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10 Cards in this Set

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Penicillins
Bactericidal
B-lactam antibiotic
Inhibits bacterial cell way synthesis by binding to PBPs
Tetracyclines
Bacteristatic (can be cidal in high doses)
Reversible binding to ribosomal units to inhibit protein synthesis
Aminoglycosides
Bacteriocidal
Inhibits protein synthesis by binding to ribosomal units
Macrolides
Bacteristatic
Inhibits protein synthesis in bacterical cells by binding to 50s subunit
SMX/TMP:
SMX: interferes with bacterial folic acid synthesis and growth via
inhibition of DHF acid from para-aminobenzoic acid
Trimethoprim: inhibits dihydrofolic acid resulting in sequential
inhibition of enzymes of folic acid pathway
Clindamycin
Reversibly binds to 50s ribosomal subunits preventing
peptide bond formation thus inhibiting bacterial protein synthesis.
Bacteriostatic or bactericidal depending on drug concentration,
infection site and organism
Metronidazole
Disrupts DNA’s helical structure, inhibiting bacterial nucleic acid synthesis
Linezolid
Inhibits bacterial protein synthesis by interfering with the translations
Chlroamphenicol
Inhibition of proten synth. Binds to 50s Ribosomal unit inhibiting peptide bond formation
Vanco
Binds to precursor units of bacterial cell wall, inhibition their synthesis --> ↑ cell wall permeability (leaky). Also inhibits RNA synthsis