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7 Cards in this Set
- Front
- Back
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What is the prototype of the fluoroquinolones?
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Ciprofloxacin
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How does Ciprofloxacin work?
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Inhibits bacterial DNA gyrase (converts closed circular DNA into supercoiled configuration)
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What are the adverse effects of Ciprofloxacin?
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Tendon rupture
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Who cannot take Ciprofloxacin?
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Children under 18 year (tendon rupture)
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What are the drug interactions of ciprofloxacin?
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Catatonic compounds (avoid anything that contains Ca++, Al++, Zn++, Fe++, and Mg++)
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All the other fluoroquinolones end in:
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-floxacin
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What is Metronidazole used against?
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Protozoal Infections
Obligate Anaerobes |
