive trait, inherited "DNA deficiency" connection between gene mutation and enzyme mutation |
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Erwin Chargoff
(1940) |
#A=#T and #C=#G
A+G=T+C base composition of DNA does not change per organism nor per organ of the same organism, however, the composition or amount will vary between species |
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Edmund Wilson and Nettie Stevens
(~1860~1920) |
identified accessory (X) chromosomes originally in insects
called them X and Y (or sex) chromosomes |
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James Watson and Francis Crick
(~1920~2000) |
structure of DNA
proposed the central dogma |
