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10 Cards in this Set

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  • Back
Regarding enteric diarrhea, what are the three manifestations of intestinal invasion?
1. No cell invasionpbacteria bind to the intestinal epithelial cells but do not enter the cell. There is elecreolyte and fluid loss from intestinal epithelial cells.
2. Invasion of the intestinal epithelial cells
3. Invasion of lymph nodes and bloodstream.
Regarding invasion of intestinal epithelial cells, the cell penetration results in a systemic immune response with local white blood cell infiltration as well as fever. TRUE/FALSE
Describe lymph node invasion?
The deeper the invasion, systemic symptoms of fever, headache and WBC count elevation, and lymph node enlargement. Examples are Salmonella typhi, Yersinia enterocolitica, and Campylobacter jejuni.
Do enteric bacteria enter the pulmonary apparatus at any time?
Yes. When a patient aspirates vomitus that has been colonized by the enterics.
What is the general term fore the above incidence?
Hospital acquired gram- or nosocomial Gram -.
Is all E. coli in the colon harmless?
Generally yes, however there is an amazing amount of DNA being swapped about among the enterics by conjugation with plasmid exchange, lysogenic conversion by temperate bacteriophages, and direct transposon mediated DNA insertion.
Is the following statement true? "Nonpathogenic E. coli(normal flora) + virulence factors= disease".
List 4 virulence factors?
1. Mucosal interaction
2. Exotoxin production(Shiga like toxin)
3. Endotoxin: Lipid A portion of LPS.
4. Iron binding siderophore: obtains iron from human transferrin or lactoferrin.
List 4 diseases caused by E coli in the presence of virulence factors/
1. Diarrhea
2. Urinary tract infection
3. Neonatal meningitis
4. Gram neg sepsis in debilitated patients.
The severity of E. colidiarrhea depends on which factors the strain of E coli possesses> TRUE/FALSE