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7 Cards in this Set

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  • Back
What is the prototype of the fluoroquinolones?
Ciprofloxacin
How does Ciprofloxacin work?
Inhibits bacterial DNA gyrase (converts closed circular DNA into supercoiled configuration)
What are the adverse effects of Ciprofloxacin?
Tendon rupture
Who cannot take Ciprofloxacin?
Children under 18 year (tendon rupture)
What are the drug interactions of ciprofloxacin?
Catatonic compounds (avoid anything that contains Ca++, Al++, Zn++, Fe++, and Mg++)
All the other fluoroquinolones end in:
-floxacin
What is Metronidazole used against?
Protozoal Infections
Obligate Anaerobes