Miller Basic Science - Bone - Histology Of Bone

Front 1

Normal bone is called?

Back 1

Lamellar

Front 2

Immature and pathologic bone is called?

Back 2

Woven

Front 3

Lamellar bone can be these 2 types

Back 3

Cortical and Cancellous

Front 4

Describe Woven bone compared to Lamellar

Back 4

Immature and pathologic, more random with more osteocytes than lamellar bone, increased turnover, weaker, and more flexible than lamellar bone.

Lamellar bone is stress oriented; voven is not

Front 5

This type of bone makes up 80% of the skeleton

Back 5

Cortical

Front 6

Cortical bone is composed of tightly packed __1__ or __2__ connected by __3__ containing arterioles, venules, capillaries, nerves, and possibly lymphatic channels. __4__ lie b/w Osteons. __5__ frequently connect lamellae but do not cross __6__

Back 6

1. osteons
2. Haversion systems
3. Haversion or Volkmann's canals
4. Interstitial lamellae
5. Fibrils
6. Cement lines

Front 7

This is where bone resorption has stopped and new bone formation has begun; also define the outer border of an osteon

Back 7

Cement line

Front 8

This provides nutrition to cortical bone

Back 8

Intraosseous circulation (canals and canaliculi = cell processes of osteocytes)

Front 9

Compare Cortical bone to Cancellous bone
-turnover rate
-Young modulus
-resistance to torsion and bending

Back 9

-slower
-higher
-higher

Front 10

Osteoblasts form bone by generating this type of matrix

Back 10

organic, nonmineralized

Front 11

Osteoblasts are derived from these cells

Back 11

undifferentiated mesenchymal cells

Front 12

More differentiated, metabolically active osteoblasts line this part of bone

Back 12

bone surfaces

Front 13

Where do less active osteoblasts lie?

Back 13

"resting regions" or are entrapped cells and maintain the ionic milieu of bone

Front 14

What activates entrapped osteoblasts?

Back 14

Disruption of the active-lining cell layer of osteoblasts