Mod 8

Front 1

Name the vector and stage that affects humans in:
1. Toxoplasma
2. Trypanosoma cruzi
3. Trypanosoma gambiense and T. rhodesiense
4. Leishmani

Back 1

1. No vector- Tissue cyst in undercooked meat
2. Reduviid bug - trypomastigote in bug feces
3. Tsetse fly- trypomastigote in fly saliva
4. Sandfly- promastigote in fly saliva

Front 2

1. What is the definitive host for toxoplasmosis?
2. Present with?
3. How do you get it?
4. transmit mother to fetus?

Back 2

1. Intermediate hosts
2. cysts in tissues (cell-mediated immunity helps), sometimes resembles mono
3. cysts from uncooked meat or cat feces
4. yes, ka congenital infection of the fetus, happens when mother is infected during pregnancy

Front 3

1. Dx of taxoplasmosis?
2. prevent?
3. treat?

Back 3

1. Immunofluorescence assay for IgM antibody
2. cook meat, pregnant woman stay away from litter boxes
3. Combo of sulfadiazine and pyrimethamine

Front 4

1. What causes chagas disease?
2. What is it transmitted by?
3. Dx?
4. Where does it occur?
5. Rx?

Back 4

1. Trypanosoma cruzi
2. reduviid bug, through bite
3. Trypomastigotes in the blood stream (acute phase)
4. South america
5. nifurtimox

Front 5

Disease that presents with:
-inflammation at point of entry
-Facial edema and a nodule near the bite
-pseudocysts in almost every organ, esp heart
- anemia, weakness, chills, pain, fever, vomit, diarrhea
- heart failure and death

Back 5

Chagas disease (American Trypanosomiasis)

***Leads to enlarged heart and colon

Front 6

1. What causes sleeping sickness?
2. What is it transmitted by?
3. Where is it prevalent?

Back 6

1. Trypanosoma brucei (African trypanosomiasis)
2. Tsetse fly
3. africa

Front 7

What presents with:
fever, headache, muscle and joint ache, enlarged lymph nodes with 1-2 weeks, soon followed by symptomatic CNS invasion and death within months

Back 7

Sleeping sickness (african trypanosomiasis)

Front 8

1. Dx sleeping sickness?
2. Rx for Trypanosomiasis?

Back 8

1. trypomastigotes in blood
2. Nifurtimox

Front 9

1. What are the 2 types of leishmaniasis?
2. What is it spread by?
3. Dx?
4. Prevent?

Back 9

1. Cutaneous (most common, painless ulcers) and visceral (febrile illness, wt loss, hepatosplenomegaly)
2. Sand flies
3. Biopsy or scraping of the ulcer
4. Suppress the reservoir (dogs, rats, gerbils), suppress the vector, and prevent sandfly bites

Front 10

Stage that affects humans, stage in humans associated with disease, imp stage outside humans
1. Acanthamoeba
2. Naegleria Fowleri- get from swimming in the warm stagnant water, enters brain through cribriform plate

Back 10

1. Trophozoite, in eye, skin or meninges; cyst
2. Trophozoite, meninges; cyst