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4 Cards in this Set
- Front
- Back
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Necrotizing Fasciitis
Myconecrosis Gangrene |
Necrotizing Fasciitis- Destruction down to fascii +/- muscle
Myconecrosis- Gas Gangrene, destruction into muscle Gangrene-Loss of mass tissue |
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Clostridium Perfringens
(Pres? Timeline/source? VF/Toxins? Dx/Tx? |
(g+ anerobe with spores) ~6hrs after exposure acute cellulits with crepitus, borders of infection spread rapidly, visible changes within minutes; Exoenzymes=invasion, Alpha Toxin=Lecithinase. High risk =DM, Poor Circulation
Dx: Naglar Test (Yolk agar ½ w/alpha antitoxin, ½ w/o antitoxin; BAP- beta hemolysis with surrounding alpha hemolysis Tx: High Dose Penicillin, Hyperbaric Chamber, Amputation |
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Streptococcus Pyogenes
(VF****?/ presentation? Tx?) |
(g+ diplococcic in chains, GAS). Acute cellultis with Nitric Oxide filled vesicles, massive tissue/cell destruction and possible multiorgan failure; Streptolysin O = Hemolytic, M-Protein = Protects from phagocytosis;
Tx: Penicilin, Debriedment |
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Vibrio Vulnificus
(Pres/Timeline? Source/@risk? VF/Toxins? Seq/Dx? |
-(motile g- curved rod) Acute cellulitis 1-2d post warm saltwater/seafood exposure with Hemorrhagic Bullae. RTX Toxin = Cytolysin that punches holes in cell membranes, High risk= ImC or liver failure and eating raw oysters/saltwater- can become septic ~50 fatal.
Dx: PCR |
