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103 Cards in this Set
- Front
- Back
Neuroscience |
The study of the nervous system and its role in behavior |
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Monism |
The mind and brain are the same thing |
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Dualism |
The mind and the brain are two separate things |
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Golgi Stain |
Randomly stains about 5% of neurons allowing them to jump out from other neurons |
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Myelin Stain |
Taken up by the fatty myelin on the axons to identify neural pathways |
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Nissl Stain |
Opposite of the myelin stain. identifies the cell bodies of neurons. |
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Tracer |
Trace pathways to determine origin or destination |
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Autoradiography |
make active neurons stand out. can be correlated with behavior |
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Immunochemistry |
Identifies receptors, neurotransmitters, or enzymes. Uses fluorescent dye and custom designed antibodies to target particular cellular components |
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In Situ Hybridization |
Constructs complementary strand of radioactive DNA to pair with active mRNA to make it light up |
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CT Scan |
Produces a series of 2D Xrays from different angles that computers combine to make a 3D image. Skull fractures. |
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MRI |
Measures the radio frequency waves emitted by the nucleus of hydrogen atoms when they are subjected to strong magnetic field |
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fMRI |
measures the brain activation by detecting the increase in oxygen levels in active neural structures |
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PET Scan |
injecting radioactive dye into the blood stream |
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Neurons |
10% of the brain. 100 billion in number. Communication cells |
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Glial cells |
Glue that holds the neurons together. make up the myelin sheath which protects axon and makes communication faster. more populous than neurons |
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Dendrites |
receive information at receptor sites from presynaptic cell |
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Cell Membrane |
Maintains cell/ controls cell environment. important in communication because electrical gradient signals travel around it. made up of lipid proteins |
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Cell body |
Produces DNA. Cell body stuff |
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Axon Hillock |
Location where neuron determines if it will fire or not. connects cell body/membrane to axon |
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Axon |
transports message length of neuron from one cell to the next |
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Myelin Sheath |
Protects axon and allows message to travel faster. Prevents cross communication |
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Nodes of Ranvier |
Allows message to maintain full strength by allowing an action potential to occur |
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Terminals |
release NT into synapse |
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Vesicles |
Hold NT in presynaptic cell |
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Receptor Sites |
Where NT binds on dendrites of cell |
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Motor neurons |
Multipolar. Muscles, organs and other neurons. responsible for movement |
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Sensory Neurons |
Unipolar or Bipolar. From senses to central nervous system |
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Interneurons |
Multipolar. between neurons in the same area. most numerous. |
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All-or-none Law |
Neuron fires completely or not at all. |
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Rate Law |
neurons fire faster in response to stronger stimuli |
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IPSP |
Inhibitory Post Synaptic Potential |
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EPSP |
Excitatory Post Synaptic Potential |
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Reuptake |
Neurotransmitters back into presynaptic cell into vesicles to be stored |
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Deactivation |
Enzymes tear apart specific NT's so they cannot bind on the postsynaptic cell |
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Autoreceptors |
Outside of synapse on the presynaptic cell and tell the cell to stop releasing NT's into the synapse |
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Glial Cells (Synaptic Modulation) |
Take neurotransmitters from synapse so they cannot bind to postsynaptic cell |
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Gyri |
bumps on the brain |
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Sulci |
indentations on the brain |
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Fissures |
big Sulci |
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Convoluted |
allows brain to store more information in a small area |
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Grey matter |
Cell bodies |
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White matter |
Cell axons |
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Meninges layers |
Top: Dura Mater Middle: arachnoid Inner: Pia mater |
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Frontal Lobe |
planning, organization, impulse control, emotion, behavior, primary motor cortex. humans only animal with large PFC--> inhibit inappropriate behaviors |
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Parietal Lobe |
body sensations, primary somatosensory cortex. processes skin senses and position and movement |
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Occipital Lobe |
Vision |
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Temporal Lobe |
Hearing. Advanced visual processing |
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Thalamus |
Central Relay. directs information |
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Hypothalamus |
Four F's : Fight, flight, feeding and fornicating. Life sustaining behaviors |
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Pituitary gland |
Hormones |
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Pineal Gland |
Melatonin. sleep/wake cycles |
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Corpus Callosum |
bridge between hemispheres that allows cross communication |
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Superior colliculi |
vision |
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Inferior colliculi |
hearing |
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substantia nigra |
involved in movement |
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ventral tegmental area |
reward. |
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medulla |
heart rate and respiration |
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pons |
sleep paralysis, arousal, REM dreams |
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Cerebellum |
balance, motor movement |
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ventricles |
contain cerebralspinal fluid. nutrient/waste control of the brain |
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amygdala |
emotions |
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hippocampus |
memory consolidation |
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drug |
a non-required substance that changes body function |
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psychoactive drug |
drug that has psychological effects |
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agonist |
mimics or enhances NT |
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antagonist |
blocks or decreases NT |
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addiction |
preoccupation with obtaining/using drug |
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withdrawal |
Negative reactions. opposite effects |
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tolerance |
decreased response with exposure to drug |
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dispositional tolerance |
an increase in drug metabolism. drug won't reach the same level or last as long |
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functional tolerance |
central nervous system becomes less sensitive to noticeable drug effects. "New Normal" |
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Behavioral (Learned) Tolerance |
learn ways to compensate for for effects. (ABC's backwards when drunk) |
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Cross tolerance |
extension of tolerance to similar drugs. work at same NT so they have to built up tolerance. (Addiction to Xanax = tolerance to alcohol) |
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Mixed tolerance |
tolerance to only some of the drugs effects (May not slur words but stumble when walking) |
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Reverse Tolerance |
Sensitization --> doesn't take as much to be sensitive again (THC binds to fat cells and stays in body so don't have to smoke as much to get high again) |
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Sensory Memory |
Milliseconds to seconds. High capacity. Not consciously aware. Loss through decay |
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Short-term memory |
seconds to minutes. limited capacity to 7 +- 2 items. consciously aware. loss through decay. |
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long-term memory |
days to years. high capacity. both consciously and unconsciously aware. lost through interference and decay |
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modal model of memory |
memory is gained in discrese stages with different characteristics sensory inputs -> sensory register+attention -> short-term memory + rehearsal -> long-term memory |
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Working memory model |
short term and long term memory work together in consolidation to manipulate information. Visuospatial sketch pad and phonological loop are coordinated by central executive to manipulate information |
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Declarative Memory |
can be explained in words |
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Episodic Memory |
Events |
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Semantic |
Facts |
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Nondeclarative Memory |
Hard to explain in words. more behaviors |
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Procedural Memory |
skills. motor and cognitive |
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Perceptual Representation System Memory |
Exposure to stimuli activates a network of information. Priming |
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Classical conditioning Memory |
Conditioned response between two stimuli |
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Nonassociative Memory |
Habituation: decreased response to a stimulus over time Sensitization: increased attention to a stimulus over time |
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Retrograde Amnesia |
Loss of long term memory. cannot remember past |
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Anterograde amnesia |
Loss of short term memory. cannot form new memories |
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CA1 Region of Hippocampus |
80% of memory success. consolidation |
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Learning |
a change in behavior, or the potential for that change, that indicates a permanent knowledge |
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neuroplasticity |
The ability of the brain to change and form new/stronger connections |
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LTP |
strengthening of long term memory: cells that fire together wire together |
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LTD |
weakening in strength of connections of neurons no longer activate each other. clears hippocampus for new stuff |
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ALTP |
Two stimuli occur at the same time. One elicits strong response. second elicits weaker response |
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ALTD |
Loss of second weaker stimulus eliciting response because of loss of the first stimulus so through association, the second is no longer paired with the first so no response is elicited |
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How Depression Treatments work |
increase receptor sensitivity and number. increase neural plasticity. trigger release of BDNF which is necessary for neurogenesis. increase cell death -> out with the old, in with the new. |
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factors related to surfacing of Schizophrenia |
divorce, seeing something traumatic, poor nutrition, various birthing factors, genetics |
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MAOI's |
non nicotine cigarette ingredients |
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Triclyclics |
block reuptake |
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Second generation antidepressants |
effect a single NT |