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70 Cards in this Set
- Front
- Back
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Digoxin
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Congestive Heart Failure
Most Used Poor Absoprtion/Metabolism |
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Digitoxin
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Congestive Heart Failure
Good Abospriton/Metabolism |
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Amrinone
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Congestive Heart Failure
IV/Hospital/Intense Cases |
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Congestive heart failiure
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The heart fails to pump enough blood out to the arteries or to keep up with venous return
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Angina
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The hearts own needs for oygenation are not being met (arteriolar sclerosis is the common culrpit)
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Fixed Angina
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Decrease Deman due to exercise or exertion
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Variant Angina
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Decreased Supply and spasm
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Unstable Angine
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When a fixed/variant angina suddenly changes its tune generally leading to an MI
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Organic Nitrates (nitrogylcerin)
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Dilate vessels to decrease preload to heart and stop plaque build up (angina)-Drug taken during sleep-contraindicated with erecticle dysfunction drugs
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Beta Blockers
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Kills the sympathetic system causing a more relaxed state (end in -olol) block intracellular calcium meaning less stress on heart and blocks vasconstrictive Renin II
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Renin 2
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Bodies most powerful circulating systemic vasoconstrictor
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Calcium Channel Blockers
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(Angina) Stop intracellular calcium that causes crossbridiging in muscles-
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Nifedipine (procardia)
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"For the heart" Angina-Calcium Channel Blocker-used for variant verision of angina-targets smooth muscle and peripheral resistace-reflex tachy
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Verapimil (calan)
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Angina-decreases Targets Cardiac Musclet-no reflex tachy-do not mix of digoxin for congestive heart failure
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Diltizem (cardizem)
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Angina-Stable/Variant-less side effects and effectivity-drug of choice-
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Stable Angina
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Increased Demand (treat Verapimil)
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Variant Angina
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Decreased Supply (treat with nifedpine)
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Cardiac Output
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Stroke Volume x Heart Rate
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Arterial Pressure
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Cardiac Output x Total Peripheral Restistance
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Respirin
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Adrenergic Neuronal Blockers (block norepi)-Can cause depression-
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Guanethidine
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Adrenergic Neuronal Blockers (block norepi transmission)-Does not cause depression-causes lethargy
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Methyldopa/Clonidine
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Central Sympathlytic-For mild hypertension-cause sexual dysfunction-sedation-edema
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Peripheral Sympthalytics (beta blockers)
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(block norepi secretion) good for post MI patients and asthmatic patients via B2 blockers
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Propanolol, timolol, nadolol
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Non selective beta blockers- (timolol key in glaucoma drops)
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meteprolol and atenolol
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selective beta 1 blockers (HTN)
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Pindolol and acebutolol
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partial agonists (HTN)
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Phenoxybenzamine-phentolamne
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Non selective alpha blockers (HTN)
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-Zosin drugs
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Selective alpha blockers-second line drug with diuretic for hypertension
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Diuretics
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First line drugs against HTN causes kidneys to secrete more urine by holding onto more sodium and fluids follow sodium
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HCTZ
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Diuretic (HTN)
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Furosemide (lasix)
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Diuretic (HTN)-Loop Type
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sprinolactone
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Diuretic (HTN)-Potassium Sparing
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"pril" Ace Inhibitors
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Blocks Angiotensin to Angiotensin 2-Angiotensin 2 is a vasoconstrictor
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Direct Renin Inhibitor (aliskiren)
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Decrease Renin = Decreased Angiotensin 2-can cause birth defects
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Angiotensin 2 Receptor Blockers
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"Sartan" can cause birth defects-MOA is obvious
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Hydralizine
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Direct Vasodilator (HTN)w/ preeclmapsia (HTN in pregnancy)
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Minoxidil
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Direct Vasodilator (HTN) can cause edema and reflex tachy
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LDL, HDL, Total Cholestrol, Trig #'s
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LDL <100
HDL >60 Total <200 Trig<150 |
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Questrin Colestid and Welchol
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Bile acid sequestrants which are the stupidest shit ever (LDL decreasors)
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HMG-COA Inhibitors "Statins"
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Decreased LD+Trig/ Increased HDL
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Nictonic acid (niaspan)
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Reduce VLDL production in liver therefore decreased LDL+Trig/Increased HDL
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Fibric Acid Derivitatves
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Fibr or Tri in there name tells you that they are fibric acid derived and treat triglcyerides only
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Cholestrol Absorption Inhibitors (ezetimibe)
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small intestine absoprtion of cholestrol is blocked to decrease LDL only (do not use with statins)
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Red RIce Yeast
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same as statin
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Omega 3 Fatty Acids
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Lovaza Rx- great for triglycerides and providing HDL
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Aspirin
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Anti Platelet-Irreversible-Gi problems
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Plavix (clopridgol)
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Anti Platelet-Irreversible-Gi Problems-Alternative to those allergic to Apirin
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Abciximad/epitifibatide/tirofiban
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Anti platelet for acute coronary problems AKA these are the most powerful anti platelets
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Warfaran
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Anti Coagulate-Inhibits Vitamin K coagulates, need to measure INR constantly
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Dabigatran (pradaxa)
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Anti Coagulate-Direct Thrombin Inhibitor- Complience is key for this drug-no INR problems
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Rivaroxaban
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Anti Coagulate-Targets XA factor
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Heparin
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Anti Coagulate-Targets thrombocin and XA factor and can be allergic to people since its pig derived
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thrombolytics
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destorys clots by activating natural plasminogen to plasmin reduction system-3 hour time window
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Anti Arrythmic Agents Type 1
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Sodium Channel Blockers
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Anti Arrythmic Agents Type 2
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Beta Blockers
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Anti Arrythmic Agents Type 3
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Block K+ Outflow (blocks calcium inflow in return)
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Anti Arrythmic Agents Type 4
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Ca2+ Channel Blockers that work directly on the heart
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Amiodarone-Type 3 AA
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Major AA Agent USED-56 day half life-extends action potential
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Drnedarone-Type 3 AA
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Similar to amiodarone with fewer side effects
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Verapimil-Type 4AA
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Stable Angina+Calcium Channel blocker in heart= AA-Causes constipation
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Rivaroxaban
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Anti Coagulate-Targets XA factor
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Heparin
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Anti Coagulate-Targets thrombocin and XA factor and can be allergic to people since its pig derived
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thrombolytics
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destorys clots by activating natural plasminogen to plasmin reduction system-3 hour time window
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Anti Arrythmic Agents Type 1
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Sodium Channel Blockers
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Anti Arrythmic Agents Type 2
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Beta Blockers
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Anti Arrythmic Agents Type 3
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Block K+ Outflow (blocks calcium inflow in return)
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Anti Arrythmic Agents Type 4
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Ca2+ Channel Blockers that work directly on the heart
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Amiodarone-Type 3 AA
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Major AA Agent USED-56 day half life-extends action potential
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Drnedarone-Type 3 AA
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Similar to amiodarone with fewer side effects
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Verapimil-Type 4AA
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Stable Angina+Calcium Channel blocker in heart= AA-Causes constipation
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