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47 Cards in this Set
- Front
- Back
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Basic: D, TTT |
D+ Staging TTT: - Loc: CHI -->except: 1. function problem ( Anal/Neck 2. disseminated:SCLC - Loc-adv (=N1): adj CheTTT (=systemic disease) + RadTTT (except no isolation: CoCA)
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PrCA: FU n. RadTTT |
PSA, TR 6-12 Mo |
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MALT Lymphoma U H. Pylori: TTT |
PPI, Amoxi, Clarithro 14 d (= H. Pylori) |
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RectalCA: TTT (Stage) |
- Loc (N0): CHI - Loc-adj (N+): CHI + CheTTT (Folfox) |
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Lung nodules: Abk |
<4mm: - RF-->CT 12 Mo - No RF --> No FU > 4mm: CT, biopsy (>1 cm) |
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CervixCa: TTT |
CHI + RCT (Cisplantin) if high risk |
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KindneyCA: TTT |
CHI: <4cm partial, >4cm total (no need biopsy) CHI also if MT |
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PrCA: TTT |
- WW: life excpectancy <10y, Gleason <6 - Low risk (PSA <20, Gleason<8): Chi, RadTTT/BradyTTT. - High risk: RadTTT/ChiTTT + HormTTT (Gonerelin) - Mt/Recidive (PSA increase after TTT): HormTTT (Androgen depressive TTT=Gonerelin=GnRH +)
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SCLC: TTT |
RCT (Cisplantin) + Brain RadTTT |
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NSCLC: TTT |
- Loc (=N1, <7cm): Chi + Adj ChTTT (>3cm) - Advanced/MT: RCT +/- Cetuximab |
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BrCA: TTT loc |
Loc: 1- CHI: WLE/Mastectomy 2- RadTTT(if high risk local recurrence) 3- ChTTT: Cyclophos, Anthracycline (doxorubi), Taxane (docetaxol). Herceptin if HER+ 4- Hormon if ER+: 1. SERM (Tamoxifen) 2. Aromatose Inh.(Anastrazole, KI: pre-Mp) 3.Ovarectomy: pre-Mp. |
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BrCA: TTT advanced (+ def.) |
Advanced (= N2: fixed nodes/Mt): - Tamoxifen if ER+ - Evt. ChTTT - CNS Mt: Transtuzumab (Herceptin) if HER2+ - Biphosphonate 1x/mo |
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Bevacizumab (Avastin): I, PPH, UAW |
I: ColonCA: PPH: Receptor eGF blocker UAW: Poor wound healing, bleeding/thrombosis |
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Cancer unknown Primary: Def, Abk |
Def: CUP after CT Th-abd-pelvis + female Br/Gyn UTS, male Prostata/Test. UTS. zuUTS: if GI symptoms--> gastro/colo if cerv. LN--> Panendoscopy. |
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Mantle cell lymphoma: clin, D, TTT |
Clin: Extranodal manifestation (Bowel, BM) D: t (11;14) TTT: not curable |
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OesCA: TTT loc-reg |
Neoadj CRT, CHI |
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Lung adenoCA: Epi, Lab, TTT |
Epi: female asian non-smoker Lab: EGFR + TTT: Cetuximab (Erlatinib) |
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Renal CA: TTT if Mt |
CHI primary Tumor |
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Head-Neck CA: UTS, TTT loc/ Adv/ Mt |
UTS: panendoscopy: field of cancerization. Loc: CHI/RadTTT Adv: Multimodal (RCT, CHI) MT: CheTTT alone (rare distant Mt) |
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NET CA: TTT |
Depend Sy (DF, Flush, Wheezing, Local pain): - No Sy: wait and see (3Mo CT) - Sy: hepatic artery embolisation - Exception: Appendix--> CHI |
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CoCA: TTT, FU |
Loc: CHI Adv: CHI + adj. CheTTT (FOLFOX: folate, 5-FU, Oxalpaltin). Mt: CheTTT + CHI if 1 organ Mt (Lung/Mt) FU: UTS/CEA 6 Mo, Colo 1-3-5years, CT 1/y 5 y. |
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AnalCA: TTT |
RCT (no CHI) |
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Cutaneous T-Cell Lymphoma: clas, clin, TTT |
Clas: Mycosis fungoides/Sezary S Clin: erymatous plaques, CD4+ cells in blood. TTT: Alemtuzumab |
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Lambert-Eaton Syndrom: U, Clin |
U: SCLC Clin: proximal weakness, No deep tendon reflex, autonomic insufficiency. FACILITATION
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Melanoma: Excision margin |
< 1cm thick: 1cm margin excision > 1cm thick: sentinel LN, 2cm margin excision |
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Sup. Vena Cava syndrom: clin, Mng |
Clin: Facial/MS Edema, Facial Plethora, Dyspnea, Cough, Cynosis. TTT: after Diagnosis (LN/Mediastine biopsy) |
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CervicalCA: Clas--> TTT |
Ia micro: WW, conisation, Ib-II macro: hysterectomy/RadTTT, III-IV Pelvic wall-Bladder-Rectum: CHI + RCT (Cisplantin) |
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BrCA: TTT loc, loc adv, Mt |
- Loc: Lumpectomy/Mastectomy + RadTTT - Loc Adv: + Sentinel LN + RadTTT - Mt: Systemic TTT (CheTTT, Hormon), no CHI, Biphosphonate 1x/mo |
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UAW BrCA Che/EndrocrTTT: Trastuzumab (Herceptin), Tamoxifen, Anastrazole |
- Trastuzumab (Herceptin): cardiac tox - Tamoxifen: Thrombosis, UtCA, WW: SSRI - Anastrazole: Osteopenia |
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NHL aggressive: TTT DLBCL |
R-CHOP (+ HSCT if relapse) |
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Hairy cell Leukemia: Epi, Clin, TTT |
- Epi: Old male - Clin: pancytopenia, splenomegalie, no lymphadenopathy, dry BM biopsy - TTT: Clodribine 1 cycle |
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HL: Mng |
2-3 cycles ABDV-->PET scan: (+)--> complete CheTTT, (-)--> increase CheTTT |
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TestCA: Abk, TTT (markers) |
Abk: - alpha-FT-->Non Seminoma, - B-HCG-->Seminoma/Non-Seminoma TTT: CHI (Higher stage: RCT) |
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HSCT: I |
Young patient, bad prognostic factor, CLL/CML, DLBCL (after R-CHOP), MM, Follicular Ly relapse |
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Ov. CA: protective factor |
Multiparity, OAC |
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BrainMt: TTT |
CHI/Stereotactic RadTTT even if incurable |
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BladderCA: TTT, FU |
- Loc: TUR-B + BCG - Loc-Adv (Muscle): Chi/RCT - Mt: palliative RCT FU: cystoscopy + urine cytology |
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TLS: Epi, Lab, TTT |
Epi: Leukemia/BurkittLy (Turnover), DBLCL/CLL (bulky). Lab: uric acid, kalium, phosphate (AKI, crea), Hypocalciemia TTT: Hydratation, Allopurinol, Hemodyalisis |
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CLL: Prognosis marker |
Beta-2 Microglobuline, Gene modification, Cytogenetic (17p Del) --> = TTT-I + Sy and Age. |
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Recurrent BrCA: Mng |
Mng: ER/PR-->Tamoxifen HERr-2-->Herceptin |
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NET appendix: TTT (grade) |
Low grade: appendectomy High grade: hemicolectomy Mt liver: No sy--> WW |
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Spinal cord compression: TTT, Causes |
TTT: Emergency (GK, RadTTT/CHI) Causes: MM, PrCA, MaCA |
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Gastric CA: RF, TTT |
RF: H. Pylori TTT: CHI + RCT (5-FU) + Trastuzumab if HER2+ |
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Follic Ly: TTT (Indication) |
No Sy: WW Relapse: HSCT |
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Astrocytoma: TTT |
CHI +/- RadTTT |
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Pl. Effusion: max quantity |
max 1500ml drainage |
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malign hypercalcemia |
High Hydration + Biphosphonate |
