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22 Cards in this Set

  • Front
  • Back
pathogen for leprosy
Bacterium leprae
what is another name for leprosy
Hansen's Disease
how does pathogen avoid immune system
bacteria invade macrophages associated with peripheral nerves and respiratory tract
3 most common pathogens of bacterial meningitis
-Neisseria meningitidis
-Haemophilus influenzae (remember no correlation to influenza virus
-Streptococcus Iniae
meninges
membrane around brain and spinal cord; low immune system protection against pathogens
what are other types of meningitis-causing pathogens
-viral pathogens-->viral meningitis
-fungal pathogens-->fungal meningitis
pathogen for Lengionnaires
Legionella pneumophila
what habitat does the pathogen for Lengionnaires live in
water storage tanks, air conditioning systems, soil and aquatic habitats
how is Legionella pneumophila transmitted to humans
-water borne organism, inhaled droplets
-lives as a part of microbial community in water storage ranks, air conditioning systems, soil and aquatic habitats
-inhaled Legionella settles in the lungs
-air conditioning in buildings--> cooled water droplets fall into a water-based ecosystem-->formation of biofilms give rise to life (amoebas)--> amoebas are hosts for Legionella--> water droplets dry and become airborne--> inhaled by humans--> settles in the lungs (macrophages)
what is antigenic shift
segmented RNA genome shuffles two major antigens that are on the surface of the virus envelope
what is the most of transmission for antigenic shift
upper respiratory tract infection usually transmitted through inhalation of droplets of another infected person
how can influenza be transmitted from animals to humans
when animals and humans live in close proximity, reassortment of human-animal virus transmitted by intermediate host
why is there a concern about H5N1
-high rates of mutations
-has ability of acquire genes from other viruses
-a highly virulent form called "Highly Pathogenic H5N1" has high fatality
-highly virulent in some humans (but not transmitted human-to-human)
-infects lower respiratory tract of humans--> spreads slowly, often fatal
how was a potential outbreak of H5N1 in humans averted
Hong Kong- avian influenza strain H5N1- coincided with outbreak of influenza in poultry in Hong Kong. The entire poultry population was eliminated to stop spread of the disease
Measles
-rubeola virus
-infects respiratory tract
-symptoms: cough, fever, nasal discharge, eventually a rash developes
Mumps
-mumps virus; is spread by airborne droplets
-symptoms: inflammation of salivary glands, swelling of neck
-if virus spreads throughout body, occasionally leads to complications like sterility, encephalitis
Rubella
-German measles; rubella virus
-symptoms: milder than measles
-infection of fetus can result in stillbirth, heart, eye, and brain damage
what viruses cause the common cold
rhinovirus and coronavirus, also caused by adenovirus and others
how can rhinovirus evade immune system
virus contains many variations of surface proteins (serotypes)
what diseases are caused by varicella-zoster virus
Chickenpox and Shingles
Chickenpox
caused by varicella-zoster virus; highly contagious by airborne route-enters respiratory tract; develops characteristic lesions on face and upper trunk erupt, fill with pus, rupture, and covered by scabs; virus can remain in nuclei of nerves and sensory neurons
Shingles
when varicella-zoster virus becomes activated later in life-cause skin lesions