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6 Cards in this Set

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F. tularensis causes 2 forms of tularemia. Describe both forms.
Ulceroglandular form(70-80% handling of infected animals)
presents with ulcers at the site of infection, lymphadenopathy at the draining lymph nodes and fever.
The more severe form(typhoidal)(10-15% ingestion) often includes pneumonia and symptoms of bacteremia(fevers, chills, myalgias, malaise and weight loss.
How is F. tularensis spread?
Via vectors(ticks, deerflies mosquitoes, and handling of infected animals(rabbits and deer). In the US it is most commonly acquired from ticks.
How virulent is F. tularensis?
Highly virulent. Requires only 10-50 organisms to cause disease. Most laboratories will not culture it and there is concern over its bioterrorism potential.
F. tularensis has what special culture requirement?
Most strains require cysteine.
How is F. tularensis diagnosed?
Serological tests, since lab culture is dangerous.
What is the drug of choice for F. tularensis?
Streptomycin