Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key


Play button


Play button




Click to flip

15 Cards in this Set

  • Front
  • Back
How are Chlamydia and Rickettsia similar?
They are 2 groups of Gram neg bacteria that are obligate intracellular parasites.
They need their hosts ATP as an energy source for their own cellular activity. They squander the cells ATP and refuse the ADP molecule(ATP/ADP translocator). Often Chlamydia do not possess this cytochrome system.
How do these organismdemonstrate growth?
On nonliving artificial media, it is almost impossible to culture them. They can be inoculated into chick embryos or cell culture.
Are these organisms similar to viruses?
Though they share ultramicroscopic size, and are obligate intracellular parasites, they have both RNA and DNA( while viruses have either DNA or RNA. Also, unlike viruses, they both synthesize their own proteins and are sensitive to antibiotics.
Chlamydia spreads by person-person contact, while Rickettsia spreads by arthropod vector. TRUE/FALSE
How is Chlamydia different from other Gram neg bacteria?
It has an inner and outer membrane. Unlike other Gram neg, it does not have a peptidoglycan layer and has no muramic acid.
Chlamydia is about the same size as some of the large viruses. TRUE/FALSE
What is Chlamydias tissue taxis/
It is fond of columnar epithelial cells that lines mucus membranes.(conjunctivitis, cervicitis and pneumonia)
What are the two forms of the Chlamydia life cycle?
1. Elementary body- it is metabolically inert(does not divide) small, about 300 nm infectious particle.
2. Initial body(reticulate body). Once inside a host cell, the elementary body inhibits phsgosome-lysosome fusion and grows to app 1000nm. Its RNA content increases. It synthesizes its own DNA, RNA and proteins, it requires ATP from the host.
What is the Chlamydial life cycle/
The elementary body is an infectious particle.
2. The EB attaches to and enters via endocytosis within epithelial tissue. The EB inhibits phagosome-lysosome fusion and is not destroyed. It transforms into an Initial body.
3. The host cell liberates the elementary body, which can infect more cells.
List three species of Chlamydia/
1. Chlamydia trachomatis(eyes, genitals, lungs)
2. Chlamydia psittaci(lungs)
3. Chlamydia pneumonia(lungs)
All are treated with tetracycline or erythromycin.
Chlamydia trachomtis is responsible for trachoma, a type of chronic conjunctivitis that is the leading cause of preventable blindness, TRUE/FALSE
What is Inclusion conjunctivitis?
Many babies delivered through birth canals infected with this organism, develop this condition.
There is a purulent yellow discharge and eyelid swelling, arising 5-14 days after birth. In the US, all newborns are given erythromycin eyedrops prophylactically.
How is this diagnosed?
By demonstarting basophilic intracytoplasmic inclusion bodies in cells taken from scrapings of the palpebral conjunctival surface.
When does Chlamydial pneumonia occur?
App. 4-11 weeks of life. This occurs as a result of passing through an infected birth canal. It is confirmed by the presence of anti-chlamydial IgM antibodies and demonstartion of C. trachomtis in clinical specimens.
What is the treatment of pneumonial C. trachomatis?