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9 Cards in this Set

  • Front
  • Back

Presentation

5mg in 1mL

Pharmacology

Short acting CNS depressant

Actions

-anxiolytic


-sedative


-anti-convulsant

Metabolism

In the liver, excreted by the kidneys

Primary indications

-status epilepticus


-sedation to enable intubation


-post intubation sedation


-sedation to enable synchronised cardioversion


-sedation in the agitated Pt


-sedation in psychostimulant OD

Contraindications

Known hypersensitivity to benzodiazepines

Precautions

-reduced doses may be required for elderly/frail, Pts with chronic renal failure, CCF, or shock


-The CNS depressant effects of benzodiazepines are enhanced in the presence of narcotics and other tranquillisers including alcohol


-can cause severe respiratory depression in Pts with COPD


-Pts with myasthenia gravis

Side effects

-depressed level of consciousness


-respiratory depression


-loss of airway control


-hypotension

Onset


Peak


Duration

IM


3-5 mins


15 mins


30 mins


IV


1-3 mins


10 mins


20 mins